Development and evaluation of multifunctional agents for potential treatment of Alzheimer’s disease: Application to a pyrimidine-2,4-diamine template
Keywords: AD, Alzheimer’s disease; ChEIs, cholinesterase inhibitors; hAChE, human acetylcholinesterase; hBuChE, human butyrylcholinesterase; eqBuChE, equinebutyrylcholinesterase; SAR, structure–activity relationship; Aβ, amyloid-β; DTNB, 5,5′-dithiobis(2-nitrobenzo