Rosuvastatin inhibits norepinephrine-induced cardiac hypertrophy via suppression of Gh
Keywords: قلب و عروق; Rosuvastatin; Hypertrophy; G-proteins; Cardiomyocytes
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Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture
Keywords: قلب و عروق; ATP-sensitive K+ channel; Mitochondria; Rigor contracture; Reoxygenation; Cardiomyocytes
Opposing and synergistic effects of cyclic mechanical stretch and α- or β-adrenergic stimulation on the cardiac gap junction protein Cx43
Keywords: قلب و عروق; AKT; protein kinase B; API; activator protein 1; BIM I; bisindolylmaleimide I; CMS; cyclic mechanical stretch; Cx43; connexin43; CREB; CRE-binding protein; Ct; threshold cycle; EMSA; electrophoretic mobility shift assay; ERK1/2; extracellular signal-regul
Enhanced toxicity and ROS generation by doxorubicin in primary cultures of cardiomyocytes from neonatal metallothionein-I/II null mice
Keywords: قلب و عروق; Metallothionein; Doxorubicin; Cardiomyocytes; Reactive oxygen species
Proarrhythmic risk of embryonic stem cell–derived cardiomyocyte transplantation in infarcted myocardium
Keywords: قلب و عروق; Embryonic stem cells; Cardiomyocytes; Myocardial infarction; ProarrhythmiasCM, cardiomyocyte; ESC, embryonic stem cell; GFP, green fluorescent protein; H&E, hematoxylin and eosin; LV, left ventricular; LVEF, left ventricular injection fraction; MI, myocar
Zinc and cardiovascular disease
Keywords: قلب و عروق; Zinc; Metal ions; Micronutrients; Cardiomyocytes; Atherosclerosis; Diabetes
Urotensin II induction of adult cardiomyocytes hypertrophy involves the Akt/GSK-3β signaling pathway
Keywords: قلب و عروق; Urotensin II; Cardiomyocytes; Heart failure; Hypertrophy; Akt
Cytoskeleton mediates negative inotropism and lusitropism of chromogranin A-derived peptides (human vasostatin1-78 and rat CgA1-64) in the rat heart
Keywords: قلب و عروق; Vasostatin; Rat CgA1-64; Rat Langendorff heart; Inotropy; Lusitropy; Cardiomyocytes; Cytoskeleton;
The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells
Keywords: قلب و عروق; Human embryonic stem cells; Microwells; Embryoid body; Cardiomyocytes; Differentiation
An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes
Keywords: قلب و عروق; Panax quinquefolius; American ginseng; Nrf2; Oxidative stress; Cardiomyocytes; Cell death
The extracellular matrix: At the center of it all
Keywords: قلب و عروق; Extracellular matrix (ECM); Cardiac function; Cardiomyocytes; Cardiac fibroblasts; Endothelial cells; Cardiac development; Cell heterogeneity
TIMPs and cardiac remodeling: ‘Embracing the MMP-independent-side of the family’
Keywords: قلب و عروق; Tissue inhibitors of matrix metalloproteinase (TIMP); Matrix metalloproteinases (MMPs); Cardiac remodeling; Heart failure; Therapy; Receptor signaling; Endothelial cell; Angiogenesis; Fibroblast; Cardiomyocytes; Inflammation; Review
Imatinib does not induce cardiotoxicity at clinically relevant concentrations in preclinical studies
Keywords: قلب و عروق; ADP; adenosine diphosphate; ATP; adenosine triphosphate; AUC; area under the concentration-time curve; Cmax; maximal concentration; c-Abl; C-terminus of Abl gene; CML; chronic myeloid leukemia; ED; end-diastole; ER; endoplasmic reticulum; ES; end-systol
Effect of Fluid Shear Stress on Cardiomyogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells
Keywords: قلب و عروق; Mesenchymal stem cells; Differentiation; Cardiomyocytes; Shear stress; 5-Azacytidine
Exogenous expression of HIF-1α promotes cardiac differentiation of embryonic stem cells
Keywords: قلب و عروق; Embryonic stem cells; Hypoxia; Hypoxia inducible factor-1α; Cardiomyocytes; Sarcoplasmic reticulum function;
Yessotoxins: A toxicological overview
