دانلود مقالات ISI درباره CDCA، اسید chenodeoxycholic + ترجمه فارسی

اسیدهای صفراوی و گیرنده 2 اسپینگوزین-1-فسفات در متابولیسم لیپید های کبدی

Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism

Keywords: CDCA، اسید chenodeoxycholic; Bile acid; Sphingosine-1 phosphate receptor; Heptic lipid metabolismABC, ATP-binding cassette; AKT/PKB, protein kinase B; BSEP/ABCB11, bile salt export protein; CA, cholic acid; CBA, conjugated bile acids; CDCA, chenodeoxycholic acid; CYP27A1, sterol 27-h

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

استرولبیوم روده انسانی: جنبه های اندوکرین اسید و صفراوی و صفات پزشکی

The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics

Keywords: CDCA، اسید chenodeoxycholic; APC, adenomatous polyposis coli; BA, bile acids; BSH, bile salt hydrolases; CA, cholic acid; CDCA, chenodeoxycholic acid; COX-2, cyclooxygenase-2; CRC, colorectal cancer; CYP27A1, sterol-27-hydroxylase; CYP7A1, cholesterol 7α-hydroxylase; CYP8B1, sterol 1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

پیشرفت های جاری در درمان دارویی برای یبوست مزمن

Current developments in pharmacological therapeutics for chronic constipation

Keywords: CDCA، اسید chenodeoxycholic; 5-HT, serotonin; CaCC, calcium-activated chloride channel; CC, chronic constipation; CDCA, chenodeoxycholic acid; CFTR, cystic fibrosis transmembrane conductance regulator; CIC, chronic idiopathic constipation; ClC-2, chloride channel protein 2; ENaC, epi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

عملکرد ماکروفاژهای شکل گرفته و ایمنی ذاتی توسط اسیدهای صفراوی: مکانیسم و ​​پیامدهای آن در بیماریهای کبدی کلستاتیک

Shaping macrophages function and innate immunity by bile acids: Mechanisms and implication in cholestatic liver diseases

Keywords: CDCA، اسید chenodeoxycholic; BEC, biliary epthelial cells; CA, cholic acid; CBP, CREB-binding protein; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; FXR, farnesoid X receptor; GR, glucocorticoid receptor; ISG, IFN-stimulated gene; PBC, primary biliary cirrhosis; PKI, PKA inhibi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

اثر آنتی بیوتیک های مختلف بر مدولاسیون میکروب بیوتین روده و پروتئین اسید صفرا در موش

Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice

Keywords: CDCA، اسید chenodeoxycholic; Abca1, ATP-binding cassette transporter a1; BA, bile acid; CA, cholic acid; Bsep, bile salt-export pump; CDCA, chenodeoxycholic acid; Cyp, cytochrome P450; DCA, deoxycholic acid; Fxr, farnesoid X receptor; GAPDH, glyceraldehyde 3-phosphate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

مصرف پنیر باعث کاهش غلظت کلسترول پلاسما بدون افزایش اسید معده می شود

Cheese intake lowers plasma cholesterol concentrations without increasing bile acid excretion

Keywords: CDCA، اسید chenodeoxycholic; Dairy; Bile acid; Cholesterol; Cardiovascular; Blood lipidsCA, cholic acid; CDCA, chenodeoxycholic acid; CVD, cardiovascular disease; DCA, deoxycholic acid; HDCA, hyodeoxycholic acid; HDL, high-density lipoprotein; LCA, lithocholic acid; LDL, low-density

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

اضافه کردن دگزامتازون باعث ایجاد ترکیب اسید صفراوی با القاء CYP8B1 در کشت های اولیه هپاتوسیت های انسانی می شود

Addition of Dexamethasone Alters the Bile Acid Composition by Inducing CYP8B1 in Primary Cultures of Human Hepatocytes

Keywords: CDCA، اسید chenodeoxycholic; BSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; CYP7A1, cholesterol 7α-hydroxylase; CYP8B1, sterol 12α-hydroxylase; CYP27A1, sterol 27α-hydroxylase; FXR, farnesoid X receptor; G6Pase, glucose-6-phosphatase; GR, glucocorticoid re

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Update on newborn dried bloodspot testing for cerebrotendinous xanthomatosis: An available high-throughput liquid-chromatography tandem mass spectrometry method

Keywords: CDCA، اسید chenodeoxycholic; CTX, cerebrotendinous xanthomatosis; ESI-MS/MS, liquid chromatography-electrospray ionization-tandem MS; DBS, dried bloodspots; 7α12αC4, 7α,12α-dihydroxy-4-cholesten-3-one; CDCA, chenodeoxycholic acid; GC–MS, gas chromatography–mass spectrometry; IRB, ins

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Determination of 7α-OH cholesterol by LC–MS/MS: Application in assessing the activity of CYP7A1 in cholestatic minipigs

Keywords: CDCA، اسید chenodeoxycholic; FXR, Farnesoid X receptor; CDCA, Chenodeoxycholic acid; OCA, Obeticholic acid; TPN, Total Parenteral Nutrition; DTT, dithiothreitol; PMSF, phenylmethanesulfonyl fluorideLC–MS/MS; CYP7A1; Cholesterol 7α-hydroxylase activity; 7α-OH cholesterol; Liver micros

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Novel FXR (farnesoid X receptor) modulators: Potential therapies for cholesterol gallstone disease

Keywords: CDCA، اسید chenodeoxycholic; FXR, farnesoid X receptor; CDCA, chenodeoxycholic acid; UDCA, ursodeoxycholic acid; 6EUDCA, 6-αethyl-ursodeoxycholic acid; qPCR, quantitative polymerase chain reaction; TGR5, G-protein-coupled receptor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity

Keywords: CDCA، اسید chenodeoxycholic; BSEP, bile salt export pump; CDCA, chenodeoxycholic acid; CRE, cAMP response element; CREB, cAMP-response element binding protein; DMT-MM, 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; 6-ECDCA/OCA, 6-ethylchenodeoxycholic acid/obetic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse

Keywords: CDCA، اسید chenodeoxycholic; Bile salt export pump; BSEP; ABCB11; Drug-induced liver injury; DILI; Bile salts; Hepatocytes; Species differenceBSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; DILI, drug-induced liver injury; GCA, glycocholic acid; GCDCA, glyc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Chenodeoxycholic acid reduces feed intake and modulates the expression of hypothalamic neuropeptides and hepatic lipogenic genes in broiler chickens

Keywords: CDCA، اسید chenodeoxycholic; ACC, acetyl-CoA carboxylase; ADPN, adiponectin; Adip-R1/2, adiponectin receptor 1 and 2; AgRP, agouti-related peptide; ATPcl, ATP citrate lyase; BW, body weight; CDCA, chenodeoxycholic acid; CRH, corticotropin releasing hormone; CXR, chicken xenobiotic-se

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration

Keywords: CDCA، اسید chenodeoxycholic; ABC, ATP-binding cassette; AMPK, AMP-activated protein kinase; BA, bile acid; CA, cholic acid; cAMP, cyclic adenosine monophosphate; CDCA, chenodeoxycholic acid; C/EBPβ, CCAAT-enhancer binding protein β; CTX, cerebrotendinous xanthomatosis; CYP7A1, choles

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice

Keywords: CDCA، اسید chenodeoxycholic; BAP, bile acid pool; Cyp7a1, cholesterol 7α-hydroxylase; CA, cholic acid; CDCA, chenodeoxycholic acid; MCA, muricholic acidBile acid pool composition; Cholesterol 7α-hydroxylase; Cholesterol absorption; Cholesterol synthesis; Hepatic cholesterol concentra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Drug-induced cholestasis detection in cryopreserved rat hepatocytes in sandwich culture

Keywords: CDCA، اسید chenodeoxycholic; AUC, area under the curve; BA(s), bile acid(s); Bsep/BSEP, bile salt export pump (rat/human); CDCA, chenodeoxycholic acid; CDF, 5-(6)-carboxy-2′,7′-dichlorofluorescein; CDFDA, 5-(6)-carboxy-2′,7′-dichlorofluorescein diacetate; CsA, cyclosporin A; DCA, deo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists

Keywords: CDCA، اسید chenodeoxycholic; ABCA1, ATP-binding cassette transporter A1; (ABC)G1, ATP-binding cassette sub-family G member 1; apoE, apolipoprotein; CDCA, chenodeoxycholic acid; DCCC, droplet-counter-current-chromatography; FXR, farnesoid-X-receptor; GAs, gymnemic acids; LXR, liver X

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro effects of active components of Polygonum Multiflorum Radix on enzymes involved in the lipid metabolism

Keywords: CDCA، اسید chenodeoxycholic; Acetyl-CoA, acetyl coenzyme A; Apo E, apolipoprotein E; CA, cholic acid; CDCA, chenodeoxycholic acid; CYP7A, cholesterol 7-alpha-hydroxylase or cytochrome P450 7A; DAG, diacylglycerol; DGAT 1, diacylgycerol acyltransferase 1; FA, fatty acid; FBS, fetal bo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and in vitro evaluation of bile acid prodrugs of floxuridine to target the liver

Keywords: CDCA، اسید chenodeoxycholic; 5-FU, 5-fluorouracil; Boc2O, di-tert-butyl dicarbonate; CDCA, chenodeoxycholic acid; DCC, N,N′-dicyclohexylcarbodiimide; DCM, dichloromethane; DMAP, 4-dimethylaminopyridine; DMEM, Dulbecco’s modified Eagle medium; DMF, dimethyl formamide; DMSO, dimethyl s

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

FXR activation improves myocardial fatty acid metabolism in a rodent model of obesity-driven cardiotoxicity

Keywords: CDCA، اسید chenodeoxycholic; Farnesoid X Receptor (FXR); Cardiomyopathy; Chenodeoxycholic acid (CDCA); Heart metabolismAOX, acyl-CoA oxidase; AKT, serine/threonine protein kinase PKB; BA, bile acid; CDCA, chenodeoxycholic acid; CD36, fatty acid Translocase; Coll α-1, collagen type I;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of N-Myc downstream regulated gene 2 by bile acids

Keywords: CDCA، اسید chenodeoxycholic; CDCA, chenodeoxycholic acid; EMSA, electrophoretic mobility shift assay; ENaC, epithelial sodium channel; FXR, farnesoid X receptor; HCC, hepatocellular carcinoma; I-BABP, ileal-bile acid-binding protein; IR1, inverted repeat separated by a nucleotide; MO

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Nuclear receptors, bile acids and cholesterol homeostasis series – Bile acids and pregnancy

Keywords: CDCA، اسید chenodeoxycholic; BSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; FXR, farnesoid X receptor; ICP, intrahepatic cholestasis of pregnancy; LCA, lithocholic acid; NTCP, Na+-taurocholate cotransporting polypeptide; UDCA, ursode

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease

Keywords: CDCA، اسید chenodeoxycholic; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; BA, bile acid; CA, cholic acid; DCA, deoxycholic acid; CDCA, chenodeoxycholic acid; TCA, taurocholic acid; TDCA, taurodeoxycholic acid; GCA, glycocholic acid; GDCA, glycodeoxycho

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism

Keywords: CDCA، اسید chenodeoxycholic; Abca1, ATP-binding cassette transporter a1; BA, bile acid; CA, cholic acid; Bsep, bile salt-export pump; CDCA, chenodeoxycholic acid; Cyp, cytochrome P450; DCA, deoxycholic acid; Fxr, farnesoid X receptor; Gapdh, glyceraldehyde 3-phosphate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

FXR signaling in the enterohepatic system

Keywords: CDCA، اسید chenodeoxycholic; Nuclear receptors; Farnesoid X receptor; Bile acids; Cholestasis; Liver disease; Enterohepatic circulationASBT, apical sodium dependent transporter; CA, cholic acid; CDCA, chenodeoxycholic acid; CREB, cAMP regulatory element-binding protein; DCA, deoxycho

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19

Keywords: CDCA، اسید chenodeoxycholic; CA, cholic acid; ChIP, chromatin immunoprecipitation; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; EMSA, electrophoretic mobility shift assay; FGF19, fibroblast growth factor 19; FXR, farnesoid X receptor; LCA, lithocholic acid; PCR, polymerase cha

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor

Keywords: CDCA، اسید chenodeoxycholic; ALT, alanine aminotransferase; BSEP, bile salt efflux pump; CAR, constitutive androstane receptor; CDCA, chenodeoxycholic acid; EC, (−)-epicatechin; ECG, (−)-epicatechin-3-gallate; EGC, (−)-epigallocatechin; EGCG, (−)-epigallocatechins-3-gallate; Fgf15, f

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Perspective: TGR5 (Gpbar-1) in liver physiology and disease

