Keywords: فروپاشی دمای; Freeze-drying; Cycle development; Bulking agent; Mannitol; Sucrose; Glycerol; Protein stability; Glass transition; Collapse; Crystallization; A; annealing step; aFD; after freeze-drying; API; active pharmaceutical ingredient; AUC; area under the curve; bF
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Keywords: فروپاشی دمای; Lyophilisation; Modelling; Mass transfer; Nucleation; Collapse temperature; Silver iodide;
Keywords: فروپاشی دمای; AFM; atomic force microscopy; BSA; bovine serum albumin; CD; circular dichroism; Cgâ²; maximal concentration of the cryoconcentrated solution; DSC; differential scanning calorimetry; ESCA; electron spectroscopy for chemical analysis; ESEM; environmental
Development of a non-toxic and non-denaturing formulation process for encapsulation of SDF-1α into PLGA/PEG-PLGA nanoparticles to achieve sustained release
Keywords: فروپاشی دمای; AFM; atomic force microscopy; BSA; bovine serum albumin; CXCR4; C-X-C chemokine receptor type 4; DL; drug loading; DMEM; Dulbecco's Modified Eagle's Medium; DMI; isosorbide dimethyl ether/dimethyl isosorbide; DMSO; dimethyl sulfoxide; EE; encapsulatio
Lyophilized Drug Product Cake Appearance: What Is Acceptable?
Keywords: فروپاشی دمای; lyophilization; processing; freeze drying; protein formulation; drying; formulation; glass transition; stability; amorphous; CQA; critical quality attribute; Tc; collapse temperature; Tgâ²; glass transition temperature of the maximally freeze-concentrate
Physico-chemical characterisation of cationic DOTAP liposomes as drug delivery system for a hydrophilic decapeptide before and after freeze-drying
Keywords: فروپاشی دمای; DOTAP; Liposome; Lyophilisation; Hydrophilic peptide; Freeze-drying microscope; Collapse temperature
Freeze drying of nanosuspensions, 2: the role of the critical formulation temperature on stability of drug nanosuspensions and its practical implication on process design
Keywords: فروپاشی دمای; freeze drying; lyophilization; nanosuspensions; nanotechnology; vitrification; glass transition; collapse temperature; compounding; stabilization;
Freeze-Dry Microscopy of Protein/Sugar Mixtures: Drying Behavior, Interpretation of Collapse Temperatures and a Comparison to Corresponding Glass Transition Data
Keywords: فروپاشی دمای; freeze-dry microscopy; proteins; collapse temperature; glass transition temperature
Rapid determination of dry layer mass transfer resistance for various pharmaceutical formulations during primary drying using product temperature profiles
Keywords: فروپاشی دمای; Collapse temperature; Dry layer product resistance parameters; FORTRAN; Lactose dehydrogenase (LDH); 5% Mannitol; Mass transfer resistance; Micro-collapse; Newton–Ralphson iteration; Powell's optimization algorithm; Primary drying; Primary drying subrouti
Physical characterisation of formulations for the development of two stable freeze-dried proteins during both dried and liquid storage
Keywords: فروپاشی دمای; Protein formulation; Storage stability; Crystalline and amorphous bulking agents; Differential scanning calorimetry; Freeze-drying microscopy; Glass transition temperature; Collapse temperature; Freeze-drying;