Keywords: QTc interval; proarrhythmia; pharmacokinetic/pharmacodynamics models; drug interactions; clinical trial simulations; terfenadine;
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Quality by Design (QbD); bioavailability; biopharmaceutics classification system (BCS); clinical trial simulations; controlled delivery; in silico modeling; in vitro models; in vitro/in vivo correlations (IVIVC); oral drug delivery; pharmacokinetics; phar
Quantitative Analysis of Complex Drug-Drug Interactions Between Repaglinide and Cyclosporin A/Gemfibrozil Using Physiologically Based Pharmacokinetic Models With In Vitro Transporter/Enzyme Inhibition Data
Keywords: clinical trial simulations; drug interactions; pharmacokinetics; physiologically based pharmacokinetic modeling; organic anion-transporting polypeptide transporters; CYP enzymes; AUC; area under the blood concentration-time curve; AUCR; area under the b
Optimizing Clinical Drug Product Performance: Applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid
Keywords: quality by design (QbD); bioavailability; Biopharmaceutics Classification System (BCS); clinical trial simulations; drug delivery; in silico modeling; in vitro models; in vitro and in vivo correlations/relationships (IVIVC/R); Biopharmaceutics Risk Assess
Use of a Physiologically Based Pharmacokinetic Model for Quantitative Prediction of Drug–Drug Interactions via CYP3A4 and Estimation of the Intestinal Availability of CYP3A4 Substrates
Keywords: clinical trial simulations; cytochrome P450; drug interactions; intestinal metabolism; pharmacokinetics; physiologically based pharmacokinetic modeling
Featured ArticleEffect of APOE genotype status on targeted clinical trials outcomes and efficiency in dementia and mild cognitive impairment resulting from Alzheimer's disease
Keywords: Alzheimer disease; Mild cognitive impairment; Apolipoprotein E ε4; Clinical trials; Clinical trial simulations; Biomarkers; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's Disease Cooperative Study; Alzheimer's Disease Assessment Scale;