New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data
Keywords: AFE, average fold error; CLh, hepatic clearance; CLint, intrinsic clearance; CLint,h, intrinsic hepatic clearance; CLint,met, intrinsic metabolic clearance; CLint,sec, intrinsic secretory clearance; CLren, renal clearance; CLtot, total clearance; CYP, cyt