Keywords: سلسترول; Celastrol; Retina; Ganglion cells; Optic nerve; Glaucoma; Neuroprotection;
مقالات ISI سلسترول (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: سلسترول; Breast cancer; Celastrol; Folic acid; Irinotecan; Liposomes;
Keywords: سلسترول; Preeclampsia; Hypertension; Blood pressure; Celastrol; Matrix metalloproteinase;
Keywords: سلسترول; Celastrol; Apoptosis; Cell cycle arrest; Antiproliferation; Antimetastasis; Anti-inflammation; Antioxidant;
Keywords: سلسترول; Celastrol; C-3 hydroxyl derivatives; Cytotoxicity; In vivo activity; Intragastric administration;
Keywords: سلسترول; Triterpenoids; Celastrol; Urea derivatives; Anticancer activity; Apoptosis; Drug synergy;
Keywords: سلسترول; Rheumatoid arthritis; Neutrophils; Celastrol;
Keywords: سلسترول; Celastrol; Milk-derived exosomes; Drug delivery; Lung cancer
Keywords: سلسترول; Axitinib; Celastrol; Mitochondria; Mesoporous silica nanoparticle; Lipid
Keywords: سلسترول; Celastrol; Necroptosis; MLKL; RIP3; Ulcerative colitis;
Keywords: سلسترول; Celastrol; ER stress; Unfolded protein response; Oral cancer; Apoptosis; Drug discovery; Chaperone; Protein folding;
Keywords: سلسترول; Colitis; Intestinal homeostasis; Celastrol; Inflammasome
Keywords: سلسترول; Celastrol; Solid self-microemulsifying system (S-SMEDDS); Dispersible tablets; Oral bioavailability;
Keywords: سلسترول; Celastrol; Human cervical cancer cell; Apoptosis; Gas chromatography-mass spectrometry; Metabolic profiling; Metabolomics;
Keywords: سلسترول; Celastrol; Tight junction proteins; Oxygen glucose deprivation; Signal transduction; Blood-brain barrier; CNS; central nervous system; MAPKs; mitogen-activated protein kinases; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase; PI3K
Celastrol inhibits cancer metastasis by suppressing M2-like polarization of macrophages
Keywords: سلسترول; Celastrol; Macrophage; Polarization; Cancer metastasis;
Role of c-Myb in the regulation of natural killer cell activity
Keywords: سلسترول; Natural killer cells; Interleukin-2; Transforming growth factor-beta; c-Myb; Celastrol;
Overexpression and RNAi-mediated downregulation of TwIDI regulates triptolide and celastrol accumulation in Tripterygium wilfordii
Keywords: سلسترول; Tw; Tripterygium wilfordii; OE; overexpression; RNAi or Ri; RNA interference; IDI; isopentenyl diphosphate isomerase; CDS; coding sequence; TwIDI; Overexpression; RNAi; Triptolide; Celastrol; Gene gun;
Effect of celastrol on the progression of polycystic kidney disease in a Pkd1-deficient mouse model
Keywords: سلسترول; Inflammation; Polycystic kidney disease; Celastrol; Macrophage;
Celastrol mediates Th17 and Treg cell generation via metabolic signaling
Keywords: سلسترول; Celastrol; T helper 17â¯cell; Induced regulatory T cells; Glycolysis; Fatty acid β-oxidation;
Celastrol pretreatment attenuates rat myocardial ischemia/ reperfusion injury by inhibiting high mobility group box 1 protein expression via the PI3K/Akt pathway
Keywords: سلسترول; Celastrol; Myocardial ischemia/reperfusion injury; Protective effect; PI3K/Akt;
Celastrol attenuates incision-induced inflammation and pain associated with inhibition of the NF-κB signalling pathway via SARM
Keywords: سلسترول; Celastrol; Incision; Inflammation; Pain; NF-κB; SARM;
Therapeutic targeting of PP2A
Keywords: سلسترول; Protein phosphatase 2A; PP2A; SET; CIP2A; PME-1; LCMT-1; FTY720; OP449; Bortezomib; Erlotinib; Celastrol; ABL-127; SMAPs; Phenothiazines; LB-100; Protein phosphatases; Drug development; Cancer; Cell signaling; Tumor suppressors;
PEGylated polyaminoacid-capped mesoporous silica nanoparticles for mitochondria-targeted delivery of celastrol in solid tumors
Keywords: سلسترول; Celastrol; Mesoporous silica nanoparticles; Mitochondria targeting; Cancer therapy; HIF-1α inhibition;
A new mechanism of inhibition of IL-1β secretion by celastrol through the NLRP3 inflammasome pathway
Keywords: سلسترول; Celastrol; Anti-inflammatory effects; NLRP3 inflammasome; IL-1β;
Celastrol inhibits dengue virus replication via up-regulating type I interferon and downstream interferon-stimulated responses
Keywords: سلسترول; Dengue virus; Celastrol; Antiviral interferon response;
Celastrol attenuates angiotensin II mediated human umbilical vein endothelial cells damage through activation of Nrf2/ERK1/2/Nox2 signal pathway
Keywords: سلسترول; Celastrol; Angiotensin II; Reactive oxygen species; Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase; Nuclear factor erythroid 2-related factor 2; Nox2;
Celastrol inhibits hepatitis C virus replication by upregulating heme oxygenase-1 via the JNK MAPK/Nrf2 pathway in human hepatoma cells
Keywords: سلسترول; HCV; Celastrol; Heme oxygenase 1; JNK mitogen-activated protein kinase;
Original ArticleCelastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1
Keywords: سلسترول; Nonalcoholic fatty liver disease; Celastrol; Sirt1; Lipid metabolism; Chronic inflammation; Oxidative stress;
Celastrol attenuates mitochondrial dysfunction and inflammation in palmitate-mediated insulin resistance in C3A hepatocytes
Keywords: سلسترول; Celastrol; Mitochondrial dysfunction; Inflammation; Insulin resistance; Hepatocytes;
Celastrol reduces IL-1β induced matrix catabolism, oxidative stress and inflammation in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration in vivo
Keywords: سلسترول; NF-κB; Inflammation; Celastrol; Intervertebral disc degeneration;
Design, synthesis and biological evaluation of novel C-29 carbamate celastrol derivatives as potent and selective cytotoxic compounds
Keywords: سلسترول; Celastrol; Triterpenes; Carbamates; Cytotoxicity; Apoptosis; Drug synergy;
Autophagy induction by celastrol augments protection against bleomycin-induced experimental pulmonary fibrosis in rats: Role of adaptor protein p62/ SQSTM1
Keywords: سلسترول; Autophagy; Pulmonary fibrosis; p62; Celastrol; Bleomycin; mTOR; AEC; Alveolar epithelial cell; Atg; Autophagy-related; BLM; Bleomycin; DMSO; Dimethyl sulfoxide; FITC; Fluorescein isothiocyanate; IgG; Immunoglobulin G; IL; interleukin; Keap1; Kelch-Like EC
Celastrol inhibits chondrosarcoma proliferation, migration and invasion through suppression CIP2A/c-MYC signaling pathway
Keywords: سلسترول; Chondrosarcoma; Celastrol; CIP2A; c-MYC;
Celastrol targets IRAKs to block Toll-like receptor 4-mediated nuclear factor-κB activation
Keywords: سلسترول; celastrol; interleukin-1 receptor-associated kinases; nuclear factor-kappa B; Toll-like receptor 4; hepatocytes;
Downregulation of miR-17-92a cluster promotes autophagy induction in response to celastrol treatment in prostate cancer cells
Keywords: سلسترول; miR-17-92a; Autophagy; Celastrol; Prostate cancer; Androgen receptor;
Celastrol, an NF-κB inhibitor, ameliorates hypercalciuria and articular cartilage lesions in a mouse model of secondary osteoporosis
Keywords: سلسترول; Celastrol; NF-κB inhibitor; Secondary osteoporosis; Cartilage lesions
Cascade regulation of PPARγ2 and C/EBPα signaling pathways by celastrol impairs adipocyte differentiation and stimulates lipolysis in 3T3-L1 adipocytes
Keywords: سلسترول; Celastrol; Adipocytes differentiation; Lipolysis; PPARγ2; C/EBPα
Resveratrol, piperine and apigenin differ in their NADPH-oxidase inhibitory and reactive oxygen species-scavenging properties
Keywords: سلسترول; NADPH oxidase (NOX); Antioxidant; Reactive oxygen species; Celastrol; Resveratrol; B-LCL; B-lymphoblastoid cell line; CMV; cytomegalovirus; DMSO; dimethyl sulfoxide; DPI; diphenyleneiodonium; EBV; Epstein-Barr virus; EDTA; Ethylenediaminetetraacetic acid;
Celastrol enhances Nrf2 mediated antioxidant enzymes and exhibits anti-fibrotic effect through regulation of collagen production against bleomycin-induced pulmonary fibrosis
Keywords: سلسترول; Pulmonary fibrosis; Celastrol; Bleomycin; Collagen; Phase II enzymes; Nrf2
Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A2 group IIA, 5-lipoxygenase and cyclooxygenase-2
Keywords: سلسترول; AA; arachidonic acid; COX; cyclooxygenase; LOX; lipoxygenase; sPLA2IIA; secretory phospholipase A2 group IIA; Inflammation; Arachidonic acid; Cyclooxygenase; Lipoxygenase; Phospholipase A2; Celastrol;
Optimization and biological evaluation of celastrol derivatives as Hsp90-Cdc37 interaction disruptors with improved druglike properties
Keywords: سلسترول; Celastrol; Hsp90-Cdc37 interaction; HTRF; Structure-activity relationship; Druglike properties;
Inhibition of inflammation with celastrol fails to improve muscle function in dysferlin-deficient A/J mice
Keywords: سلسترول; Muscular dystrophy; Skeletal muscle; Dysferlin; Celastrol; NF-κB; Inflammation;
Celastrol attenuates bone erosion in collagen-Induced arthritis mice and inhibits osteoclast differentiation and function in RANKL-induced RAW264.7
Keywords: سلسترول; ALT; aminotransferase; CIA; collagen-Induced arthritis; Ctr; calcitonin receptor; Ctsk; cathepsin K; CM; culture medium; MAPK; mitogen-activated protein kinases; Mmp-9; matrix metallopeptidase 9; M-CSF; macrophage colony-stimulating factor; IP; intraperit
Research PaperCelastrol prevents circulatory failure via induction of heme oxygenase-1 and heat shock protein 70 in endotoxemic rats
Keywords: سلسترول; Celastrol; Sepsis; Circulatory failure; Heme oxygenase-1; Heat shock protein 70;
Celastrol ameliorates experimental colitis in IL-10 deficient mice via the up-regulation of autophagy
Keywords: سلسترول; Colitis; Celastrol; Autophagy; Inflammation
Celastrol supports survival of retinal ganglion cells injured by optic nerve crush
Keywords: سلسترول; Celastrol; Retina; Ganglion cells; Optic nerve; Neuroprotection
Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ
Keywords: سلسترول; Celastrol;; Chinese medicine;; Experimental arthritis;; Rheumatoid arthritis;; T helper 17 cells;; T regulatory cells;; Immune regulation;
Anticancer effect of celastrol on human triple negative breast cancer: Possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways
Keywords: سلسترول; Celastrol; TNBC; Oxidative stress; Mitochondrial dysfunction; Apoptosis; PI3K/Akt;
Sugar-decorated mesoporous silica nanoparticles as delivery vehicles for the poorly soluble drug celastrol enables targeted induction of apoptosis in cancer cells
Keywords: سلسترول; Targeted drug delivery; Celastrol; Surface functionalization; Mesoporous silica nanoparticles; Glucose consumption; Cancer therapy;