دانلود مقالات ISI درباره Chk1 Inhibitors + ترجمه فارسی

Synthesis and biological evaluation of 2,6-disubstituted-9H-purine, 2,4-disubstitued-thieno[3,2-d]pyrimidine and -7H-pyrrolo[2,3-d]pyrimidine analogues as novel CHK1 inhibitors

Keywords: CHK1 inhibitors; 9H-purine; Potentiating effect; Anti-proliferative effects;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Design of granulatimide and isogranulatimide analogues as potential Chk1 inhibitors: Study of amino-platforms for their synthesis

Keywords: Marine alkaloid; Isogranulatimide; Granulatimide; Chk1 inhibitors

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Pyridyl aminothiazoles as potent inhibitors of Chk1 with slow dissociation rates

Keywords: Checkpoint kinase; Chk1 inhibitors; DNA damage; Cancer therapy; Combination cancer therapy; Molecular dynamics; ATP-competitive kinase inhibitors

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors

Keywords: CHK1 inhibitors; Thienopyridines; Antitutor agent; Kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

A three-step synthesis from rebeccamycin of an efficient checkpoint kinase 1 inhibitor

Keywords: Rebeccamycin; Staurosporine; Antitumor agents; Indolocarbazoles; Chk1 inhibitors

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone

Keywords: Pyrrolo[3,4-a]carbazole-1,3-diones; 2-Amino-pyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone; Antitumor agents; Chk1 inhibitors

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles

Keywords: Granulatimide; Pyrrolo[3,4-c]carbazoles; Antitumor agents; Chk1 inhibitors;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors

Keywords: 5-Azaindole; 5-Azaindolocarbazole; Chk1 inhibitors; Cytoxicity

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2008 سفارش ترجمه

Discovery of 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors

Keywords: Antitumor agent; Chk1 inhibitors; Checkpoint kinase 1; Pyrazole; Structure–activity relationship; DNA damage; Combination therapy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis and biological activities of isogranulatimide analogues

Keywords: Isogranulatimide; Chk1 inhibitors; Pyrrolo[3,4-c]carbazole; Antitumor drugs

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of indolylpyrazolones and indolylpyridazinedione

Keywords: Indolylpyrazolones; Indolyl-pyridazin-3,6-dione; Antitumor agents; Chk1 inhibitors

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of dipyrrolo[3,4-a:3,4-c]carbazole-triones

Keywords: Granulatimide; Dipyrrolo[3,4-a:3,4-c]carbazole-1,4,6-trione; Dipyrrolo[3,4-a:3,4-c]carbazole-3,4,6-trione; Antitumor agents; Chk1 inhibitors;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Synthesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, substituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions

Keywords: Isogranulatimide; Antitumor agents; Dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraone; Chk1 inhibitors

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Synthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring

Keywords: Rebeccamycin; 7-Azaindole; Antitumor compounds; Chk1 inhibitors; DNA binding agents; Topoisomerase I inhibitors

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه