
Adsorption mechanism of acids and bases in reversed-phase liquid chromatography in weak buffered mobile phases designed for liquid chromatography/mass spectrometry
Keywords: ناهمگنی ستون; Overloaded band profiles, acids and bases compounds; C18C18 reversed-phase columns; Weak buffer capacity; Nonlinear chromatography; Competitive adsorption isotherms; Column heterogeneity; Silanol activity; Silica; pKapKa of the analyte