The CRF1 receptor antagonist, NBI-35965, abolished the activation of locus coeruleus neurons induced by colorectal distension and intracisternal CRF in rats
Keywords: اختلال کولورکتال; Neurotransmitters, modulators, transporters and receptors; Peptides: physiology; CRD; colorectal distension; CRF; corticotropin-releasing factor; IBS; irritable bowel syndrome; ic; intracisternal; icv; intracerebroventricular; im; intramuscular; iv; intra