Keywords: Comparative genomics; Basidiomycete fungi; Ustilago maydis; Secretome; Cas9; Multiplexing;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: arrhythmia; genome editing; induced pluripotent stem cells; long QT syndrome; variant of uncertain significance; AP; action potential; APD; action potential duration; Cas9; CRISPR-associated protein 9; CRISPR; clustered regularly interspaced short palindr
Keywords: Breeding methods; Chrysanthemum morifolium; CRISPR/Cas9; Genome editing; Ornamental plants; Transgenic technologies; 4CL; 4-coumarate:coenzyme A ligase; C3H; coumarate 3-hydroxylase; C4H; cinnamate 4-hydroxylase; CCD4; carotenoid cleavage dioxygenase 4; C
Keywords: 5-HT; serotonin (5-hydroxytryptamine); A83-01; TGF-β kinase/activin receptor-like kinase inhibitor; ACTB; actin beta/beta-actin; ASCL1; achaete-scute homolog 1 (MASH1); ASOs; anti-sense oligonucleotides; Bcl-xL; b-cell lymphoma-extra large; BDNF; brain d
Keywords: Gene therapy; HIV; Gene editing; Targeted nuclease; Cas9; AAV;
Keywords: ADO; Autosomal dominant osteopetroses; ATP6V1B1; V-type proton ATPase subunit B, kidney isoform; CAII; carbonic anhydrase type II; Cas9; CRISPR associated protein 9; CLCN7; Chloride channel 7; CRISPR; clustered regularly interspaced short palindromic repe
Keywords: ARS; autonomously replicating sequence; CEN; centromere; CRISPR; Clustered, Regularly Interspaced, Short Palindromic Repeats; DSB; double strand break; GFP; green fluorescent protein; GRAS; Generally Regarded As Safe; gRNA; guide RNA (for CRISPR); HR; hom
Keywords: Cas9; virus; antiviral; HIV; HBV; HCV
Keywords: AAV4; adeno-associated virus serotype 4; BDNF; brain-derived neurotrophic factor; bFGF; fibroblast growth factor 2; BME; β-mercaptoethanol; BMP; bone morphogenetic protein; Cas9; CRISPR associated protein 9; Cla; claustrum; CN; caudate nucleus; CRISPR; c
Keywords: AAV; Adeno-associated virus; ARHL; age-related hearing loss; Cas9; CRISPR-associated nuclease 9; CRISPR; clustered, regularly interspaced, short palindromic repeat; crRNA; CRISPR RNA; dCas9; defective Cas9; DSBs; double-strand breaks; gRNA; guide RNA; HDR
Keywords: genome engineering; ZFNs; TALENs; CRISPR; Cas9; plant;
Keywords: Cancer models; Gene targeting; Transgenics; PDX; Cas9;
Keywords: CRISPR; Cas9; sgRNA; Guide RNA; Genome editing; Genome engineering
Keywords: functional genomics; noncoding; gene regulation; enhancer; CRISPR; Cas9
Keywords: Gene editing; Ethics; Cas9; Cpf1; Inherited retinal disease; Genetic ophthalmology
Keywords: Immunology; primary immunodeficiency; nuclear factor κB; autoimmunity; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; gene therapy; ADA; Adenosine deaminase; ADAM; A disintegrin and meta
The epithelial-mesenchymal transition induced by transcription factor LEF-1 is independent of β-catenin
Keywords: EMT; epithelial-mesenchymal transition; LEF-1; lymphoid-enhancer-binding factor 1; TCF; T-cell factor; KO; knockout; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated 9; PAM; protospacer-adjacent motif; DKO; do
Formation and nucleolytic processing of Cas9-induced DNA breaks in human cells quantified by droplet digital PCR
Keywords: DSB repair; DSB resection; Cas9; ddPCR; Gene editing;
Bombyx ortholog of the Drosophila eye color gene brown controls riboflavin transport in Malpighian tubules
Keywords: ABC transporter; Riboflavin; CRISPR/Cas9; Gene knockout; Malpighian tubules; Silkworm; ABC; ATP-binding cassette; ABCG; ABC transporter G family; AP-3; Adaptor Protein-3; BLOC; biogenesis of lysosome-related organelles complex; BLOS2; biogenesis of lysoso
Application and development of genome editing technologies to the Solanaceae plants
Keywords: Genome editing; Nuclease; Targeted mutagenesis; AGL; agamous-like; AID; activation-induced cytidine deaminase; ALOG; Arabidopsis LSH1 and Oryza G1; ANT; anthocyanin mutant; ARF; auxin-response factor; Aux; auxin-induced; BAK; brassinosteroid kinase; BOP;
Barhl1 is required for the differentiation of inner ear hair cell-like cells from mouse embryonic stem cells
Keywords: mESCs; mouse embryonic stem cells; iPSCs; induced pluripotent stem cells; CRISPR; clustered regularly interspaced short palindromic repeat; Cas9; CRISPR- associated protein 9; MEF; mouse embryonic fibroblast; EBs; embryoid bodies; EPL; early primitive ect
CRMP2-Neurofibromin Interface Drives NF1-related Pain
Keywords: ANOVA; analysis of variance; AP; action potential; Cas9; CRISPR-associated protein-9 nuclease; CaV2.2; N-type voltage-gated calcium channel; CGRP; calcitonin gene-related peptide; CNRP1; CRMP2-neurofibromin regulating peptide 1; CRISPR; clustered regula
CRISPR/Cas and recombinase-based human-to-pig orthotopic gene exchange for xenotransplantation
Keywords: CRISPR; Cas9; Xenotransplantation; Thrombomodulin; Gene replacement;
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
In vivo methods for acute modulation of gene expression in the central nervous system
Keywords: AAV; adeno-associated viruses; ADV; adenoviruses; ApoE; apolypoprotein E; BBB; blood brain barrier; cap; encapsulation; Cas9; CRISPR associated protein 9; cDNA; coding DNA; CMV; cytomegalovirus; CNS; central nervous system; CNT; carbon nanotubes; CRISPR;
A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding gene
Keywords: aa; amino acid(s); bp; base pairs; Cas9; CRISPR associated protein 9; cDNA; DNA complementary to RNA; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; DMSO; dimethylsulfoxide; Dox; doxycycline; dsDNA; double stranded DNA; FOXO; forkhead
FTO demethylase activity is essential for normal bone growth and bone mineralization in mice
Keywords: BMC; (bone mineral content); BMD; (bone mineral density); BMI; (Body mass index); Cas9; (CRISPR associated protein 9); CRISPR; (clustered regularly interspaced short palindromic repeats); CV; (calorific value); DEXA; (Dual-energy X-ray absorptiometry); EE
A Cas9 transgenic Plasmodium yoelii parasite for efficient gene editing
Keywords: Rodent malaria; Plasmodium yoelii; Genome modifications; Cas9; Knockin;
Efficient genome editing in Fusarium oxysporum based on CRISPR/Cas9 ribonucleoprotein complexes
Keywords: F. oxysporum; Cas9; Gene editing; Ribonucleoprotein; Bikaverin;
A detailed cell-free transcription-translation-based assay to decipher CRISPR protospacer-adjacent motifs
Keywords: Cas9; Cas12a; PAM; sgRNA; crRNA; TXTL;
Metabolic engineering of Saccharomyces cerevisiae by using the CRISPR-Cas9 system for enhanced fatty acid production
Keywords: Fatty acids; Cas9; Saccharomyces cerevisiae; CRISPR; Isocitrate dehydrogenase; ATP-citrate lyase;
Efficient transgene insertion in a pseudorabies virus vector by CRISPR/Cas9 and marker rescue-enforced recombination
Keywords: ASFV; African swine fever virus; BAC; bacterial artificial chromosome; Cas9; CRISPR associated protein 9; CRISPR; clustered regularly interspaced short palindromic repeats; DSB; double strand break; EGFP; enhanced green fluorescent protein; FBS; fetal bov
CRISPR-engineered genome editing for the next generation neurological disease modeling
Keywords: Neurological disorder; Brain tumor; Mouse model; CRISPR; Cas9;
Generation of SMURF2 knockout human cells using the CRISPR/Cas9 system
Keywords: SMURF2; CRISPR/Cas9; Knockout; Human cells; SMURF2; Smad Ubiquitination Regulatory Factor 2; HECT; homologous to E6-AP COOH-terminus; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated protein 9; ZFNs; zinc finger n
