دانلود مقالات ISI درباره CDR، منطقه تعریف مکمل + ترجمه فارسی

گسترش ظرفیت خنثی سازی یک خانواده از قطعات آنتی بادی علیه سموم مختلف از عقرب های مکزیکی

Broadening the neutralizing capacity of a family of antibody fragments against different toxins from Mexican scorpions

Keywords: CDR، منطقه تعریف مکمل; Cross reactivity; Human scFvs; Phage display; Scorpion toxin neutralizationscFv, single chain antibody fragment; CDR, complementarity determining region; FW, framework region; VL, light chain variable domain; VH, heavy chain variable domain; C. noxius, Ce

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

مطالعات تخریبی اجباری از مواد بیولوژیک: انتخاب شرایط تنش

Forced degradation studies of biopharmaceuticals: Selection of stress conditions

Keywords: CDR، منطقه تعریف مکمل; BPTI, bovine pancreatic trypsin inhibitor; CDR, complementarity determining region; CE, capillary electrophoresis; CZE, capillary zone electrophoresis; DKP, diketopiperazine; DTT, dithiothreitol; Fab, antigen binding fragment of a monoclonal antibody; Fc,

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

ساختار آنتی بادی کاتالیستی تجزیه کننده متخلخل متیل

Metal-dependent amyloid β-degrading catalytic antibody construct

Keywords: CDR، منطقه تعریف مکمل; AD, Alzheimer's disease; Aβ, amyloid β peptide; Aβ42, Aβ1-42; Aβ40, Aβ1-40; APP, Aβ precursor protein; BBB, blood–brain barrier; catabody, catalytic antibody; CDR, complementarity determining region; CAA, cerebral amyloid angiopathy; CHAPS, 3-[(3-cholamid

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

آزادی کنترل از فرم های آنتی بادی درمان

Controlled release of therapeutic antibody formats

Keywords: CDR، منطقه تعریف مکمل; ADC, Antibody-drug conjugates; ADCC, Antibody-dependent cellular cytotoxicity; AMD, Age-related macular degeneration; bFGF, basic Fibroblast Growth Factor; CDC, Complement dependent cytotoxicity; CDR, Complementarity determining region; CNS, Central Nervo

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Generating conformation-specific synthetic antibodies to trap proteins in selected functional states

Keywords: CDR، منطقه تعریف مکمل; sAB, synthetic antibody; CDR, complementarity determining region; ELISA, enzyme linked immunosorbent assay; PTM, post translational modification; WT, wild-type; CMC, critical micelle concentration; ChIP, chromatin immunoprecipitationSynthetic antibody; Ph

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Protein selection using yeast surface display

Keywords: CDR، منطقه تعریف مکمل; FACS, fluorescence activated cell sorting; scFv, single chain variable fragment; KD, equilibrium dissociation constant; scTCR, single chain T-cell receptors; CDR, complementarity determining region; 10 Fn3, tenth domain of human fibronectin III; GFP, gree

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Deep sequencing of phage display libraries to support antibody discovery

Keywords: CDR، منطقه تعریف مکمل; aa, amino acid; CDR, Complementarity Determining Region; CDRH3, CDR3 of heavy chain variable region; CDRL3, CDR3 of light chain variable region; Fab, Fragment antigen binding; FR, Framework; hIFNγ, human Interferon γ; IMGT, international ImMunoGeneTics in

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Robust in vitro affinity maturation strategy based on interface-focused high-throughput mutational scanning

Keywords: CDR، منطقه تعریف مکمل; Kd, equilibrium dissociation constant; CDR, complementarity determining region; TNFaR, tumor necrosis factor-alpha receptor; PCR, polymerase chain reactions; PURE system, reconstituted in vitro translation system; Fab-PRD, pure ribosome display in single-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

A strategy for phage display selection of functional domain-exchanged immunoglobulin scaffolds with high affinity for glycan targets

Keywords: CDR، منطقه تعریف مکمل; Fab, antigen binding fragment; CDR, complementarity determining region; VL, light chain variable domain; CL, light chain constant domain; VH, heavy chain variable domain; CH, heavy chain constant domain; ss-dU-DNA, single-stranded uridine-enriched DNA; PB

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Targeting epidermal growth factor receptor in tumors: From conventional monoclonal antibodies via heavy chain-only antibodies to nanobodies

