Growth suppression by ursodeoxycholic acid involves caveolin-1 enhanced degradation of EGFR
Keywords: پیشگیری شیمیایی; Bile acid; Colon cancer; Chemoprevention; c-Cbl; Endocytosis
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5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder
Keywords: پیشگیری شیمیایی; Dithiolethione; Phase 2 enzyme; Nrf2; Chemoprevention; Bladder cancer
Induction of cell cycle arrest in human MCF-7 breast cancer cells by cis-stilbene derivatives related to VIOXX®
Keywords: پیشگیری شیمیایی; Breast cancer; Chemoprevention; Cell cycle; Stilbene derivatives; Structure activity relationship;
Influence of dietary resveratrol on early and late molecular markers of 1,2-dimethylhydrazine–induced colon carcinogenesis
Keywords: پیشگیری شیمیایی; Apoptosis; Cell proliferation; Chemoprevention; 1,2-Dimethylhydrazine; Resveratrol
Nitric oxide-donating aspirin inhibits the growth of pancreatic cancer cells through redox-dependent signaling
Keywords: پیشگیری شیمیایی; NO-NSAIDs; NO-aspirin; Pancreatic cancer; Chemoprevention; Cell signaling; ROS
Development of a rat model by 3,4-benzopyrene intra-pulmonary injection and evaluation of the effect of green tea drinking on p53 and bcl-2 expression in lung carcinoma
Keywords: پیشگیری شیمیایی; Lung neoplasm; Animal model; Rat; Green tea; Chemoprevention; p53 gene; bcl-2 gene
Sulindac Prevents Carcinogen-Induced Intrahepatic Cholangiocarcinoma Formation In Vivo
Keywords: پیشگیری شیمیایی; cholangiocarcinoma; cyclooxygenase; nuclear factor κ-B; sulindac; chemoprevention
Differential effects of cholesterol and phytosterols on cell proliferation, apoptosis and expression of a prostate specific gene in prostate cancer cell lines
Keywords: پیشگیری شیمیایی; Prostate cancer; Caveolin-1; Sterols; Cholesterol; Phytosterols; PCGEM1; Apoptosis; Proto-oncogene; Biomarkers; Chemoprevention
Rheological, sensorial, and chemopreventive properties of milk fermented with exopolysaccharide-producing lactic cultures1
Keywords: پیشگیری شیمیایی; exopolysaccharide; fermented milk; rheology; chemoprevention;
In vitro assessment of P450 induction potential of novel chemopreventive agents SR13668, 9-cis-UAB30, and pentamethychromanol in primary cultures of human hepatocytes
Keywords: پیشگیری شیمیایی; Chemoprevention; SR13668; 9-cis-UAB30; Pentamethylchromanol; Human hepatocytes; CYP1A2; CYP2B6; CYP3A4
Predictors of the use of complementary and alternative medicine (CAM) by women at high risk for breast cancer
Keywords: پیشگیری شیمیایی; Complementary medicine; Alternative medicine; CAM; Familial; BRCA1; BRCA2; Breast cancer; Ovarian cancer; Chemoprevention; Tamoxifen
Induction of heat shock response by curcumin in human leukemia cells
Keywords: پیشگیری شیمیایی; Chemoprevention; Curcumin; Heat shock response; Bag-1; Human chronic myelogenous leukemia
Mechanisms of Hyperforin as an anti-angiogenic angioprevention agent
Keywords: پیشگیری شیمیایی; Hyperforin; Angiogenesis; Inflammation; Neutrophils; Monocytes; Endothelial cells; Chemoprevention;
Nonsteroidal Antiinflammatory Drugs and Cyclooxygenase Inhibition in the Gastrointestinal Tract: A Trip From Peptic Ulcer to Colon Cancer
Keywords: پیشگیری شیمیایی; NSAIDs; Cyclooxygenase; Peptic ulcer; Gastrointestinal bleeding; Colon cancer; Chemoprevention; Aspirin;
Inhibitory effects of oligonol on phorbol ester-induced tumor promotion and COX-2 expression in mouse skin: NF-κB and C/EBP as potential targets
Keywords: پیشگیری شیمیایی; Oligonol; Chemoprevention; Mouse skin; Cyclooxygenase-2; MAPK; NF-κB; C/EBP
Modulation of genomic and postgenomic alterations in noncancer diseases and critical periods of life
Keywords: پیشگیری شیمیایی; AP-1; activator protein-1; BAL; bronchoalveolar lavage; 5,6-BF; 5,6-benzoflavone; B(a)P; benzo(a)pyrene; COPD; chronic obstructive pulmonary diseases; CS; cigarette smoke; Cx43; connexin 43; DMBA; 7,12-dimethylbenz(a)anthracene; ÉdA; 1,N-ethenodeoxyadeni
Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1
Keywords: پیشگیری شیمیایی; Tea polyphenols; Chemoprevention; Lung cancer; Apoptosis; Proliferation
Effect of garlic on lipid peroxidation and antioxidation enzymes in DMBA-induced skin carcinoma
Keywords: پیشگیری شیمیایی; Chemoprevention; Garlic; 7,12-Dimethylbenz[a]anthracene; Skin carcinogenesis; Antioxidants; Lipid peroxidation
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis
Keywords: پیشگیری شیمیایی; Resveratrol; Diethylnitrosamine; Phenobarbital; Hepatocarcinogenesis; Chemoprevention; Cell proliferation; Apoptosis; Bax; Bcl-2; Rat; Liver;
Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine
Keywords: پیشگیری شیمیایی; Lactoferrin; Innate immune system; Cytokine; Chemoprevention; Carcinogenesis
Screening and Prevention of Breast Cancer in Primary Care
Keywords: پیشگیری شیمیایی; Breast cancer screening; Breast cancer prevention; Mammography; Digital mammography; Breast magnetic resonance imaging; Chemoprevention; Risk assessment; Guidelines;
Butylated hydroxytoluene chemoprevention of aflatoxicosis – Effects on aflatoxin B1 bioavailability, hepatic DNA adduct formation, and biliary excretion
Keywords: پیشگیری شیمیایی; AFB1, aflatoxin B1; BHT, butylatated hydroxytoluene; H.E., hematoxylin and eosin; AFBO, AFB1-8,9-epoxide; CYP: P450, cytochrome P450BHT; Chemoprevention; Turkeys; Aflatoxin B1; Aflatoxicosis
Establishment of a bioassay model for lung cancer chemoprevention initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice
Keywords: پیشگیری شیمیایی; NNK; Lung cancer; Bioassay model; Chemoprevention; 8-MOP; A/J mouse
CT detected indeterminate pulmonary nodules in a chemoprevention trial of fluticasone
Keywords: پیشگیری شیمیایی; Chemoprevention; Computer tomography; Inhaled corticosteroids; Lung cancer; Pulmonary nodules; Trial
NO-donating NSAIDs and cancer: An overview with a note on whether NO is required for their action
Keywords: پیشگیری شیمیایی; Nitric oxide; Cancer; NO-NSAIDs; NO-aspirin; Chemoprevention
Apoptosis by dietary agents for prevention and treatment of cancer
Keywords: پیشگیری شیمیایی; Apoptosis; Cancer; Chemoprevention; Dietary agents
Computer-assisted image analysis of breast fine needle aspiration in a randomized chemoprevention trial of fenretinide vs. placebo in HRT users
Keywords: پیشگیری شیمیایی; Biomarker; Breast cancer; Chemoprevention; Estrogen replacement therapy; Fenretinide; Karyometry
Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane
Keywords: پیشگیری شیمیایی; Erucin; Sulforaphane; Isothiocyanates; Chemoprevention; Cytochrome P450; Precision-cut slices
Tissue differences in the modulation of rat cytochromes P450 and phase II conjugation systems by dietary doses of phenethyl isothiocyanate
Keywords: پیشگیری شیمیایی; Phenethyl isothiocyanate; Isothiocyanates; Chemoprevention; Cytochromes P450; Quinone reductase
Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG
Keywords: پیشگیری شیمیایی; Nrf2; EGCG; Antioxidant enzymes; Chemoprevention; Cytoprotection; Green tea
Transcriptional profiles of benzo(a)pyrene exposure in normal human mammary epithelial cells in the absence or presence of chlorophyllin
Keywords: پیشگیری شیمیایی; BP; benzo(a)pyrene; CYP; cytochrome P450; NHMEC; normal human mammary epithelial cell; PAH; polycyclic aromatic hydrocarbon; Carcinogens; Chemoprevention; Chlorophyllin; Gene expression; Polycyclic aromatic hydrocarbons;
Neither Antioxidants nor COX-2 Inhibition Protect Against Esophageal Inflammation in an Experimental Model of Severe Reflux
Keywords: پیشگیری شیمیایی; esophagojejunostomy; inflammation; oxidative stress; antioxidants; COX-2 inhibitor; chemoprevention
β-Glucans in promoting health: Prevention against mutation and cancer
Keywords: پیشگیری شیمیایی; β-Glucans; Antimutagenesis; Biological activities; Chemoprevention; Anticarcinogenic
The use of PSA as biomarker in nutritional intervention studies of prostate cancer
Keywords: پیشگیری شیمیایی; Chemoprevention; Prostate cancer; PSA; Xenograft models;
Chemopreventive effects of Furan-2-yl-3-pyridin-2-yl-propenone against 7,12-dimethylbenz[a]anthracene-inducible genotoxicity
Keywords: پیشگیری شیمیایی; 1-Furan-2-yl-3-pyridin-2-yl-propenone; Chemoprevention; 7,12-Dimethylbenz[a]anthracene; CYP; Phase II enzymes
Intestinal tumour chemoprevention with the antioxidant lipoic acid stimulates the growth of breast cancer
Keywords: پیشگیری شیمیایی; Chemoprevention; Antioxidants; Experimental tumour models; Breast cancer; Intestinal tumours
Indole-3-carbinol enhances anti-proliferative, but not anti-invasive effects of oxaliplatin in colorectal cancer cell lines
Keywords: پیشگیری شیمیایی; Colorectal cancer; Oxaliplatin; Chemoprevention; Indole-3-carbinol; E-Cadherin; β-Catenin
Nonsteroidal Anti-Inflammatory Drugs and Statins Have Chemopreventative Effects in Patients With Barrett's Esophagus
Keywords: پیشگیری شیمیایی; Gastroesophageal Reflux Disease; Chemoprevention; Cancer Risk; TumorBE, Barrett's esophagus; CI, confidence interval; COX, cyclooxygenase; EAC, esophageal adenocarcinoma; HGD, high-grade dysplasia; LGD, low-grade dysplasia; NSAIDs, nonsteroidal anti-infla
A potential paradox in prostate adenocarcinoma progression: Oestrogen as the initiating driver
Keywords: پیشگیری شیمیایی; Anti-oestrogen; CYP1B1; Chemoprevention; Growth-promoting; Initiation; 17β-Oestradiol; Prostate adenocarcinoma; Testosterone
Anti-cancer activity of highly purified sulfur in immortalized and malignant human oral keratinocytes
Keywords: پیشگیری شیمیایی; Apoptosis; Cell-cycle arrest; Chemoprevention; Immortalized keratinocytes; Oral cancer; Purified sulfur
Tamoxifen: Catalyst for the change to targeted therapy
Keywords: پیشگیری شیمیایی; Breast cancer; Chemoprevention; Antioestrogen; Tamoxifen; Raloxifene; Selective oestrogen receptor modulator
Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults
Keywords: پیشگیری شیمیایی; Nrf2; Chemoprevention; Adaptive response; Oxidative stress
Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-κB activation and COX-2 expression in human breast epithelial cells
Keywords: پیشگیری شیمیایی; Human breast epithelial cells; Cyclooxygenase-2; NF-κB; Mitogen-activated protein kinase; Chemoprevention; Phorbol ester;
Evaluation of the cancer chemopreventive efficacy of silibinin in genetic mouse models of prostate and intestinal carcinogenesis: Relationship with silibinin levels
Keywords: پیشگیری شیمیایی; Chemoprevention; Preclinical models; Silibinin; IGF
Dietary agents for chemoprevention of prostate cancer
Keywords: پیشگیری شیمیایی; Chemoprevention; Prostate cancer; Dietary agents
Anthocyanins and their role in cancer prevention
Keywords: پیشگیری شیمیایی; Anthocyanins; Chemoprevention; In vitro; In vivo; Mechanisms
Cadmium induced testicular pathophysiology: Prophylactic role of taurine
Keywords: پیشگیری شیمیایی; Cadmium; Oxidative stress; Testicular pathophysiology; Taurine; Antioxidant; Chemoprevention
Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: In vitro evidence querying the NO donor functionality
Keywords: پیشگیری شیمیایی; Chemoprevention; Quinone oxidoreductase; Hybrid drugs; Antioxidant response element; Quinone methide; Nitrates; Inflammation; NO-ASA; NO-NSAID
Mechanisms by which docosahexaenoic acid and related fatty acids reduce colon cancer risk and inflammatory disorders of the intestine
Keywords: پیشگیری شیمیایی; Protein targeting; Trafficking; Fish oil; Chemoprevention; Colon cancer
Tomato oleoresin inhibits DNA damage but not diethylnitrosamine-induced rat hepatocarcinogenesis
Keywords: پیشگیری شیمیایی; Chemoprevention; Diethylnitrosamine; DNA damage; GST-P liver foci; Hepatocarcinogenesis; Tomato oleoresin; Lycopene;