
Hepatitis B virus basal core promoter mutations show lower replication fitness associated with cccDNA acetylation status
Keywords: BCP; basal core promoter; CHB; chronic HBV; cccDNA; covalently closed circular DNA; DNMT; DNA methyltransferases; DS DNA; double stranded DNA; HATs; histone acetyltransferases; HDAC1; class 1 histone deacetylase; OC DNA; open circular DNA; ORFs; open read