Keywords: CDR، منطقه تعریف مکمل; ADCC, antibody dependent cellular cytotoxicity; Au NP, gold nanoparticles; BSH, sodium borocaptate; CDC, complement dependent cytotoxicity; CDR, complementarity determining region; DDS, drug delivery system; DOX, doxorubicin; EGFR, epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Clinical immunogenicity specificity assessments: A platform evaluation

Keywords: CDR، منطقه تعریف مکمل; ATA, anti-therapeutic antibody; CDR, complementarity determining region; DIG, digoxigenin; ECLA, electrochemiluminescence assay; ECLU, electrochemiluminescent unit; ELISA, enzyme-linked immunosorbent assay; MSD, Meso Scale Discovery; IgG, immunoglobulin g

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Structure of the Fab fragment of the anti-murine EGFR antibody 7A7 and exploration of its receptor binding site

Keywords: CDR، منطقه تعریف مکمل; CCP4, Collaborative Computational Project, Number 4; CDR, complementarity determining region; CH, heavy chain constant domain; CL, light chain constant domain; EDTA, ethylene diamine tetraacetate; eEGFR, the extracellular domain of the human EGFR; EGF, ep

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Increased rheumatoid factor interference observed during immunogenicity assessment of an Fc-engineered therapeutic antibody

Keywords: CDR، منطقه تعریف مکمل; ATA, anti-therapeutic antibody; CDR, complementarity determining region; DIG, digoxigenin; ELISA, enzyme-linked immunosorbent assay; FcRn, neonatal Fc receptor; IgG, immunoglobulin gamma; RA, rheumatoid arthritis; RF, rheumatoid factorAnti-CD4; Anti-thera

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Single-chain Fv fragment antibodies selected from an intrabody library as effective mono- or bivalent reagents for in vitro protein detection

Keywords: CDR، منطقه تعریف مکمل; scFv, single-chain Fv; VH, variable heavy chain domain; VL, variable light chain domain; CDR, complementarity determining region; EGFP, enhanced green fluorescent protein; GFPuv, green fluorescent protein variant visible under UV light; GK, gankyrin; MBP,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Integrin binding human antibody constant domains—Probing the C-terminal structural loops for grafting the RGD motif

Keywords: CDR، منطقه تعریف مکمل; mAb, monoclonal antibody; IgG1-Fc, crystallizable fragment of immunoglobulin G class 1; CDR, complementarity determining region; Fcab, antigen binding crystallizable domain; wt, wild-type; ADCC, antibody-dependent cellular cytotoxicity; CDC, complement-de

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Expression and genomic analyses of Camelus dromedarius T cell receptor delta (TRD) genes reveal a variable domain repertoire enlargement due to CDR3 diversification and somatic mutation

Keywords: CDR، منطقه تعریف مکمل; TRD, T cell receptor delta; IG, immunoglobulin; CDR, complementarity determining region; FR, framework region; V, variable; J, joining; cDNA, complementary DNA; RACE, rapid amplification of cDNA ends; RT-PCR, reverse transcription-polymerase chain reactio

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Generation and validation of canine single chain variable fragment phage display libraries

Keywords: CDR، منطقه تعریف مکمل; CDR, complementarity determining region; CPV, canine parvovirus; CSCG, Canine Single Chain Gamma; CSCJK, Canine Single Chain Joining Kappa; CSCJLam, Canine Single Chain Joining Lambda; CSCK, Canine Single Chain Kappa; CSCLam, Canine Single Chain Lambda; C

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

The pre-B cell receptor checkpoint

Keywords: CDR، منطقه تعریف مکمل; aa, amino acids; BCR, B cell receptor; CD, cluster of differentiation; CDR, complementarity determining region; D, diversity; H chain, heavy chain; Ig, immunoglobulin; J, joining; L chain, light chain; λ5 T, λ5-deficient mice; λ5-UR, λ5 unique region; μMT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

A large human domain antibody library combining heavy and light chain CDR3 diversity

Keywords: CDR، منطقه تعریف مکمل; VH, heavy chain variable domain; VL, light chain variable domain; dAb, domain antibody; Fab, antigen-binding fragment; CDR, complementarity determining region; L3, light chain CDR3; H2, heavy chain CDR2; H3, heavy chain CDR3; FR, framework region; KL, kap

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Dissection of the IgNAR V Domain: Molecular Scanning and Orthologue Database Mining Define Novel IgNAR Hallmarks and Affinity Maturation Mechanisms