Genome-scale CRISPR pooled screens
Keywords: Genome engineering; Genetic screens; CRISPR; Cas9; Noncoding; Cancer; RNAi; RNA interference; CRISPR; clustered regularly interspaced short palindromic repeats; sgRNA; single-guide RNA; DSB; double-strand break; NHEJ; non-homologous end-joining; PCR; poly
Adaptation of CRISPR nucleases for eukaryotic applications
Keywords: CRISPR; Genome editing; Cas9; Cpf1; C2cx;
Methods for decoding Cas9 protospacer adjacent motif (PAM) sequences: A brief overview
Keywords: HEase; homing endonuclease; ZFN; zinc finger nuclease; TALEN; TAL-effector nuclease; DSB; double strand break; dCas9; catalytically inactive (dead) Cas9; RNP; ribonucleoprotein; Genome editing; CRISPR; Cas9; High-throughput methods; PAM library;
PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression
Keywords: Ribosomal RNA; Nucleolus; RNA polymerase I; rDNA; PAF53; A49; CRISPR/Cas9; Transcription; rDNA; ribosomal DNA; sgRNA; small guide RNA; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated protein-9 nuclease; Pol I; RN
Applications of CRISPR-Cas for synthetic biology and genetic recording
Keywords: CRISPR-Cas; Cas9; Synthetic biology; Genome editing; Genetic recording;
Original ArticleCRISPR-mediated targeting of HER2 inhibits cell proliferation through a dominant negative mutation
Keywords: Cas9; ERBB2; Breast cancer; PARP inhibitor; Trastuzumab; Therapeutic;
Mini-reviewApplication of CRISPR-mediated genome engineering in cancer research
Keywords: CRISPR; Cas9; Genome engineering; Cancer; Mouse models;
Advancing the design and delivery of CRISPR antimicrobials
Keywords: Bacteriophage; Cas9; CRISPR-Cas systems; sgRNA; Tail-fiber proteins;
Edited course of biomedical research: leaping forward with CRISPR
Keywords: CRISPR; Cas9; Cas13a; Gene modification; Gene modulation; CRISPR imaging; CRISPRi; CRISPRa; dCas9;
Analysing the outcome of CRISPR-aided genome editing in embryos: Screening, genotyping and quality control
Keywords: CRISPR; clustered regularly interspaced short palindromic repeat; Cas9; CRISPR associated 9; ddPCR; droplet digital polymerase chain reaction; DNA; deoxy-nucleotide acid; DSB; double stranded break; HDR; homology directed repair; indel; insertion/deletion
Research review paperDetection of on-target and off-target mutations generated by CRISPR/Cas9 and other sequence-specific nucleases
Keywords: CRISPR; Cas9; Genome editing; Engineered nucleases; Indel detection; Unbiased off-target analysis; Mismatch detection assays;
Review articleThe AAV-mediated and RNA-guided CRISPR/Cas9 system for gene therapy of DMD and BMD
Keywords: DMD; Duchenne muscular dystrophy; BMD; Becker muscular dystrophy; Dmd; the dystrophin gene; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated protein 9; gRNAs; guided RNAs; SpCas9; Cas9 from Staphylococcus pyogenes
Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA
Keywords: CRISPR; clustered regularly interspaced short palindromic repeats; CAS9; CRISPR associated protein; gRNA; guide RNA; PAM; protospacer adjacent motif; RNP; ribonucleoprotein; HDR; homology directed repair; hESCs; human embryonic stem cells; NHEJ; non-homol
Key elements for designing and performing a CRISPR/Cas9-based genetic screen
Keywords: CRISPR; Cas9; Genetic screen;
Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes
Keywords: Genome editing; CRISPR; Cas9; crRNA-tracrRNA; Ribonucleoprotein (RNP) complex; Homology directed repair (HDR);
Gene editing in mouse zygotes using the CRISPR/Cas9 system
Keywords: CRISPR; Cas9; Mouse; Zygotes; Gene editing;