Keywords: CDCA، اسید chenodeoxycholic; CA, cholic acid; cAMP, cyclic AMP; CBDL, common bile duct ligation; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; eNOS, endothelial nitric oxide synthase; FXR, farnesoid X receptor; GLP-1, glucagon-like peptide-1; HSC, hepatic stellate cells; INT-77

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

A tandem mass spectrometric study of bile acids: Interpretation of fragmentation pathways and differentiation of steroid isomers

Keywords: CDCA، اسید chenodeoxycholic; APCI, atmospheric pressure chemical ionization; BA, bile acid; CA, cholic acid; CDCA, chenodeoxycholic acid; CID, collision-induced dissociation; DCA, deoxycholic acid; ESI, electrospray ionization; HDCA, hyodeoxycholic acid; IT, ion trap; LCA, lithocholi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Resistance to butyrate impairs bile acid-induced apoptosis in human colon adenocarcinoma cells via up-regulation of Bcl-2 and inactivation of Bax

Keywords: CDCA، اسید chenodeoxycholic; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; DCFH-DA, rhodamine-123, 2′,7′-dichlorofluorescein diacetate; DMSO, dimethyl sulfoxide; DPI, diphenyleneiodonium; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

FXR and PXR: Potential therapeutic targets in cholestasis

Keywords: CDCA، اسید chenodeoxycholic; BDL, bile duct ligation; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; FXR, Farnesoid X Receptor; LCA, lithocholic acid; LXR, liver X receptor; NR, nuclear receptor; PBC, primary biliary cirrhosis; PCN, pregnenolone 16α-carbonitrile

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Structural requirements of bile acid transporters: C-3 and C-7 modifications of steroidal hydroxyl groups

Keywords: CDCA، اسید chenodeoxycholic; ASBT, apical sodium dependent bile acid transporter; NTCP, sodium-taurocholate cotransporting polypeptide; HBSS, Hank’s balanced salt solution; SFB, sodium-free buffer; UDCA, ursodeoxycholic acid; CDCA, chenodeoxycholic acid; TCA, taurocholic acidASBT; NT

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular mechanism for the involvement of nuclear receptor FXR in HBV-associated hepatocellular carcinoma

Keywords: CDCA، اسید chenodeoxycholic; BSEP, bile salt export pump; CA, cholic acid; DBD, DNA-binding domain; DCA, deoxycholic acid; CDCA, chenodeoxycholic acid; CYP7A1, cholesterol 7α-hydroxylase; CYP8B1, cytochrome P450 sterol 12α-hydroxylase; FGF19/15, fibroblast growth factor 19/15; FXR, F

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications

Keywords: CDCA، اسید chenodeoxycholic; FXR, Farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptors; AF-1, activation function 1; AF-2, activation function 2; DBD, DNA binding domain; LBD, ligand binding domain; CDCA, chenodeoxycholic acid; FXRE, FXR response element;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling

Keywords: CDCA، اسید chenodeoxycholic; Egr-1, early growth response factor-1; DCA, deoxycholic acid; CDCA, chenodeoxycholic acid; MAPK, mitogen-activated protein kinases; FXR, farnesoid X receptor; Erk, extracellular signal-regulated kinase; BDL, bile duct ligationEarly growth response factor-

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

ESI-MS/MS quantification of 7α-hydroxy-4-cholesten-3-one facilitates rapid, convenient diagnostic testing for cerebrotendinous xanthomatosis

Keywords: CDCA، اسید chenodeoxycholic; CTX, cerebrotendinous xanthomatosis; CA, cholic acid; CDCA, chenodeoxycholic acid; ESI, electrospray ionization; MS/MS, tandem mass spectrometry; GirP, Girard P; CID, collision induced dissociation; LLOQ, lower limit of quantification; SPE, solid-phase ex

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

High performance liquid chromatography–tandem mass spectrometry for the determination of bile acid concentrations in human plasma

Keywords: CDCA، اسید chenodeoxycholic; CA, cholic acid; CDCA, chenodeoxycholic acid; CV, coefficient of variation; DCA, deoxycholic acid; GC–MS, gas chromatography-mass spectrometry; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; GDCA, glycodeoxycholic acid; GLCA, glycolithocholic a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Quantification of the 15 major human bile acids and their precursor 7α-hydroxy-4-cholesten-3-one in serum by liquid chromatography–tandem mass spectrometry

Keywords: CDCA، اسید chenodeoxycholic; C4, 7α-hydroxy-4-cholesten-3-one; CA, cholic acid; CDCA, chenodeoxycholic acid; CYP7A1, cholesterol 7α-hydroxylase; DCA, deoxycholic acid; ESI, electrospray ionisation; FDA, Food and Drug Administration; FXR, farnesoid X receptor; GCA, glycocholic acid; G

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Ku proteins function as corepressors to regulate farnesoid X receptor-mediated gene expression

Keywords: CDCA، اسید chenodeoxycholic; AF-1, activation function-1; AF-2, activation function-2; BSEP, bile salt export pump; CDCA, chenodeoxycholic acid; DBD, DNA-binding domain; DNA-PK, DNA-dependent protein kinase; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; FBS, fetal bovine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Rapid quantification of bile acids and their conjugates in serum by liquid chromatography–tandem mass spectrometry

Keywords: CDCA، اسید chenodeoxycholic; BA, bile acid; CA, cholic acid; CDCA, chenodeoxycholic acid; CV, coefficient of variation; DCA, deoxycholic acid; ESI-MS/MS, electrospray ionization tandem mass spectrometry; FDA, US food and drug administration; FXR, farnesoid X receptor; GC, gas chromat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Bile Salts Control the Antimicrobial Peptide Cathelicidin Through Nuclear Receptors in the Human Biliary Epithelium

Keywords: CDCA، اسید chenodeoxycholic; CDCA, chenodeoxycholic acid; ERK, extracellular regulated kinase; FXR, farnesoid X receptor; hBD-2, human β 2 defensins; PBC, primary biliary cirrhosis; PCR, polymerase chain reaction; VDR, vitamin D nuclear receptor; VDRE, VDR response element

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Chemical synthesis of N-acetylcysteine conjugates of bile acids and in vivo formation in cholestatic rats as shown by liquid chromatography/electrospray ionization-linear ion trap mass spectrometry

Keywords: CDCA، اسید chenodeoxycholic; BA, bile acid; CA, cholic acid; UDCA, ursodeoxycholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; LCA, lithocholic acid; NAC, N-acetylcysteine; GSH, glutathione; GST, glutathione S-transferase; CA-AMP, cholyl-adenylate; CA-CoA, cholyl-CoA th

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibition of the intestinal absorption of bile acids using cationic derivatives: Mechanism and repercussions

Keywords: CDCA، اسید chenodeoxycholic; ASBT; Enterohepatic circulation; Ileum; Intestine; Liver; Polyamine; TransportASBT, apical sodium-dependent bile acid transporter; BAPA, bile acid-polyamine derivative; BSEP, bile salt export pump; CDCA, chenodeoxycholic acid; GC, glycocholic acid; NTCP,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Nuclear bile acid receptor FXR as pharmacological target: Are we there yet?

Keywords: CDCA، اسید chenodeoxycholic; ABC, ATP binding cassette transporter; ASBT, apical sodium dependent bile acid transporter; BSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; CGD, cholesterol gallstone disease; CYP7A1, cholesterol 7α-hydroxylase; DCA, deoxycholic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy

Keywords: CDCA، اسید chenodeoxycholic; ABC proteins; Cholestasis; Estradiol; Pregnancy; TransportAHP, asymptomatic hypercholanemia of pregnancy; BAs, bile acids; BSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; CES1, human carboxylesterase-1; CsA, cyclosporin A; E217β

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Effects of chenodeoxycholic acid and deoxycholic acid on cholesterol absorption and metabolism in humans

Keywords: CDCA، اسید chenodeoxycholic; ANOVA, analysis of variance; apo, apolipoprotein; BID, twice a day; CA, cholic acid; CDCA, chenodeoxycholic acid; CAC, cholesterol absorption coefficient; CRC, Clinical Research Center; DCA, deoxycholic acid; DNA, deoxyribonucleic acid; FSR, free choleste

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Cytochrome P450s and cholesterol homeostasis

Keywords: CDCA، اسید chenodeoxycholic; acetyl-CoA, acetyl-coenzyme A; CA, cholic acid; CDCA, chenodeoxycholic acid; CTX, cerebrotendinous xanthomatosis; DHEA, dehydroepiandrosterone; HMG-CoA, 3-hydroxy-3-methylglutaryl coenzyme A reductase; P450 or CYP, cytochrome P450; PL, phospholipid; PUFA,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه