The human ATR-mediated DNA damage checkpoint in a reconstituted system
Keywords: Chk1 kinase; Topoisomerase IIβ-binding protein (TopBP1); Phosphoinositol 3-kinase related kinase (PIKK); Protein-serine-threonine kinases; Phosphorylation; Protein purification; Preparation of damaged DNA; Benzo[a]pyrene diol epoxide (BPDE); N-acetoxy-2-a