Keywords: CDR، منطقه تعریف مکمل; CDR, complementarity determining region; HRP, horseradish peroxidase; PBS, phosphate-buffered saline; HBS-P, Hepes-buffered saline phosphate; RU, response units; Fw, framework; HEL, hen egg lysozyme; HV, hypervariable region; TCR, T-cell receptor; PBS-MB,

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Somatic hypermutation in peritoneal B1b cells

Keywords: CDR، منطقه تعریف مکمل; AICDA, activation-induced cytidine deaminase; CDR, complementarity determining region; ELISPOT, enzyme-linked immunospot technique; H chain, heavy chain; L chain, light chain; LPS, lipopolysaccharide; mRNA, messenger RNA; RT-PCR, reverse transcriptase pol

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

A machine-learning approach for predicting B-cell epitopes

Keywords: CDR، منطقه تعریف مکمل; ASA, accessible surface area; AUC, area under the curve; CDR, complementarity determining region; CEP, Conformational Epitope Prediction; PDB, protein data bank; ROC, receiver operating characteristic; 3D, 3-dimensionalAntigen; Antibody; Epitope; Immunoge

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Generation of Immunoglobulin diversity in human gut-associated lymphoid tissue

Keywords: CDR، منطقه تعریف مکمل; AID, activation-induced cytidine deaminase; APRIL, A-proliferation and inducing ligand; BAFF, B cell-activating factor belonging to the TNF family; BCMA, B-cell maturation antigen; CDR, complementarity determining region; D, diversity region; DC, dendriti

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Complementarity determining regions of an anti-prion protein scFv fragment orchestrate conformation specificity and antiprion activity

Keywords: CDR، منطقه تعریف مکمل; aFFF, asymmetric field-flow fractionation; BBB, blood–brain barrier; CD, circular dichroism; CDR, complementarity determining region; CDR3H, third CDR of the heavy chain; (d-)riCDR3H, retro-inverso d-peptide analogue to CDR3H; NHS, N-hydroxysuccinimide; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

A single-step procedure of recombinant library construction for the selection of efficiently produced llama VH binders directed against cancer markers

Keywords: CDR، منطقه تعریف مکمل; CDR, complementarity determining region; ELISA, enzyme-linked immunosorbent assay; FR, framework region; GST, glutathione S-transferase; IgG, immunoglobulin G; KD, equilibrium dissociation constant; MPBST, milk phosphate-buffered saline-Tween 20; PCR, pol

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Structural Insights into Immune Recognition of the Severe Acute Respiratory Syndrome Coronavirus S Protein Receptor Binding Domain

Keywords: CDR، منطقه تعریف مکمل; SARS-CoV, severe acute respiratory syndrome coronavirus; S, spike; RBD, receptor binding domain; RBM, receptor binding motif; ACE2, angiotensin-converting enzyme 2; CDR, complementarity determining region; EDTA, ethylenediaminetetraacetic acidimmune recog

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

A model for the development of human IgD-only B cells: Genotypic analyses suggest their generation in superantigen driven immune responses

Keywords: CDR، منطقه تعریف مکمل; PB, peripheral blood; BCR, B cell receptor; FR, framework region; CDR, complementarity determining region; GC, germinal center; R/S, replacement versus silent mutations; MID, Moraxella IgD binding proteinClonality; IgD; Memory B cells; Somatic hypermutati

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

A new method to discriminate immunogen-specific heavy-chain homodimer from heterotetramer immunoglobulin G directly in immunized dromedary whole plasma proteins: Western ligand blotting

Keywords: CDR، منطقه تعریف مکمل; aa, amino acid; CDR, complementarity determining region; DLB, dot ligand blotting; Fab, antigen-binding fragment of an antibody; HC IgG, heavy-chain only immunoglobulin G; IgG, immunoglobulin G; kDa, kilo Dalton; LC–MS/MS, liquid chromatography mass spect

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Antibody production, design and use for biosensor-based applications

Keywords: CDR، منطقه تعریف مکمل; Ab, antibody; Ag, antigen; AP, alkaline phosphatase; ARM, antibody–ribosome–mRNA; BSA, bovine serum albumin; BW, bulk wave; CDR, complementarity determining region; CH, constant heavy chain (1, 2 and 3); DNA, deoxyribonucleic acid; DTT, dithiothreitol; Fa

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2009 سفارش ترجمه

Improvement of an Antibody Neutralizing the Anthrax Toxin by Simultaneous Mutagenesis of Its Six Hypervariable Loops

Keywords: CDR، منطقه تعریف مکمل; Fab, antigen-binding fragment; LT, lethal toxin; PA, protective antigen; CDR, complementarity determining region; VH, heavy chain variable domain; VL, light chain variable domain; Kd, dissociation constant; IC50, 50% inhibitory concentration; koff, dissoc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Killer T cells in influenza

Keywords: CDR، منطقه تعریف مکمل; BAL, Brochoalveolar lavage; B6, C57.BL/6J (H-2b); CTL, Cytotoxic lymphocyte; CDR, complementarity determining region; DbNP366, epitope consisting of NP amino acid residues 366-374 + MHC Class I glycoprotein H-2Db; DbPA244, epitope consisting of PA amino a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Amyloid-β–Anti-Amyloid-β Complex Structure Reveals an Extended Conformation in the Immunodominant B-Cell Epitope

Keywords: CDR، منطقه تعریف مکمل; Aβ, peptide associated with Alzheimer's disease; AD, Alzheimer's disease; CDR, complementarity determining region; L1–3, light-chain CDR 1–3; H1–3, heavy-chain CDR 1–3; mAb, monoclonal antibody; r.m.s.d., root-mean-square deviation; WO2, antibody raised a

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Characterization of C-, J- and V-region-genes of the feline T-cell receptor γ

Keywords: CDR، منطقه تعریف مکمل; V, variable; D, diversity; J, joining; RAG, recombination activating gene; FR, framework region; CDR, complementarity determining region; TRD, T-cell receptor δ; TRG, T-cell receptor γ; TRA, T-cell receptor α; TRB, T-cell receptor β; fTRG, feline T-cell r

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Computational characterization of B-cell epitopes

Keywords: CDR، منطقه تعریف مکمل; APBS, adaptive Poisson–Boltzmann solver; ASA, accessible surface area; CDR, complementarity determining region; CE, combinatorial extension; CGAL, computational geometry algorithms library; CSU, contacts of structural units; DSSP, dictionary of secondary

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular modeling of the complex between Torpedo acetylcholine receptor and anti-MIR Fab198

Keywords: CDR، منطقه تعریف مکمل; AChBP, acetylcholine-binding protein; AChR, acetylcholine receptor; ASA, accessible surface area; CDR, complementarity determining region; ECD, extracellular domain; MIR, main immunogenic region; MG, myasthenia gravis; mAb, monoclonal antibodyNicotinic ac

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

New display vector reduces biological bias for expression of antibodies in E. coli

Keywords: CDR، منطقه تعریف مکمل; aa, amino acid(s); AP, alkaline phosphatase; Ap, ampicillin; CDR, complementarity determining region; CEA, carcinoembryonic antigen; GST, glutathione S-transferase; HC, heavy chain; HRP, horseradish peroxidase; IPTG, isopropyl b-d-thiogalactopyranoside; K

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells

Keywords: CDR، منطقه تعریف مکمل; AID, activation induced cytidine deaminase; CDR, complementarity determining region; FR, framework region; Ig, immunoglobulin; PBMC, peripheral blood mononuclear cell; R, replacement mutation; RAG, recombinase activating genes; S, silent mutation; TdT, te

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Crystal Structure of a Human Autoimmune Complex between IgM Rheumatoid Factor RF61 and IgG1 Fc Reveals a Novel Epitope and Evidence for Affinity Maturation

Keywords: CDR، منطقه تعریف مکمل; CDR, complementarity determining region; FCS, fetal calf serum; Ig, immunoglobulin; RA, rheumatoid arthritis; RF, rheumatoid factors; PBS, phosphate-bufferred saline; SpA, Staphylococcus aureus protein Aautoantibody; autoantigen; rheumatoid factor; autoim

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Chimeric rabbit/human Fab and IgG specific for members of the Nogo-66 receptor family selected for species cross-reactivity with an improved phage display vector

Keywords: CDR، منطقه تعریف مکمل; CNS, central nervous system; mAb, monoclonal antibody; GPI, glycosylphosphatidyl-inositol; LRR, leucine-rich repeat; MAG, myelin associated glycoprotein; OMgp, oligodendrocyte myelin glycoprotein; CDR, complementarity determining region; FR, framework reg

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

An Anti-urokinase Plasminogen Activator Receptor (uPAR) Antibody: Crystal Structure and Binding Epitope

Keywords: CDR، منطقه تعریف مکمل; CDR, complementarity determining region; PEG, polyethylene glycol; uPA, urokinase-type plasminogen activator; ATF, the amino-terminal fragment of uPA; uPAR, urokinase-type plasminogen activator receptor; suPAR, soluble uPARantibody; crystal structure; uPA

