Antitumor Activity of Polyuridylic Acid in Human Soft Tissue and Bone Sarcomas
Keywords: کاسپاز; soft tissue sarcomas; bone sarcomas; apoptosis; caspases; polyuridylic acid
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The role of caspase activation and mitochondrial depolarisation in cultured human apoptotic eosinophils
Keywords: کاسپاز; Eosinophils; Apoptosis; Mitochondria; Asthma; Caspases
Cell death mechanisms in the early stages of acute glutamate neurotoxicity
Keywords: کاسپاز; Caspases; Bcl-2 family; GSH; ROS; Peroxynitrite; Nitric oxide synthase
Effects of MPP+ on the molecular pathways involved in cell cycle control in B65 neuroblastoma cells
Keywords: کاسپاز; MPP+; Apoptosis; Caspases; Cell cycle; γH2AX
Tenderness – An enzymatic view
Keywords: کاسپاز; Post-mortem proteolysis; Meat tenderisation; Calpains; Calpastatin; Caspases
Time-course correlation of early toxic events in three models of striatal damage: Modulation by proteases inhibition
Keywords: کاسپاز; Quinolinate; 3-nitropropionic acid; Neurotoxicity; Calpains; Caspases; Protease inhibitors; Neuroprotection; Oxidative stress; Energy depletion; Cell damage
Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO
Keywords: کاسپاز; GIT-27NO, (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid–nitric oxide; VGX-1027, (S,R)-3-phenyl-4,5-dihydro-5-isoxasole acetic acidBreast cancer; TA3Ha; Apoptosis; Caspases; p53; Bcl-2; GIT-27NO; Nitric oxide; Free radicals
Involvement of caspase and MAPK activities in norcantharidin-induced colorectal cancer cell apoptosis
Keywords: کاسپاز; Norcantharidin; Colorectal cancer; Chemosensitivity; Caspases; Mitogen-activated protein kinase
Cytotoxic activity of naphthoquinones with special emphasis on juglone and its 5-O-methyl derivative
Keywords: کاسپاز; Naphthoquinones; Juglone; Cytotoxicity; Apoptosis; Caspases; Cell cycle;
Lysosomal rupture, necroapoptotic interactions and potential crosstalk between cysteine proteases in neurons shortly after focal ischemia
Keywords: کاسپاز; Apoptosis; Caspases; Cathepsins; Focal cerebral ischemia; Necrosis
Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis
Keywords: کاسپاز; DNA fragmentation; in vitro fertilization; oxygen radicals; oxidative stress; caspases; endonucleases; chemotherapy; ionizing radiation
Bid cleavage, cytochrome c release and caspase activation in canine coronavirus-induced apoptosis
Keywords: کاسپاز; Canine coronavirus type II; Apoptosis; Caspases; PARP; Bcl-2 family members
Aclarubicin-induced apoptosis and necrosis in cells derived from human solid tumours
Keywords: کاسپاز; Aclarubicin; Apoptosis; Necrosis; TUNEL; Caspases; PARP; Solid tumours
Serum biomarkers of cell death for monitoring therapy response of gastrointestinal carcinomas
Keywords: کاسپاز; Apoptosis; Biomarker; Cytokeratin; Caspases; Gastrointestinal cancer;
Differential regulation of caspase-9 by ionizing radiation- and UV-induced apoptotic pathways in thymic cells
Keywords: کاسپاز; Apaf-1; apoptosis protease-activating factor; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra long; Bid; BH3 interacting domain death agonist; BSA; bovine serum albumin; CBB; Coomassie brilliant blue; DAPI; 4â²,6-Diamidino-2-phenylindole; DISC; d
Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycin-resistant K562/A02 cells
Keywords: کاسپاز; compound of the substituted 1,3-dimethyl-1H-quinoxalin-2-ones QA3; multidrug resistance (MDR); P-glycoprotein (P-gp); ATP; ATPase; PKC; Apoptosis; caspases
Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy
Keywords: کاسپاز; Mitochondria; Iron; Sarcopenia; Muscle atrophy; Apoptosis; Caspases; Endonuclease G; Apoptosis-inducing factor
Role of individual caspases induced by astrovirus on the processing of its structural protein and its release from the cell through a non-lytic mechanism
Keywords: کاسپاز; Astrovirus; Virus release; Capsid protein processing; Caspases
Apoptosis induction in human leukemic cells by a novel protein Bengalin, isolated from Indian black scorpion venom: Through mitochondrial pathway and inhibition of heat shock proteins
Keywords: کاسپاز; Bengalin; Apoptosis; Mitochondria; Heat shock protein; Caspases
Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole-pyrrolobenzodiazepine conjugates
Keywords: کاسپاز; Pyrrolobenzodiazepine; 2,5-Diaryloxadiazoles; Anticancer activity; Apoptosis; p53; Caspases; Cyclin dependent kinase-2 (CDK-2);
Synthesis and induction of apoptosis signaling pathway of ent-kaurane derivatives
Keywords: کاسپاز; Kaurane derivatives; Cancer; Apoptosis; Caspases; Bcl-2; Death receptors; Mitochondria
Different contribution of BH3-only proteins and caspases to doxorubicin-induced apoptosis in p53-deficient leukemia cells
Keywords: کاسپاز; AIF, apoptosis-inducing factor; ΔΨm, mitochondrial transmembrane potential; DiOC6(3), 3,3′-dihexyloxa-carbocyanine iodide; PS, phosphatidylserineDoxorubicin; Caspases; Bcl-2 family proteins; BH3-only proteins; AIF
Mild thermotolerance induced at 40 °C increases antioxidants and protects HeLa cells against mitochondrial apoptosis induced by hydrogen peroxide: Role of p53
Keywords: کاسپاز; Oxidative stress; Hydrogen peroxide; Thermotolerance; Heat shock protein; Apoptosis; Caspases; Antioxidant; Mitochondria; p53 Protein
Glutathione redox status in mitochondria and cytoplasm differentially and sequentially activates apoptosis cascade in dopamine-melanin-treated SH-SY5Y cells
Keywords: کاسپاز; Melanin; GSH; Apoptosis; Caspases; Mitochondria; Parkinson's disease
Caspase cleavage of Itch in chronic lymphocytic leukemia cells
Keywords: کاسپاز; Hect; Ubiquitin; E3; Caspases; Apoptosis; p53; Chemotherapy; TRAIL; HDACi; CLL
Perfluorononanoic acid induces apoptosis involving the Fas death receptor signaling pathway in rat testis
Keywords: کاسپاز; Perfluorononanoic acid; Apoptosis; Testis; Caspases; Death receptor-dependent pathway
Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion
Keywords: کاسپاز; Sanguinarine; Apoptosis; Glutathione depletion; Caspases; A549 cells
MAPK activation is necessary to the apoptotic death of KB cells induced by the essential oil isolated from Artemisia iwayomogi
Keywords: کاسپاز; Artemisia iwayomogi; Essential oil; Apoptosis; Mitochondria; Caspases; Mitogen-activated protein kinase
N-Nitrosopiperidine and N-Nitrosodibutylamine induce apoptosis in HepG2 cells via the caspase dependent pathway
Keywords: کاسپاز; Apoptosis; Caspases; HepG2 cells; N-Nitrosamines; Reactive oxygen species;
Host cell death machinery as a target for bacterial pathogens
Keywords: کاسپاز; Programmed cell death (PCD); Apoptosis; Caspases; Bcl-2 like proteins; Survival pathways; Bacterial infection
ER-Golgi network-A future target for anti-cancer therapy
Keywords: کاسپاز; ER; ER stress; Golgi; Caspases; Apoptosis; Cancer; Therapy;
A single subcutaneous injection of ozone prevents allodynia and decreases the over-expression of pro-inflammatory caspases in the orbito-frontal cortex of neuropathic mice
Keywords: کاسپاز; Caspases; Orbito-frontal cortex; Allodynia; Ozone therapy; (Mouse)
Protection of insulin-producing cells against toxicity of dexamethasone by catalase overexpression
Keywords: کاسپاز; ROS, reactive oxygen species; RINm5F.Cat, catalase-overexpressing RINm5F cells; Dex, dexamethasone; ρ-NA, ρ-nitroaniline; CMV, cytomegalovirusOxidative stress; Glucocorticoids; Caspases; Necrosis; Insulin-secreting cells; Islets of Langerhans; Drug effect
PKCη confers protection against apoptosis by inhibiting the pro-apoptotic JNK activity in MCF-7 cells
Keywords: کاسپاز; PKC; protein kinase C; JNK; c-Jun N-terminal kinase; PARP-1; Poly ADP-ribose polymerase-1; MAPK; mitogen-activated protein kinase; CPT; Camptothecin; Tet; Tetracycline; PKCη; Apoptosis; UVC irradiation; Camptothecin; Cytochrome c; Caspases; JNK activity;
Mechanisms of clofibrate-induced apoptosis in Yoshida AH-130 hepatoma cells
Keywords: کاسپاز; Peroxisome proliferators; Clofibrate; Apoptosis; Caspases; ER stress
Activation of several concurrent proapoptic pathways by sulforaphane in human colon cancer cells SW620
Keywords: کاسپاز; Sulforaphane; Apoptosis; DNA-damage response; Caspases; Colon cancer, p53CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid; DCF, dichlorofluorescein; DFCH/DA, 2′-7′-dichlorodihydrofluorescein diacetate; DMEM, Dulbecco’s modified Eagle’s
Naphtho[2,3-d]isoxazole-4,9-dione-3-carboxylates: Potent, non-cytotoxic, antiapoptotic agents
Keywords: کاسپاز; Apoptosis; Bcl-XL; Caspases; Hepatocytes; Naphthoquinone derivatives
Effector caspase activation, in the absence of a conspicuous apoptosis induction, in mononuclear cells treated with azidothymidine
Keywords: کاسپاز; Azidothymidine; Caspases; Apoptosis;
Induction of apoptosis in human hepatocarcinoma SMMC-7721 cells in vitro by flavonoids from Astragalus complanatus
Keywords: کاسپاز; Flavonoids; Astragalus complanatus; Apoptosis; Caspases; Cell cycle; Microarray
Analysis of apoptosis induced by Caprine Herpesvirus 1 in vitro
Keywords: کاسپاز; CpHV-1; Apoptosis; Caspases; Cytochrome c; Bcl-2 family; PARP
γ-Tocotrienol induces mitochondria-mediated apoptosis in human gastric adenocarcinoma SGC-7901 cells
Keywords: کاسپاز; γ-Tocotrienol; Apoptosis; Caspases; PARP; SGC-7901 cells
Impact of physicochemical properties of engineered fullerenes on key biological responses
Keywords: کاسپاز; Nanoparticle; Cell signaling; Apoptosis; Free radical; Caspases; Carboxyfullerene;
Combination of N-(4-hydroxyphenyl) retinamide and genistein increased apoptosis in neuroblastoma SK-N-BE2 and SH-SY5Y xenografts
Keywords: کاسپاز; apoptosis; caspases; genistein; N-(4-hydroxyphenyl) retinamide; neuroblastomaATRA, all-trans retinoic acid; CTL, control group; DIF, double immunofluorescent; DIG, digoxigenin; DMSO, dimethyl sulfoxide; ER, endoplasmic reticulum; FITC, fluorescein isothio
Neuronal survival and resistance to HIV-1 Tat toxicity in the primary culture of rat fetal neurons
Keywords: کاسپاز; HIV-1 Tat; Neuronal cell culture; Toxicity; Caspases; MCP-1; NMDAR
Outer membrane proteins of wild-type and intimin-deficient enteropathogenic Escherichia coli induce Hep-2 cell death through intrinsic and extrinsic pathways of apoptosis
Keywords: کاسپاز; Enteropathogenic Escherichia coli; Apoptosis; TNFα; Caspases; c-jun N-terminal kinase
Targeting post-mitochondrial effectors of apoptosis for neuroprotection
Keywords: کاسپاز; ABD; ATP-binding domain; AIF; apoptosis-inducting factor; ANT; adenine nucleotide translocase; Antp HD; antennapedia homeodomain; Apaf-1; apoptotic peptidase activating factor 1; BH; Bcl-2 homology; BIR; baculoviral IAP repeat; boc-D-fmk; boc-Asp(OMe)-fmk
Increased Placental Apoptosis in Maternal Food Restricted Gestations: Role of the Fas Pathway
Keywords: کاسپاز; Apoptosis; Fas; FasL; Caspases; tBID; PARP
Caspase substrates and neurodegenerative diseases
Keywords: کاسپاز; Neurodegenerative diseases; Caspases; Substrates; Apoptosis; Survival; Huntingtin; APP; Tau; Preselinins; RasGAP; Rb; PARP
Chlamydia trachomatis can protect host cells against apoptosis in the absence of cellular Inhibitor of Apoptosis Proteins and Mcl-1
Keywords: کاسپاز; Chlamydia; Apoptosis; Caspases; Inhibitor of apoptosis proteins
Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity
Keywords: کاسپاز; Caspases; Substrate specificity; Caspase inhibitors; Fluoromethylketone (fmk) inhibitors; Aldehyde type of inhibitors