Keywords: ChE، کولین استراز; Acetylcholinesterase; Butyrylcholinesterase; Slow-binding inhibition; Tight-binding inhibition; Residence timeAChE, acetylcholinesterase; BChE, butyrylcholinesterase; ChE, cholinesterase; CSP, cresyl saligenin phosphate; DFP, diisopropylfluorophosphate; D
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Keywords: ChE، کولین استراز; ChEs, cholinesterases; BChE, butyrylcholinesterase; AChE, acetylcholinesterase; ChE, cholinesterase; OP, organophosphates; PP, pulverization period; RP, recess period; ACh, acetylcholine; ASCh, acetylthiocholine iodide; BSCh, butyrylthiocholine iodide; is
Keywords: ChE، کولین استراز; ChE, cholinesterase; ATPase, adenosine triphosphatase; CE, carboxylesterase; GST, glutathione-S-transferase; ACP, acid phosphatase; ALP, alkaline phosphatase; AST, aspartate aminotransferase; ALT, alanine aminotransferaseRelative organ weight; Non target
Keywords: ChE، کولین استراز; Alzheimer's disease; Cholinesterase inhibitors; Coumarin; Tacrine; β-Amyloid aggregation; CholinesteraseAD, Alzheimer's disease; ACh, acetylcholine; CNS, central nervous system; ChE, cholinesterase; ChEI, cholinesterase inhibitor; hAChE, human acetylcholi
Keywords: ChE، کولین استراز; BALF, bronchoalveolar lavage fluid; ChE, cholinesterase; MMP-9, matrix-metalloproteinase-9; PBS, phosphate-buffered saline; sPLA2, secretory phospholipase A2; RCA, ricinus communis agglutinin; VEGF, vascular endothelial growth factor; XO, xanthine oxidase
Learning performances and vulnerability to amyloid toxicity in the butyrylcholinesterase knockout mouse
Keywords: ChE، کولین استراز; ACh, acetylcholine; AChE, acetylcholinesterase; AD, Alzheimer’s disease; Aβ, amyloid-β; Aβ25–35, amyloid-β[25–35] peptide; BChE, butyrylcholinesterase; ChE, cholinesterase; CHP, cumene hydroperoxide; HPLC, high-performance liquid chromatography; ICV, intr
Chemical and biological insights on Cotoneaster integerrimus: A new (-)- epicatechin source for food and medicinal applications
Keywords: ChE، کولین استراز; Cotoneaster; (-)-epicatechin; Biological effect; Chemical fingerprint; Molecular docking; NutraceuticalsABTS, 2,2’-azino-bis(3-ethylbenzothiazoline)-6-sulfonic acid; AChE, acetylcholinesterase; BChE, butyrylcholinesterase; ChE, Cholinesterase; CUPRAC, Cup
Resistance in cholinesterase activity after an acute and subchronic exposure to azinphos-methyl in the freshwater gastropod Biomphalaria straminea
Keywords: ChE، کولین استراز; AcSCh, acetylthiocholine iodide; BuSCh, butyrylthiocholine iodide; BW284c51, 1,5-bis(4-allyldimethyl-ammoniumphenyl) pentan-3-one dibromide; CE, carboxylesterase; ChE, cholinesterase; IC50, 50 percent inhibition concentration; DTNB, 5,5′-dithio-2-bis-nitr
Effects of vanadium (III, IV, V)-chlorodipicolinate on glycolysis and antioxidant status in the liver of STZ-induced diabetic rats
Keywords: ChE، کولین استراز; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CAT, catalase; CHE, cholinesterase; dipic, dipicolinate; GK, glucokinase; GSH-Px, glutathione peroxidase; γ-GT, γ-glutamyl transpeptidase; HbA1c, Glycosylated hemog
Antiglioma activity of GoPI-sugar, a novel gold(I)–phosphole inhibitor: Chemical synthesis, mechanistic studies, and effectiveness in vivo
Keywords: ChE، کولین استراز; AP, alkaline phosphatase; BCNU, carmustine; BUN, blood urea nitrogen; CHE, cholinesterase; Cr, creatinine; DMEM, Dulbeco's Modified Eagle Medium; GoPI, 1-phenyl-bis(2-pyridyl)phosphole gold chloride; GoPI-sugar, 1-phenyl-bis(2-pyridyl)phosphole gold chlor
Which acetylcholinesterase functions as the main catalytic enzyme in the Class Insecta?
Keywords: ChE، کولین استراز; Acetylcholinesterase; Evolution; Insect; Functional replacementAChE, acetylcholinesterase; ChE, cholinesterase; BChE, butyrylcholinesterase; OP, organophosphate; CB, carbamate; PAGE, polyacrylamide gel electrophoresis; CNS, central nervous system; RACE, r
Investigation of the neuroprotective action of saffron (Crocus sativus L.) in aluminum-exposed adult mice through behavioral and neurobiochemical assessment
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; ATCh, acetylthiocholine iodide; BuChE, butyrylcholinesterase; BuTCh, butyrylthiocholine iodide; ce, cerebellum; ChE, cholinesterase; DS, detergent-soluble; GSH, reduced glutathione; i.p., intraperitoneal injections; IL, initial
Progress in the development of enzyme-based nerve agent bioscavengers
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; BChE, butyrylcholinesterase; CaE, carboxylesterase; CBDP, 2-(o-cresyl)-4H-1,3,2-benzodioxaphosphoran-2-one or cresyl saligenin phosphate; ChE, cholinesterase; CHO, Chinese hamster ovary; HDL, high density lipoprotein; OPNA, org
Cholinesterases and neurotoxicity as highly sensitive biomarkers for an organophosphate insecticide in a freshwater gastropod (Chilina gibbosa) with low sensitivity carboxylesterases
Keywords: ChE، کولین استراز; ASCh, acetylthiocholine iodide; BSCh, butyrylthiocholine iodide; CAT, catalase; CDNB, 1-chloro-2,4-dinitrobenzene; CE, carboxylesterase; ChE, cholinesterase; IC50, 50% inhibition concentration; DTNB, 5,5′-dithio-2-bis-nitrobenzoate; iso-OMPA, tetraisoprop
Cholinesterase and carboxylesterase inhibition in Planorbarius corneus exposed to binary mixtures of azinphos-methyl and chlorpyrifos
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; AcSCh, acetylthiocholine iodide; AZM, azinphos-methyl; CES, carboxylesterases; ChE, cholinesterase; CPF, chlorpyrifos; DTNB, 5,5′-dithio-2-bis-nitrobenzoate; 1- and 2-NA, 1- and 2-naphthyl acetate; p-NPA, p-nitrophenyl acetate;
Reversible effect of maternal exposure to chlorpyrifos on the intermediate granule cell progenitors in the hippocampal dentate gyrus of rat offspring
Keywords: ChE، کولین استراز; ChE, cholinesterase; CPF, chlorpyrifos; DCX, doublecortin; GABA, γ-aminobutyric acid; GD, gestational day; GFAP, glial fibrillary acidic protein; NAChRα7, nicotinic acetylcholine receptor alpha 7; NeuN, neuron-specific nuclear protein; PCNA, proliferating
Acute exposure to the insecticide O,S-dimethyl phosphoramidothioate (methamidophos) leads to impairment of cardiovascular reflexes in rats
Keywords: ChE، کولین استراز; OP, organophosphorus; MTP, methamidophos; CR, chemoreceptor reflex; BJR, Bezold–Jarisch reflex; AChE, acetylcholinesterase; ChE, cholinesterase; PBG, phenylbiguanide; KCN, potassium cyanide; MAP, mean arterial pressure; HR, heart rate; LD50, median lethal
Postnatal growth hormone deficiency in growing rats causes marked decline in the activity of spinal cord acetylcholinesterase but not butyrylcholinesterase
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; ASChCl, acetylthiocholine chloride; BuChE, butyrylcholinesterase; ChAT, Choline acetyltransferase; ChE, Cholinesterase; CNS, central nervous system; GH, growth hormone; NS, not significant; P, postnatal; SC, spinal cord; SpDwf,
In vivo studies on inhibition and recovery of B-esterase activities in Biomphalaria glabrata exposed to azinphos-methyl: Analysis of enzyme, substrate and tissue dependence
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; AcSCh, acetylthiocholine iodide; BuChE, butyrylcholinesterase; BuSCh, butyrylthiocholine iodide; CES, carboxylesterases; ChE, cholinesterase; DTNB, 5,5′-dithio-2-bis-nitrobenzoate, 1- and 2-NA, 1- and 2-naphthyl acetate; OP, or
Evidence for diazinon-mediated inhibition of cis-permethrin metabolism and its effects on reproductive toxicity in adult male mice