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Specific Recognition of a DNA Immunogen by its Elicited Antibody

Keywords: CDR، منطقه تعریف مکمل; ss, single-stranded; ds, double-stranded; mAb, monoclonal antibody; CDR, complementarity determining region; SLE, Systemic Lupus Erythematosus; HPV, human papillomavirus; E2c, C-terminal domain of E2 protein from HPVanti-DNA; structure; antibody; autoimmu

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Single MHC Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding

Keywords: CDR، منطقه تعریف مکمل; MHC, major histocompatibility complex; TCR, T cell receptor; pMHC, peptide bound to MHC; CDR, complementarity determining region; SPR, surface plasmon resonance; ITC, isothermal titration calorimetryMHC; TCR; binding; structure; cytolysis

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Cloning, sequence analysis and confirmation of derived gene sequences for three epitope-mapped monoclonal antibodies against human phagocyte flavocytochrome b

Keywords: CDR، منطقه تعریف مکمل; BME, 2-mercaptoethanol; CDR, complementarity determining region; Cyt b, human phagocyte flavocytochrome b; DTT, dithiothreitol; EDTA, ethylenediaminetetraacetic acid; ESI, electrospray ionization; FAD, flavin adenine dinucleotide; FR1, framework 1; IPTG,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

High-throughput Generation of Synthetic Antibodies from Highly Functional Minimalist Phage-displayed Libraries

Keywords: CDR، منطقه تعریف مکمل; phage display; protein engineering; combinatorial mutagenesis; antibody library; vascular endothelial growth factorBSA, bovine serum albumin; CDR, complementarity determining region; CDR-Hn, (where n = 1, 2, or 3), heavy chain CDR 1, 2, or 3; CDR-L3, ligh

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

Antibody internalization studied using a novel IgG binding toxin fusion

Keywords: CDR، منطقه تعریف مکمل; CDR, complementarity determining region; DMF, Dimethyl Formamide; ELISA, enzyme-linked immunosorbent assay; FCS, fetal calf serum; FITC, fluorescein isothiocyanate; mAb, monoclonal antibody; FPLC, fast protein liquid chromatography; HRP, horseradish perox

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2007 سفارش ترجمه

Crystal Structure of the TCR Co-receptor CD8αα in Complex with Monoclonal Antibody YTS 105.18 Fab Fragment at 2.88 Å Resolution

Keywords: CDR، منطقه تعریف مکمل; CD8; X-ray structure; antibody structure; T-cell; immune systemIgSF, immunoglobulin super-family; MHC, major histocompatibility complex; IEL, intra-epithelial leucocytes; TL, thymic leukaemia antigen; CDR, complementarity determining region

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Molecular analysis of anti-N-propionyl Neisseria meningitidis group B polysaccharide monoclonal antibodies

Keywords: CDR، منطقه تعریف مکمل; 3D, three dimensional; CDR, complementarity determining region; Dp, degree of polymerization; Fv, antibody fragment variable; MBPS, meningococcal group B polysaccharide; MCPS, meningococcal group C polysaccharide; N-Ac MBPS, N-acetyl MBPS; N-Pr MBPS, N-pr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Antibody repertoire development in the sheep

Keywords: CDR، منطقه تعریف مکمل; B lymphocytes; Immunoglobulins; Repertoire development; Germline repertoire; Gene rearrangement; Junctional diversity; Somatic hypermutation; Ileal Peyer's patchAg, antigen; C, immunoglobulin constant gene segment; CDR, complementarity determining region;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Unveiling molecular mechanisms of pneumococcal surface protein A interactions with antibodies and lactoferrin

Keywords: CDR، منطقه تعریف مکمل; 3D, three-dimensional; aa, amino acid; CBD(s), choline-binding domain(s); CBP, choline-binding protein; CD, circular dichroism; CDR, complementarity determining region; ELISA, enzyme linked immunosorbent assays; Fab, Fab part of antibody; hLf, human lacto

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Affinity maturation of phage display antibody populations using ribosome display

Keywords: CDR، منطقه تعریف مکمل; CDR, complementarity determining region; VH, heavy chain variable domain; VL, light chain variable domain; Kd, dissociation equilibrium constant; kd, dissociation kinetic rate constant; ka, association kinetic rate constant; TNF, tumour necrosis factor; I

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه