Keywords: C max، غلظت پلاسما در پلاسما; AUC, area under the curve of plasma concentration vs time; ACEI, angiotensin converting enzyme inhibitor(s); ARB, angiotensin II receptor blocker(s); BNP, B-type natriuretic peptide; CHF, congestive heart failure; Cmax, peak plasma concentration; EGFR, ep
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Keywords: C max، غلظت پلاسما در پلاسما; DOX, doxorubicin; AUC, total area under the plasma concentration–time curve from time zero to time infinity; Cmax, peak plasma concentration; Tmax, time to reach a Cmax; Frel, extent of relative oral bioavailabilityColloidal nanosystem; Medium chain glyce
Keywords: C max، غلظت پلاسما در پلاسما; AUC, area under the curve; CL, plasma clearance; Cmax, peak plasma concentration; CYP, cytochrome P450; FDA, Food and Drug Administration; FEMA, Flavour and Extract Manufacturers Association of the United States; GLP, Good Laboratory Practices; GMP, good
Stereoselective pharmacokinetic and metabolism studies of 20(S)- and 20(R)-ginsenoside Rg3 epimers in rat plasma by liquid chromatography-electrospray ionization mass spectrometry
Keywords: C max، غلظت پلاسما در پلاسما; AUC, area under the curve; Cmax, peak plasma concentration; ig, intra-gastric; IS, internal standard; iv, intravenous; LC–MS/MS, liquid chromatography coupled with tandem mass spectrometry; LLOQ, lower limit of quantitation; MRM, multiple reaction monitor
Pharmacokinetic study of salvianolic acid D after oral and intravenous administration in rats
Keywords: C max، غلظت پلاسما در پلاسما; AUC, the area under curve; CI, confidence interval; CL, clearance; Cmax, peak plasma concentration; ECE-1, endothelin converting enzyme 1; ESI, electrospray ionization; IS, internal standard; LLOQ, lower limit of quantification; QC, quality control; R.E.,
Determination of cefadroxil in rat plasma and urine using LC–MS/MS and its application to pharmacokinetic and urinary excretion studies
Keywords: C max، غلظت پلاسما در پلاسما; AUC, area under the plasma concentration curve; AUC∞, total area under the plasma concentration–time curve from time zero to infinity; AUMC∞, area under the first moment–time curve from time zero to infinity; Cmax, peak plasma concentration; ESI, electro-
Amorphous solid dispersion of berberine with absorption enhancer demonstrates a remarkable hypoglycemic effect via improving its bioavailability
Keywords: C max، غلظت پلاسما در پلاسما; AUC0 ⟶ t, t = 24 h, area under the plasma concentration versus time curve from zero to last sampling time point; Cmax, peak plasma concentration; CL, plasma clearance; dhBer, dihydroberberine; DM, Type 2 Diabetes mellitus; DSC, Differential Scanning Calor
Carcinogenicity in rats of the SGLT2 inhibitor canagliflozin
Keywords: C max، غلظت پلاسما در پلاسما; 45Ca, calcium 45; 45CaCl2, calcium chloride labeled with calcium 45; ANOVA, analysis of variance; AUC, area under the curve; AV, amphophilic-vacuolar; Cmax, peak plasma concentration; CPN, chronic progressive nephropathy; ELISA, enzyme-linked immunosorben
Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms (CYP2C19, ABCB1, PON1), Noncompliance, Diet, Smoking, Co-Medications (Including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet F
Keywords: C max، غلظت پلاسما در پلاسما; drugs; pharmacokinetics; platelets; receptors; risk factorsADP, adenosine phosphate; AUCt, area under the time-concentration curve; BMI, body mass index; ClopidogrelAM, clopidogrel active metabolite; Cmax, peak plasma concentration; CVs, coefficients of v
Hypothalamic-Pituitary-Adrenal Axis Effects of Mometasone Furoate/Formoterol Fumarate vs Fluticasone Propionate/Salmeterol Administered Through Metered-Dose Inhaler
Keywords: C max، غلظت پلاسما در پلاسما; ANOVA, analysis of variance; AUC, area under the plasma concentration-time curve; AUCτ, area under the plasma concentration-time curve 0 to 12 h postdose; Cmax, peak plasma concentration; Ctrough, plasma cortisol trough level; DPI, dry powder inhaler; F,
Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets
Keywords: C max، غلظت پلاسما در پلاسما; AUC, area under the plasma concentration–time curve; Cmax, peak plasma concentration; DHR, dihydroresveratrol; GE, grape extract; MRM, multiple reaction monitoring; MRT, mean residence time; PIS, product ion scan; RW, red wine; tmax, time of peak plasma c
Differential Efficacy of Protease Inhibitors Against HCV Genotypes 2a, 3a, 5a, and 6a NS3/4A Protease Recombinant Viruses
Keywords: C max، غلظت پلاسما در پلاسما; VX-950; SCH503034; TMC435350; ITMN-191; Interferonaa, amino acid; CI, confidence interval; Cmax, peak plasma concentration; EC50, median effective concentration; FFU, focus forming unit(s); IFN, interferon; NS3P, NS3 Protease domain; NS3H, NS3 helicase do
Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic
Keywords: C max، غلظت پلاسما در پلاسما; GGT, γ-glutamyl transpeptidase; GSH, Glutathione reduced; GSSG, Oxidized glutathione; GR, Glutathione reductase; Cmax, Peak plasma concentration; C0, Baseline plasma concentration; Tmax, Time to reach peak plasma concentration; AUC0–30 min, Total area und
Pulmonary delivery of cisplatin–hyaluronan conjugates via endotracheal instillation for the treatment of lung cancer
Keywords: C max، غلظت پلاسما در پلاسما; AUC, area-under-the-curve; CDDP, cis-diamminedichloroplatinum (II), cisplatin; HA–Pt, hyaluronan–CDDP conjugate; Cmax, peak plasma concentration; l.i., lung instillationCisplatin; Hyaluronan; Pharmacokinetics; Pulmonary delivery; Lung chemotherapeutics
Pramlintide Lowered Glucose Excursions and Was Well-Tolerated in Adolescents with Type 1 Diabetes: Results from a Randomized, Single-Blind, Placebo-Controlled, Crossover Study
Keywords: C max، غلظت پلاسما در پلاسما; AUC, Area under the concentration curve; Cmax, Peak plasma concentration; CI, Confidence interval; CV, Coefficient of variation; CL/F, Apparent clearance; DCCT, Diabetes Control and Complications Trial; GLP-1, Glucagon-like peptide-1; LS, Least squares; S
Pharmacokinetics of olanzapine in Chinese male schizophrenic patients with various smoking behaviors
Keywords: C max، غلظت پلاسما در پلاسما; CYP, cytochrome P450; k, elimination rate constant; t1/2, half-life; Tmax, time to reach the peak plasma concentration; Cmax, peak plasma concentration; AUC0→120, area under the plasma concentration–time curve from time of dosing to the last sampling time
An overview of chromatographic methods coupled with mass spectrometric detection for determination of angiotensin-converting enzyme inhibitors in biological material
Keywords: C max، غلظت پلاسما در پلاسما; ACE, angiotensin-converting enzyme; ACEI, angiotensin-converting enzyme inhibitor; ACN, acetonitrile; ATC, anatomical therapeutic chemical; C18, octadecyl; C8, octyl; CI, chemical ionization; Cmax, peak plasma concentration; CN, cyanopropyl; EA, ethyl ace
Dose-Independent Pharmacokinetics of Metformin in Rats: Hepatic and Gastrointestinal First-Pass Effects
Keywords: C max، غلظت پلاسما در پلاسما; metformin; pharmacokinetics; gastrointestinal and hepatic first-pass effects; rats; AUC, total area under the plasma concentration-time curve from time zero to time infinity; CL, time-averaged total body clearance; CLR, time-averaged renal clearance; CL