
Relevance of the mouse model as a therapeutic approach for neutrophil proteinase 3-associated human diseases
Keywords: hPR3, human proteinase 3; mPR3, mouse proteinase 3; hNE, human neutrophil elastase; CG, cathepsin G; MPO, myeloperoxidase; NSPs, neutral serine proteinases; αl-PI, α1-proteinase inhibitor; P21, cyclin-dependent kinase inhibitor-1; ANCA, antineutrophil cyt