Keywords: ChE، کولین استراز; ChE, cholinesterase; P450scc, cytochrome P450 side-chain cleavage; DEP, diethylphosphate; DETP, diethylthiophosphate; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; 3PBA, 3-phenoxybenzoic acid; StAR, steroidogenic acute regulatory protein; TSPO, translo
Chemical profiling and biological screening of Thymus lotocephalus extracts obtained by supercritical fluid extraction and hydrodistillation
Keywords: ChE، کولین استراز; AAPH, 2,2′-azobis(2-amidinopropane) dihydrochloride; ACh, acetylcholine; AChE, acetylcholinesterase; AD, Alzheimer's disease; ATCI, acetylthiocholine iodide; BChE, butyrylcholinesterase; BTCI, butyrylthiocholine chloride; ChE, cholinesterase; CO2, carbon
Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats
Keywords: ChE، کولین استراز; ANOVA, analysis of variance; ChE, cholinesterase; DM, diabetes mellitus; GSH, reduced glutathione; HFD, high-fat diet; HFE, high-fat emulsion; MDA, malondialdehyde; NO, nitric oxide; PPAR, peroxisome proliferator-activator receptor; STZ, streptozotocintyp
The carboxylesterase/cholinesterase gene family in invertebrate deuterostomes
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; BChE, butyrylcholinesterase; ChE, cholinesterase; CLAM, cholinesterase-like adhesion molecule; CoE, carboxylesterase; GPI, glycophosphotidylinositolacetylcholinesterase; Branchiostoma; butyrylcholinesterase; carboxylesterase; C
Metabonomics analysis of urine and plasma from rats given long-term and low-dose dimethoate by ultra-performance liquid chromatography–mass spectrometry
Keywords: ChE، کولین استراز; UPLC, ultra performance liquid chromatography; ESI-TOF-MS, electrospray ionization time-of-flight mass spectrometry; NOAEL, no observed adversed effect level; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CHE, cholinesterase; ALB, albumi
In vitro detoxification of cyclosarin in human blood pre-incubated ex vivo with recombinant serum paraoxonases
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; BChE, butyrylcholinesterase; ChE, cholinesterase; rePON1, recombinant mammalian paraoxonase 1; CWNA, chemical warfare nerve agent; GF, cyclosarin; ATC, acetylthiocholine iodide; WB, whole bloodParaoxonase; Cholinesterase; Cyclo
Effects of the organophosphate insecticide azinphos-methyl on the reproduction and cholinesterase activity of Biomphalaria glabrata
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; ChE, cholinesterase; ASCh, acetylthiocholine; DTNB, 5,5′-dithio-2-bis-nitrobenzoateAzinphos-methyl; Freshwater snail; Cholinesterase; Reproduction
Esterases activity in the axolotl Ambystoma mexicanum exposed to chlorpyrifos and its implication to motor activity
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; CPF, chlorpyrifos; MLT, malathion, CbEcarboxylesterase; BChE, butyrylcholinesterase; ChE, cholinesterase; OPP, organophosphate pesticide; HS, Holtfreter's solution; DTNB, 5,5-dithio-2-nitrobenzoate; TSP, total soluble protein;
Evolution of and perspectives on therapeutic approaches to nerve agent poisoning
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; AMPA, 2-amino-3-(5-methyl-3-oxo-1-2-oxazol-4-yl)propanoic acid; BBB, blood brain barrier; BuChE, butyrylcholinesterase; CaE, carboxylesterase; CBDP, 2-(o-cresyl)-4H-1,3,2-benzodioxaphosphoran-2-one; ChE, cholinesterase; CNS, ce
Ladostigil prevents age-related glial activation and spatial memory deficits in rats
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; AC, aged controls; AL, aged plus ladostigil; BuChE, butylcholinesterase; CC, corpus callosum; ChE, cholinesterase; DG, dentate gyrus; Fx, fimbria of the fornix; GFAP, glial fibrillary acidic protein; EC, external capsule; IC, i
Human arylacetamide deacetylase is responsible for deacetylation of rifamycins: Rifampicin, rifabutin, and rifapentine
Keywords: ChE، کولین استراز; AADAC, arylacetamide deacetylase; AdAADAC, a recombinant adenovirus expressing human AADAC; AdGFP, a recombinant adenovirus expressing a green fluorescence protein; BNPP, bis-p-nitrophenylphosphate; CES, carboxylesterase; ChE, cholinesterase; DTNB, 5,5′-d
Investigation of structure-activity relationships in organophosphates-cholinesterase interaction using docking analysis
Keywords: ChE، کولین استراز; ChE, cholinesterase; AChE, acetylcholinesterase; BChE, butyrylcholinesterase; OPI, organophosphorus inhibitorCholinesterase; Active center; Organophosphorus inhibitors; Structure-activity relationships; Mammals; Insects
Aging mechanism of butyrylcholinesterase inhibited by an N-methyl analogue of tabun: Implications of the trigonal–bipyramidal transition state rearrangement for the phosphylation or reactivation of cholinesterases
Keywords: ChE، کولین استراز; huBChE, human butyrylcholinesterase; huAChE, human acetylcholinesterase; ChE, cholinesterase; TA4, N-methyl-ethylphosphoramidofluoridate; OPs, organophosphorous compoundsAcetylcholinesterase; Butyrylcholinesterase; Transition state; Nerve agents; Aging; R
Structural approach to the aging of phosphylated cholinesterases
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; BChE, butyrylcholinesterase; ChE, cholinesterase; DFP, diisopropylfluorophosphate; MALDI-TOF, matrix-assisted laser desorption/ionization-time-of-flight; OP, organophosphorus compound; PAS, peripheral anionic site; 2-PAM, prali
Risk assessment induced by knapsack or conventional motor sprayer on pesticides applicators and farm workers in cotton season
Keywords: ChE، کولین استراز; OS, oxidative stress; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ChE, cholinesterase; AChE, acetylcholinesterase; GSH, reduced glutathione; GST, glutathione S-transferase; MDA, malondialdehyde; ROS, reactive oxygen species; GSH-Px, gl
Pro-2-PAM therapy for central and peripheral cholinesterases
Keywords: ChE، کولین استراز; 2-PAM, 2-pralidoxime; ACh, acetylcholine; AChE, acetylcholinesterase; AI, auto-injector; BBB, blood brain barrier; CA1, Cornu Ammonis 1; CA2, Cornu Ammonis 2; ChE, cholinesterase; CNS, central nervous system; DFP, diisopropylfluorophosphate; EDTA, ethylen
Inhibition of cholinesterases and carboxylesterases of two invertebrate species, Biomphalaria glabrata and Lumbriculus variegatus, by the carbamate pesticide carbaryl
Keywords: ChE، کولین استراز; ChE, cholinesterase; AChE, acetylcholinesterase; CES, carboxylesterase; BChE, butyrylcholinesterase; DTNB, 5,5′-dithio-2-bis-nitrobenzoate; OP, organophosphorousCholinesterases; Carbaryl; Carboxylesterases; Biomphalaria glabrata; Lumbriculus variegatus
Effect of in vivo nicotine exposure on chlorpyrifos pharmacokinetics and pharmacodynamics in rats
Keywords: ChE، کولین استراز; OP, organophosphorus; CPF, chlorpyrifos; CPF-oxon, chlorpyrifos-oxon; TCPy, 3,5,6-trichloro-2-pyridinol; AChE, acetylcholinesterase; ChE, cholinesterase; CYP450, cytochrome P450; AUC, area-under-the-curve; PON-1, paroxonase-1; sc, subcutaneous; PBPK/PD, p
A snack enriched with oral branched-chain amino acids prevents a fall in albumin in patients with liver cirrhosis undergoing chemoembolization for hepatocellular carcinoma
Keywords: ChE، کولین استراز; ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BCAA, branched-chain amino acid; BMI, body mass index; BTR, BCAA/tyrosine ratio; ChE, cholinesterase; FPG, fasting blood glucose; HCC, hepatocellular
A model for probabilistic health impact assessment of exposure to food chemicals
Keywords: ChE، کولین استراز; ADI, acceptable daily intake; BMD, benchmark dose; BMDL, benchmark dose lower bound; CED, critical effect dose; ChE, cholinesterase; DALY, disability adjusted life years; Df, degrees of freedom; DW, disability weight; GM, geometric mean; GSD, geometric st
Intrahippocampal cholinesterase inhibition induces epileptogenesis in mice without evidence of neurodegenerative events
Keywords: ChE، کولین استراز; epilepsy; acetylcholine; astrogliosis; Fos; fear conditioning; mouseACh, acetylcholine; AMN, atropine methyl nitrate; ANOVA, analysis of variance; AUC, area under the curve; BSA, bovine serum albumin; ChE, cholinesterase; CNS, central nervous system; CS,
Natural feed additive of Macleaya cordata: Safety assessment in rats a 90-day feeding experiment
Keywords: ChE، کولین استراز; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CYP, cytochrome P450; CH, chelerythrine; CHE, cholinesterase; DHCH, dihydrochelerythrine; DHSG, dihydrosanguinarine; GMT, gamma-glutamyl transpeptidase; GPX, glutat
The toxicity and pharmacokinetics of dihydrosanguinarine in rat: A pilot study
Keywords: ChE، کولین استراز; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AOPP, advanced oxidation protein products; AST, aspartate aminotransferase; AUC, area under the plasma concentration–time curve; CYP, cytochrome P450; CHE, cholinesterase; DHSG, dihydrosanguinarine
A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; BuChE, butyrylcholinesterase; CaE, carboxylesterase; ChE, cholinesterase; DFP, diisopropylfluorophosphate; DFPase, diisopropylfluorophosphate hydrolase; OP, organophosphorus compound; OPAH, organophosphorus acid anhydride hydro
Metabonomic study on the toxicity of Hei-Shun-Pian, the processed lateral root of Aconitum carmichaelii Debx. (Ranunculaceae)
Keywords: ChE، کولین استراز; 1D, one-dimensional; 2-OG, 2-oxoglutarate; CHE, cholinesterase; CPMG, Carr–Purcell–Meiboom–Gill; Crn, creatinine; DMA, dimethylamine; D2O, deuterium oxide; FID, free induction decay; FT, Fourier transform; Ile, isoleucine; LED, longitudinal eddy-delay; NA
Is plasma β-glucuronidase a novel human biomarker for monitoring anticholinesterase pesticides exposure? A Malaysian experience
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; ChE, cholinesterase; BG, β-glucuronidase; OP, organophosphates; EPN, O-ethyl O-p-nitrophenylphenylphosphonothioate; MADA, Muda Agricultural Development AuthorityAnticholinesterase; β-Glucuronidase; Cholinesterase; Organophospha
Effects of statins on α7 nicotinic receptor, cholinesterase and α-form of secreted amyloid precursor peptide in SH-SY5Y cells
Keywords: ChE، کولین استراز; AD, Alzheimer's disease; ACh, acetylcholine; AChE, acetylcholinesterase; Aβ, β-amyloid peptide; APP, β-amyloid precursor peptide; BuChE, butyrylcholinesterase; ChE, cholinesterase; αAPPs, α-form of secreted APP; nAChR, nicotinic acetylcholine receptorStat
Tabernaemontana divaricata extract inhibits neuronal acetylcholinesterase activity in rats
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; ChE, cholinesterase; TDE, Tabernaemontana divaricata extractAcetylcholinesterase inhibitor; Cerebral cortex; Fos
The effect of trichlorfon and methylazoxymethanol on the development of guinea pig cerebellum
Keywords: ChE، کولین استراز; ChAT, choline acetyltransferase; ChE, cholinesterase; GAD, glutamate decarboxylaseBrain development; Guinea pig; Methylazoxymethanol; Teratogen; Trichlorfon
Human paraoxonase: A promising approach for pre-treatment and therapy of organophosphorus poisoning
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; BChE, butyrylcholinesterase; CaE, carboxylesterase; ChE, cholinesterase; DFP, diisopropylfluophosphate; HDL, high density lipoprotein; HPBP, human phosphate binding protein; Hu, human; MRT, mean residence time; OP, organophosph
Cholinesterase inhibition and alterations of hepatic metabolism by oral acute and repeated chlorpyrifos administration to mice
Keywords: ChE، کولین استراز; AChE, acetylcholinesterase; AcThCh, acetylthiocholine; CE, carboxylesterase; ChE, cholinesterase; CPF, chlorpyrifos; CPFO, chlorpyrifos-oxon; CYPs, cytochrome P450 isoforms; DTNB, dithiobisnitrobenzoic acid; G6P, glucose-6-phosphate; G6PDH, glucose-6-phos