Keywords: غربالگری ترکیبی; Colonic Epithelial Cells; Monolayer; Organoids; Compound Screening; ALP; alkaline phosphatase; α-ChgA; anti-chromogranin A; α-Muc2; anti-mucin2; CAG; cytomegalovirus enhancer plus chicken actin promoter; CI; confidence interval; 2-D; two-dimensional; 3-
مقالات ISI غربالگری ترکیبی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: غربالگری ترکیبی; High-throughput; Compound screening; Cardiac safety; Open source; Action potential; Mathematical model;
Keywords: غربالگری ترکیبی; Canine; Mammary gland tumour cell lines; Metastases; Mitochondrial respiratory chain complex inhibitors; Chemotherapy; Compound screening;
Establishment of a novel microscale thermophoresis ligand-binding assay for characterization of SLC solute carriers using oligopeptide transporter PepT1 (SLC15 family) as a model system
Keywords: غربالگری ترکیبی; Microscale thermophoresis (MST); Ligand-binding assay (LBA); Compound screening; Membrane transport; Solute carrier family SLC; Drug discovery;
A flow cytometer-based method to simultaneously assess activity and selectivity of compounds against the intracellular forms of Trypanosoma cruzi
Keywords: غربالگری ترکیبی; Trypanosoma cruzi; Fluorescent parasites; Flow cytometry; Compound screening; Drug efficacy; Cytotoxicity; Selectivity index; Propidium iodide;
Development of a screening method to identify regulators of MICA shedding
Keywords: غربالگری ترکیبی; MICA; Compound screening; Shedding assay; Reporter;
Prediction of Thorough QT study results using action potential simulations based on ion channel screens
Keywords: غربالگری ترکیبی; AP(D); action potential (duration); AZ; AstraZeneca; B&Q2; IonWorks Barracuda and second Quattro screening dataset; GLP; good laboratory practice; GSK; GlaxoSmithKline; IC50; concentration for 50% inhibition; ICaL; long-lasting-type calcium current; IKr;
Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge
Keywords: غربالگری ترکیبی; AP (D); Action Potential (Duration); ECG; electrocardiogram; ECVAM; European Centre for the Validation of Alternative Methods; FLIPR; FLuorescence Imaging Plate Reader; GSK; GlaxoSmithKline; hERG; human-Ether-a-go-go Related Gene; IC50; Concentration for
6-[(1-naphthylmethyl)sulfanyl]-9H-purine induces G2/M phase arrest and apoptosis in human hepatocellular carcinoma HepG2 cells
Keywords: غربالگری ترکیبی; 6-[(1-naphthylmethyl)sulfanyl]-9H-purine; Anti-cancer; Proliferation; Apoptosis; 6-mercaptopurine; Compound screening
Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction
Keywords: غربالگری ترکیبی; Fluorescence polarization; Cancer chemoprevention; Compound screening; Nrf2; Keap1; Free radicals
Screening for inhibitors of the SOD1 gene promoter: Pyrimethamine does not reduce SOD1 levels in cell and animal models
Keywords: غربالگری ترکیبی; Amyotrophic lateral sclerosis; SOD1; Superoxide dismutase; Assay; Compound screening; Pyrimethamine
Discovery of a novel TLR2 signaling inhibitor with anti-viral activity
Keywords: غربالگری ترکیبی; Toll-like receptor (TLR); Lymphocytic choriomeningitis virus (LCMV); Compound screening
The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development
Keywords: غربالگری ترکیبی; HepG2 cells; Compound screening; High-throughput; Luminescence; RAD51C; Cystatin A; p53; Nrf2; Genotoxicity; Clastogenicity; ECVAM genotoxicity list
Evaluation of the Vitotox⢠and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development
Keywords: غربالگری ترکیبی; RadarScreen; Vitotoxâ¢; Compound screening; High-throughput; Luminescence; Genotoxicity; RAD54; Clastogenicity; ECVAM genotoxicity compound list;
Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method
Keywords: غربالگری ترکیبی; Compound screening; High-throughput; In vitro assay; Genotoxicity; Genotoxin; Genetic toxicology; GADD45a; Transcriptional induction; Green fluorescent protein; GreenScreen HC; TK6; Human lymphoblastoid; Interlaboratory; Transferability
Non-invasive fluorescent imaging of gliosis in transgenic mice for profiling developmental neurotoxicity
Keywords: غربالگری ترکیبی; Non-invasive imaging; GFAP; Gliosis; Developmental neurotoxicology; Compound screening
High-specificity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay
Keywords: غربالگری ترکیبی; Compound screening; Profiling; ADMET; High-throughput screening; Genotoxicity; Genotoxin; Genetic toxicology; GADD45a; GADD45 alpha; Transcriptional induction; Green fluorescent protein; In vitro assay; GreenScreen HC; TK6; Lymphoblastoid