Keywords: قلب و عروق; Yessotoxin; Homo-yessotoxin; 45-Hydroxy-homoyessotoxin; Di-desulfo-yessotoxin; Marine algal toxins; In vivo toxicity; Cardiomyocytes; Ion channels; Cyclic AMP; Cyclic GMP; Lysosomes; E-cadherin; F-actin; Mitochondria; Apoptosis
5-HT4 and 5-HT2 receptors antagonistically influence gap junctional coupling between rat auricular myocytes
Keywords: قلب و عروق; Serotonin; 5-HT2A; 5-HT2B; 5-HT4a; 5-HT4b; Calcium current; cAMP; Connexin; Gap junction; Cx40; Cx45; Cx43; Cardiomyocytes; Syncytial properties
Succinate modulates Ca2+ transient and cardiomyocyte viability through PKA-dependent pathway
Keywords: قلب و عروق; Succinate; Cardiomyocytes; Calcium; PKA;
Activation of the cardiac Na+-Ca2+ exchanger by sorcin via the interaction of the respective Ca2+-binding domains
Keywords: قلب و عروق; Sorcin; Na+/Ca2+ exchanger; Ca2+-mediated interaction; Protein activation; Cardiomyocytes;
Preconditioning with Maillard reaction products improves antioxidant defence leading to increased stress tolerance in cardiac cells
Keywords: قلب و عروق; Advanced glycation endproducts; Cardiac fibroblasts; Cardiomyocytes; Oxidative stress; Preconditioning
Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis
Keywords: قلب و عروق; Metallothionein; Sepsis; Cardiomyocytes; Oxidative stress; ER stress; Autophagy
Proteins secreted by embryonic stem cells activate cardiomyocytes through ligand binding pathways
Keywords: قلب و عروق; Embryonic stem cells; Secreted proteins; Pluripotent stem cells; Cardiomyocytes; Intercellular signaling peptides and proteins; Paracrine signaling
Proteomic analysis in NSAIDs-treated primary cardiomyocytes
Keywords: قلب و عروق; NSAID; Cardiomyocytes; Proteomic analysis; Septin-8
BPAG1 isoform-b: Complex distribution pattern in striated and heart muscle and association with plectin and α-actinin
Keywords: قلب و عروق; DST; Cardiomyocytes; Cytoarchitecture
A cell-based sensor system for toxicity testing using multiwavelength fluorescence spectroscopy
Keywords: قلب و عروق; Autofluorescence; HL-1 cell line; Cardiomyocytes; Cytotoxicity screening; Drug testing; Microtiter plate; Tryptophan fluorescence; In vitro toxicity
Effects of late postconditioning on gene expression and cell death in neonatal rat cardiomyocyte cultures
Keywords: قلب و عروق; Cardiomyocytes; Anoxia–reoxygenation; Cell death; Postconditioning; mRNA expression
Electrophysiological Development of Transplanted Embryonic Stem Cell-derived Cardiomyocytes in the Hearts of Syngeneic Mice
Keywords: قلب و عروق; Embryonic stem cells; Cardiomyocytes; Transplantation; Electrophysiology; Development
Bio-technologies for a glandular stem cell cardiomyopexy
Keywords: قلب و عروق; Heart failure; Adult stem cells; Cardiomyocytes; Electrical stimulation; Capillaries; Cardiomyopexy; Cardiomyoplasty;
Cloning of large-conductance Ca2+-activated K+ channel α-subunits in mouse cardiomyocytes
Keywords: قلب و عروق; Large-conductance Ca2+-activated K+ (BKCa) channel α-subunit; Cardiomyocytes;
A microelectrode-based sensor for label-free in vitro detection of ischemic effects on cardiomyocytes
Keywords: قلب و عروق; Assay development; Impedance spectroscopy; Microelectrode array; Cardiomyocytes; HL-1 cell line; Ischemia model
Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing
Keywords: قلب و عروق; Arrhythmia; Fibrillation; Genetics; Nav1.5; SCN5A; Hyperexcitability; Electrophysiology; Atria; HL-1; Cardiomyocytes
Cyclosporin-A potently induces highly cardiogenic progenitors from embryonic stem cells
Keywords: قلب و عروق; Cyclosporin-A; Cardiac progenitor; Cardiomyocytes; Differentiation; Embryonic stem cells
Cardiac differentiation of P19CL6 cells by oxytocin
Keywords: قلب و عروق; Cardiomyocytes; Cell differentiation; Embryoid body formation; Oxytocin; P19CL6 cells
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells
Keywords: قلب و عروق; Human induced pluripotent stem cell; Human embryonic stem cell; Cardiomyocytes; Drug loading test; Arrhythmia
Molecular determinants of heart failure with normal left ventricular ejection fraction
Keywords: قلب و عروق; heart failure; diastolic function; cardiomyocytes; myofilamentary proteins; fibrosis; diabetes mellitus
Inhibition of farnesylpyrophosphate synthase prevents angiotensin II-induced hypertrophic responses in rat neonatal cardiomyocytes: Involvement of the RhoA/Rho kinase pathway
Keywords: قلب و عروق; Farnesylpyrophosphate synthase; Angiotensin II; Cardiomyocytes; RhoA; Geranylgeranylation
Sartan–AT1 receptor interactions: In vitro evidence for insurmountable antagonism and inverse agonism
Keywords: قلب و عروق; Sartans; AT1 receptors; Insurmountable antagonism; Inverse agonism; G proteins; Cardiomyocytes
Bone marrow derived stromal cells modified by adenovirus-mediated HIF-1α double mutant protect cardiac myocytes against CoCl2-induced apoptosis
Keywords: قلب و عروق; Bone marrow stem cells; HIF-1α; TGF-β1; Cardiomyocytes; CoCl2
Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway
Keywords: قلب و عروق; Cardiomyocytes; Ghrelin; Oxidative stress; Apoptosis; PI3K
The resistance of electron-transport chain Fe–S clusters to oxidative damage during the reaction of peroxynitrite with mitochondrial complex II and rat-heart pericardium
Keywords: قلب و عروق; Aconitase; Mitochondria; Cardiomyocytes; Complex II; EPR; Iron–sulfur clusters; Succinate dehydrogenase; Nitric oxide; Peroxynitrite
The protective effect of Ganoderma atrum polysaccharide against anoxia/reoxygenation injury in neonatal rat cardiomyocytes
Keywords: قلب و عروق; Ganoderma atrum polysaccharide; Antioxidant; Reactive oxygen species; Cardioprotection; Cardiomyocytes
Expression and tissue localization of β-catenin, α-actinin and chondroitin sulfate proteoglycan 6 is modulated during rat and human left ventricular hypertrophy
Keywords: قلب و عروق; Left ventricular hypertrophy; Cardiac remodeling; Cardiomyocytes; Vascular smooth muscle cells; Proteoglycans; Metalloproteinases; α-Actinin; β-Catenin; Angiotensin II
Cardiotin localization in mitochondria of cardiomyocytes in vivo and in vitro and its down-regulation during dedifferentiation
Keywords: قلب و عروق; Mitochondria; Cardiomyocytes; Remodeling; Dedifferentiation
Aldehyde dehydrogenase-2 (ALDH2) ameliorates chronic alcohol ingestion-induced myocardial insulin resistance and endoplasmic reticulum stress
Keywords: قلب و عروق; Alcohol; ALDH2; Cardiomyocytes; Insulin signaling
Alendronate affects calcium dynamics in cardiomyocytes in vitro
Keywords: قلب و عروق; Arrhythmia; Atrial fibrillation; Bisphosphonates; Calcium; Cardiomyocytes
The EGF receptor activates ERK but not JNK Ras-dependently in basal conditions but ERK and JNK activation pathways are predominantly Ras-independent during cardiomyocyte stretch
Keywords: قلب و عروق; Cardiomyocytes; Stretch; Mitogen activated protein kinases; Ras; EGF receptor
Adenine nucleotide translocase-1 induces cardiomyocyte death through upregulation of the pro-apoptotic protein Bax
Keywords: قلب و عروق; Cardiomyocytes; Mitochondrial permeability transition; Cell death; Bax; Reactive oxygen species
Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase β1-subunit
Keywords: قلب و عروق; Na,K-ATPase; Na,K-ATPase β1-subunit; Hypertrophy; Contractility; TAC; Ouabain; Cardiomyocytes; NCX1
Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction
Keywords: قلب و عروق; Oxidative stress; ER stress; Glutathione; Hearts; Cardiomyocytes; Metallothionein
Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts
Keywords: قلب و عروق; Induced pluripotent stem cells; Embryonic stem cells; Somatic cell reprogramming; Cardiomyocytes; Differentiation;