Keywords: کلرومتیاازول; POM; pomegranate; ALD; alcoholic liver disease; TJ; tight junction; AJ; adherent junction; CYP2E1; ethanol-inducible cytochrome P450-2E1; iNOS; inducible nitric oxide synthase; nitroxidative stress; oxidative and nitrative stress; KI mice; knock-in mice;