دانلود مقالات ISI درباره Cdk4 + ترجمه فارسی

Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase

Keywords: Rb; retinoblastoma; SV40; Simian vacuolating virus 40; hTERT; human telomerase reverse transcriptase; CDK4; cyclin-dependent kinase 4; BFFs; bovine fetal fibroblasts; PEFs; pig embryonic fibroblasts; CMV; cytomegalovirus; VSV-G; vesicular stomatitis virus

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

MiRNA in melanoma-derived exosomes

Keywords: Biomarker; Exosome; Melanoma; MicroRNA; MiRNA; AGO-2; argonaute protein 2; BMDCs; bone marrow-derived cells; BMP4; bone morphogenetic protein 4; CCND1; cyclin D1; CDK4; cyclin-dependent kinase; DGCR8; DiGeorge critical region gene 8; EMT; epithelial to me

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4

Keywords: GATA4; Cardiogenesis; CDK4;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Decorin deficiency promotes hepatic carcinogenesis

Keywords: SLRP; small leucine-rich proteoglycan; RTK; receptor tyrosine kinase; TA; thioacetamide; DEN; diethyl nitrosamine; HCC; hepatocellular carcinoma; Dcn−/−; decorin null; WT; wild type; p21WAF1/CIP1; cyclin-dependent kinase inhibitor p21; AP4; transcript

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

A new goniothalamin N-acylated aza-derivative strongly downregulates mediators of signaling transduction associated with pancreatic cancer aggressiveness

Keywords: Goniothalamin; N-acylated aza-derivatives; Pancreatic cancer; Panc-1 cells; AXL kinase; HIF-1α; GSH; glutathione; AXL; tyrosine-protein kinase receptor; ERK1/2; extracellular signal-regulated kinases 1 and 2; HIF-1α; hypoxia-inducible factor-1α; ROS;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

NFAT as cancer target: Mission possible?

Keywords: ADP; adenosine di-phosphate; AICD; activation-induced cell death; AKAP79; A-kinase anchor protein 79; Ang-2; angiopoietin-2; AP1; activator protein 1; ARRE-2; antigen receptor response element-2; BMP4; bone morphogenetic protein 4; CABIN1; calcineurin-bin

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

A possible usage of a CDK4 inhibitor for breast cancer stem cell-targeted therapy

Keywords: Breast cancer; Cancer stem cells; CDK4; Radiotherapy; Differentiation therapy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Hypoxia downregulates PPARγ via an ERK1/2-NF-κB-Nox4-dependent mechanism in human pulmonary artery smooth muscle cells

Keywords: PPARγ; peroxisome proliferator-activated receptor-γ; PH; pulmonary hypertension; HPASMC; human pulmonary artery smooth muscle cell; NF-κB; nuclear factor-κB; Nox4; NADPH oxidase 4; ERK1/2; extracellular signal-regulated kinase 1/2; aP2; adipocyte prot

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (−/−) mice

Keywords: MAC; membrane attack complex; ApoE (−/−) mice; ApoE knockout mice; CDK4; cyclin dependent protein kinase 4; AS; atherosclerosis; HE; hematoxylin/eosin; GPI; glycosylphosphatidyl inositol; TC; total cholesterol; TG; triglyceride; LDL; low density lipop

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Atypical lipomatous tumor mimicking giant fibrovascular polyp of the esophagus: report of a case and a critical review of literature

Keywords: Atypical lipomatous tumor; Liposarcoma; Esophagus; Fibrovascular polyp; MDM2; CDK4

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Dedifferentiated liposarcoma of the spermatic cord with a hemangioendothelioma-like component: A case report and review of the literature

Keywords: Dedifferentiated liposarcoma; D2-40; MDM2; CDK4; Hemangioendothelioma

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Nuclear factor of activated T-cells 1 increases sensitivity of v-myb transformed monoblasts to all-trans retinoic acid

Keywords: BM2wt; BM2 wild type cells; BM2NFAT1; BM2 cells transfected with the pEGFP.N1-NFAT1 plasmid; BM2VIVIT; BM2 cells transfected with the pEGFP.N1-VIVIT plasmid; BM2mock; BM2 cells transfected with the pEGFP.N1 plasmid; ATRA; all-trans retinoic acid; CDK4; cy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The ClC-3 chloride channel protein is a downstream target of cyclin D1 in nasopharyngeal carcinoma cells

Keywords: Cyclin D1; ClC-3; CDK4; CDK6; Chloride channels;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

C-peptide induces human renal mesangial cell proliferation in vitro, activating Src-kinase, PI-3 kinase and ERK1/2

Keywords: CDK4; cyclin-dependent kinase 4; DAPI; 4′,6-diamidino-2-phenylindole; ERK1/2; extracellular-signal-regulated kinases; LY294002; PI-3 kinase inhibitor; MC; mesangial cells; PD98059; MAP/ERK kinase inhibitor; PDGF; platelet derived growth factor; PP2; pro

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of Plk1 and Pin1 by 5′-nitro-indirubinoxime suppresses human lung cancer cells

Keywords: Lung cancer; 5′-Nitro-indirubinoxime (5′-NIO); Plk1; Pin1; Cdk4; Rb

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Suppression of PRMT6-mediated arginine methylation of p16 protein potentiates its ability to arrest A549 cell proliferation

Keywords: TUNEL; terminal deoxynucleotidyl transferase-mediated (dUTP) nick end-labeling; PRMT; protein arginine methyltransferase; FACS; flow cytometric analysis; CoIP; co-immunoprecipitation; FBS; fetal bovine serum; RNAi; RNA interference; siRNA; small interferi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Development of a time-resolved fluorescence resonance energy transfer assay for cyclin-dependent kinase 4 and identification of its ATP-noncompetitive inhibitors

Keywords: ATP noncompetitive; CDK4; High-throughput screening; Inhibitor; Kinase; TR-FRET;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Fullerene derivative prevents cellular transformation induced by JAK2 V617F mutant through inhibiting c-Jun N-terminal kinase pathway

Keywords: Cdk4; cyclin-dependent kinase 4; DCFH; dichlorodihydrofluorescein; DMSO; dimethyl sulfoxide; Epo; erythropoetin; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; i.p.; intraperitoneal; i.v.; intravenous; Jak; Janus kinase; JNK; c-Jun N

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Transcriptional control of cell cycle-dependent kinase 4 by Smad proteins-implications for Alzheimer's disease

Keywords: Alzheimer's disease; Smad4; Cell cycle; Cdk4; Promoter; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is inversely correlated with p16 expression

Keywords: MRT, malignant rhabdoid tumor; INI1, integrase interactor 1; CDK4, cyclin-dependent kinase 4; PD, PD 0332991; siRNA, small interfering RNA; PCNA, proliferating cell nuclear antigen; GAPDH, glucose-6-phosphate dehydrogenasePD 0332991; CDK4; p16; Rhabdoid t

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Vitamin D3 up-regulated protein 1 deficiency accelerates liver regeneration after partial hepatectomy in mice

Keywords: Akt; ERK1/2; Growth factor; Liver regeneration; VDUP1; BrdU; 5-bromo-2´-deoxy-uridine; CDK2; cyclin-dependent kinase 2; CDK4; cyclin-dependent kinase 4; EGF; epidermal growth factor; ERK1/2; extracellular signal-regulated kinase 1/2; GSK3β; glycogen syn

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers

Keywords: Pyrrolo[2,1-c][1,4]benzodiazepines; 1,2,3-Triazoles; Chalcones; Anticancer activity; Apoptosis; Cyclin D1; Cdk4; NF-kB

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of the Unfolded Protein Response Is the Core of MicroRNA-122-Involved Sensitivity to Chemotherapy in Hepatocellular Carcinoma

Keywords: miRNA; microRNA; ER; endoplasmic reticulum; PSMD10; proteasome 26S subunit, non-ATPase, 10; CDK4; cyclin-dependent kinase 4; UPR; unfolded protein response; GRP78; glucose-regulated protein 78; HCC; hepatocellular carcinoma; DOX; doxorubicin;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Cell cycle regulated expression of NCoR might control cyclic expression of androgen responsive genes in an immortalized prostate cell line

Keywords: AR; androgen receptor; ARBS3.12AR; binding site on chromosome 3; ARE; androgen response element; CBP; calmoduline binding peptide; CDK4; cyclin dependent kinase 4; ChIP; chromatin immunoprecipitation; CYR61; cysteine-rich, angiogenic inducer, 61; DNA; deo

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

IKKβ specifically binds to P16 and phosphorylates Ser8 of P16

Keywords: P16; Phosphorylation; IKKβ; CDK4

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Mammalian target of rapamycin complex 1 signaling opposes the effects of anchorage loss, leading to activation of Cdk4 and Cdc6 stabilization

Keywords: mTORC1; mammalian target of rapamycin complex 1; ECM; extracellular matrix; S6K1; S6 kinase 1; Rb; retinoblastoma protein; REF; rat embryonic fibroblast; Eker REF; Eker (Tsc2−/−) rat embryonic fibroblast; 4EBP; eIF4E binding protein; ALLN; N-acetyl-le

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Why pyridine containing pyrido[2,3-d]pyrimidin-7-ones selectively inhibit CDK4 than CDK2: Insights from molecular dynamics simulation

Keywords: CDK2; CDK4; Ligand binding; Molecular dynamics; Selectivity

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro

Keywords: Stem/Progenitor Cells; Epithelial Mesenchymal Transition; Self-Renewal; Multilineage Differentiation; BIO; bromoindirubin-3-oxime; 2D; two-dimensional; 3D; three-dimensional; Cdk4; cyclin-dependent kinase-4; EGF; epithelial growth factor; GSK-3β; glycoge

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Immortalization of murine muscle cells from lysosomal α-glucosidase deficient mice: A new tool to study pathophysiology and assess therapeutic strategies for Pompe disease

Keywords: Pompe disease; Glycogen storage disease type II; Myoblast immortalization; α-Glucosidase; CDK4

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Diethylnitrosamine (DEN) induces irreversible hepatocellular carcinogenesis through overexpression of G1/S-phase regulatory proteins in rat

Keywords: Diethylnitrosamine (DEN); Irreversible hepatocelluar carcinogenesis; G1/S phase regulatory protein; cdk4;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Tight junctions and the regulation of gene expression

Keywords: ZO-1; ZO-2; ZO-3; ZONAB; DbpA; Cell cycle; Cyclin D1; PCNA; erbB-2; CDK4; Apg-2; Symplekin RalA; Occludin Claudin; JAM; Cingulin GEF-H1; Beta-catenin; E-cadherin; VE-cadherin; Ras; TGF-beta; Snail; Slug; Glucocorticoid; Gene methylation; Epithelial–mesenc

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Identificación de alteraciones genéticas en oligodendrogliomas mediante amplificación dependiente de ligasa de múltiples sondas (MLPA) (multiple ligationdependent probe amplification)

Keywords: Oligodendrogliomas; Deleción lp/19q; MLPA; EGFR; CDKN2A; PTEN; Oligodendrogliomas; 1p/l9q deletion; MLPA; EGFR; CDKN2A; PTEN; ADN; ácido desoxirribonucleico; GAC1; repeticiones ricas en leucina del componente neuronal 2; CAMTA1; activador de la trascrip

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex

Keywords: LIN-9; Mip/LIN-9; Cell cycle; CDK4

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Molecular mechanism of cell proliferation in rodent uterus during the estrous cycle

Keywords: Uterus; Estrous cycle; Cyclin's D; cdk4; cdk6; Estrogen receptor; c-fos;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors

Keywords: Cyclin-dependant kinase inhibitor; CDK2; CDK4; VEGFR-2; GSK3β; Pyrazolo[1,5-b] pyridazine; Cancer

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation

Keywords: CAR, constitutive androstane receptor; CDK, cyclin-dependent kinase; PXR, pregnane X receptor; RXR, retinoid X receptor; UGT, UDP-glucuronosyltransferaseCAR; CDK4; MDM2; Cell proliferation; HGF; UGT1A1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Manganese chloride-induced G0/G1 and S phase arrest in A549 cells

Keywords: Manganese chloride; Cell cycle; Cdk2; Cdk4; p53; A549 cells

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Regulation of apoptotic and growth inhibitory activities of C/EBPα in different cell lines

Keywords: C/EBP; Proliferation; Apoptosis; NIH3T3; 3T3-L1; Cyclin D3; cdk4

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

A French CDK4-positive melanoma family with a co-inherited EDNRB mutation

Keywords: Melanoma genetics; CDK4; EDNRB;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Mip/LIN-9 can inhibit cell proliferation independent of the pocket proteins

Keywords: Mip/LIN-9; Retiboblastoma; Pocket proteins; Cell cycle; CDK4

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Mitotic regulation of CDK4 by the serine/threonine phosphatase, calcineurin

Keywords: Calcineurin; CDK4; Mitosis; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Biología molecular de los glioblastomas

Keywords: Glioblastoma; Biología molecular; ADN; ácido desoxiribonucleico; CDK4; quinasa 4 dependiente de ciclina; DMBT1; Deleted in Malignant Brain Tumors; EGF; factor del crecimiento epidérmico; EGFR; receptor del factor del crecimiento epidérmico; EGFR vIII;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Proteomic co-expression of cyclin-dependent kinases 1 and 4 in human cancer cells

Keywords: Cyclin-dependent kinase; Cdk1; Cdk4; Western blotting; Cell lines; Human; Cancer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Cell cycle molecules define a pathway required for neuron death in development and disease

Keywords: Neuron death; Apoptosis; Cell cycle; Cdk4; Myb; Bim

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

3D-QSAR and molecular docking study on bisarylmaleimide series as glycogen synthase kinase 3, cyclin dependent kinase 2 and cyclin dependent kinase 4 inhibitors: An insight into the criteria for selectivity

Keywords: GSK3; CoMFA; QSAR; CDK2; CDK4

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

New potential inhibitors of cyclin-dependent kinase 4: Design and synthesis of pyrido[2,3-d]pyrimidine derivatives under microwave irradiation

Keywords: Pyrido[2,3-d]pyrimidine; Microwave irradiation; Cdk4;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure

Keywords: CDK inhibitor; CDK1; CDK2; CDK4; CDK6; X-ray; CDK4 mimic CDK4; E2F

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

The value of MDM2 and CDK4 amplification levels using real-time polymerase chain reaction for the differential diagnosis of liposarcomas and their histologic mimickers

Keywords: Liposarcoma; MFH; MDM2; CDK4; Real-time PCR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Inactivation of TGF-β signaling in lung cancer results in increased CDK4 activity that can be rescued by ELF

Keywords: ELF; Lung cancer; CDK4; Cell cycle

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Cell cycle deregulation and loss of stem cell phenotype in the subventricular zone of TGF-β adaptor elf−/− mouse brain

Keywords: TGF-β; Smad; cdk4; Cyclin D1; mdm2; p21; pRb

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه