دانلود مقالات ISI درباره COMT، catechol-O-methyl transferase + ترجمه فارسی

اثرات متفاوتی از کتامین و استیل ال-کارنیتین بر روی سیستم دوپامین در ماهی قزل آلا

Distinct effects of ketamine and acetyl l-carnitine on the dopamine system in zebrafish

Keywords: COMT، catechol-O-methyl transferase; COMT, catechol-O-methyl transferase; DA, dopamine; DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid; MAO, monoamine oxidase; 3-MT, 3-methoxytyramineKetamine; Zebrafish; Acetyl l-carnitine; Dopamine; Tyrosine hydroxylase; MAO

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Rotigotine: The first new chemical entity for transdermal drug delivery

Keywords: COMT، catechol-O-methyl transferase; ADME, Absorption Distribution Metabolism Excretion; AUC, area under the plasma concentration time curve; BE, bioequivalence; CGI, Clinical Global Improvement; Cmax, maximum plasma concentration; COMT, catechol-O-methyl transferase; EMA, European Medicines

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist

Keywords: COMT، catechol-O-methyl transferase; BSA, bovine serum albumin; CNS, central nervous system; COMT, catechol-O-methyl transferase; EIC, extracted ion current; IS, internal standard; NADPH, nicotinamide adenine dinucleotide phosphate; NMDA, N-methyl-d-aspartate; PAPS, adenosine 3′-phosphate 5′

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Role of aldo–keto reductase family 1 (AKR1) enzymes in human steroid metabolism

Keywords: COMT، catechol-O-methyl transferase; AKR, aldo–keto reductase; AR, androgen receptor; CAR, constitutive androstane receptor; CRPC, castrate resistant prostate cancer; COMT, catechol-O-methyl transferase; CYP, cytochrome P450 superfamily; 3α/β-Diol, 5α-androstane-3α/β,17β-diol; 5α/β-DHT, 5α/β

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Uptake and metabolism of olive oil polyphenols in human breast cancer cells using nano-liquid chromatography coupled to electrospray ionization–time of flight-mass spectrometry

Keywords: COMT، catechol-O-methyl transferase; BPC, base peak chromatogram; COMT, catechol-O-methyl transferase; D-Lig Agl, deacetoxy ligstroside aglycon; DOA, deacetoxy oleuropein aglycon; EIC, extracted ion chromatogram; EVOO, extra virgin olive oil; Lig Agl, ligstroside aglycon; nanoLC–ESI–TOF MS,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Neurotoxin-based models of Parkinson's disease

Keywords: COMT، catechol-O-methyl transferase; Parkinson's disease; animal models; 6-hydroxydopamine; MPTP; rotenone; paraquatASK1, apoptosis signal-regulating kinase 1; Bax, Bcl2-associated X protein; COMT, catechol-O-methyl transferase; DAT, dopamine transporter; JNK, c-jun N-terminal kinases; l-dop

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of estrogen quinone-derived protein adducts and their identification in human serum albumin derived from breast cancer patients and healthy controls

Keywords: COMT، catechol-O-methyl transferase; AhR, arylhydrocarbon receptor; Alb, albumin; COMT, catechol-O-methyl transferase; Cp, cytoplasmic proteins; CYP1A1, cytochrome P450 1A1; CYP1B1, cytochrome P450 1B1; DMSO, dimethyl sulfoxide; E2, 17β-estradiol; E2-2,3-Q, 17β-estradiol-2,3-quinone; E2-3,4-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Genetic influence on the working memory circuitry: Behavior, structure, function and extensions to illness

Keywords: COMT، catechol-O-methyl transferase; WMem, working memory; DRT, delayed response task; DAS, delayed anti-saccade task; WCST, Wisconsin card sort task; DLPFC, dorsolateral prefrontal cortex; BA, Brodmann's area; COMT, catechol-O-methyl transferase; DAT, dopamine transporter; PKU, phenylketonu

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

The environment and susceptibility to schizophrenia

Keywords: COMT، catechol-O-methyl transferase; BMI, body mass index; CB1, cannabinoid receptor 1; CHDS, Child Health and Development Study; CMV, cytomegalovirus; CNS, central nervous system; CNVs, copy number variants; COMT, catechol-O-methyl transferase; CPP, Collaborative Perinatal Project; CRH, cor

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2011 سفارش ترجمه

Genetic polymorphisms in the dopamine-2 receptor (DRD2), dopamine-3 receptor (DRD3), and dopamine transporter (SLC6A3) genes in schizophrenia: Data from an association study

Keywords: COMT، catechol-O-methyl transferase; Dopamine D2 receptor; Dopamine D3 receptor; Dopamine transporter; Genetic association; Schizophreniabp, base pair; CI, confidence interval; df, degrees of freedom; COMT, catechol-O-methyl transferase; DAT, dopamine transporter; DAT1, dopamine transporter

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats

Keywords: COMT، catechol-O-methyl transferase; obesity-prone phenotype; opioid receptors; caudate putamen; dietary fat; dietary sugarAAAD, aromatic l-amino acid decarboxylase; COMT, catechol-o-methyl transferase; CPu, caudate putamen; DAT, dopamine transporter; DIO, diet-induced obesity; D1, dopamine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia

Keywords: COMT، catechol-O-methyl transferase; 2-AG, 2-arachidonoylglycerol; AMPA, alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; Ca, calcium; CB, cannabinoid; COMT, catechol-O-methyl transferase; eCB, endocannabinoid; GABA, gamma-aminobutyric acid; LTD, long-term depression; LTP, long-term p

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Interaction between serotonin transporter promoter and dopamine receptor D4 polymorphisms on decision making

Keywords: COMT، catechol-O-methyl transferase; ANOVA, analysis of variance; BIS-11, Barratt impulsiveness scale; bp, base pair; COMT, catechol-O-methyl transferase; DRD4, dopamine receptor D4; DRD4 2+, DRD4, 2 repeat carrier; DRD4 2−, DRD4, 2 repeat non-carrier; 5-HTTLPR, serotonin transporter linked

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Acute and long-term cardiovascular effects of coffee: Implications for coronary heart disease

Keywords: COMT، catechol-O-methyl transferase; CHD, Coronary heart disease; COMT, Catechol-O-methyl transferase; CRP, C-reactive protein; CYP, Cytochrome P450; HMG-CoA, 3-hydroxy-3-methylglutaryl-coenzyme A; LDL, low density lipoprotine; MTHFR, methylenetetrahydrofolate reductaseBlood pressure; Caffei

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of metabolite profiles of the catechol-O-methyl transferase inhibitor tolcapone in rat urine using LC/MS-based metabonomics analysis

Keywords: COMT، catechol-O-methyl transferase; UPLC/MS, ultra performance liquid chromatography/mass spectrometry; COMT, catechol-O-methyl transferase; PD, Parkinson's disease; PCA, principal component analysis; LTBS, liver toxicity biomarker study; TIC, total ion chromatogramsUPLC/MS; Metabonomics; T

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Impact of serotonin transporter and catechol-O-methyl transferase genes polymorphism on gastrointestinal dysfunction in Swedish and Japanese familial amyloidotic polyneuropathy patients

Keywords: COMT، catechol-O-methyl transferase; FAP, familial amyloidotic polyneuropathy; ATTR, amyloidogenic transthyretin; Val30Met, Valine30Methionine; 5-HTTLPR, serotonin transporter gene-linked polymorphic region; COMT, catechol-O-methyl transferase; IBS, irritable bowel syndrome; PCR, polymerase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Comparison of genistein metabolism in rats and humans using liver microsomes and hepatocytes

Keywords: COMT، catechol-O-methyl transferase; Genistein; Microsomes; Cryopreserved hepatocytes; Cytochrome P450s; In silico approach; MetabolismATP, adenosine triphosphate; CAD, collision-activated dissociation; COMT, catechol-O-methyl transferase; CYP, cytochrome P450; DNA, deoxyribonucleic acid; ER

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Neurochemical pathways involved in the protective effects of nicotine and ethanol in preventing the development of Parkinson's disease: Potential targets for the development of new therapeutic agents

Keywords: COMT، catechol-O-methyl transferase; ACh, acetylcholine; ADH, alcohol dehydrogenase; Bax, pro-apoptotic group 1 member of Bcl-2 family; Bcl-2, B-cell leukemia gene 2; Ca++, calcium; c-Jun, transcription factor c-Jun; COMT, catechol-O-methyl transferase; COX-2, cyclooxygenase (prostaglandin H

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Noradrenaline involvement in basic and higher integrated REM sleep processes

Keywords: COMT، catechol-O-methyl transferase; AMPT, α-methyl-para-tyrosine; CNQX, 6-cyano-7-nitroquinoxaline-2-3-dione; COMT, catechol-O-methyl transferase; DMI, desmethylimipramine; DOPA, dihydroxyphenylalanine; DOPS, d,l-thyreo-3,4-dihydroxyphenylserine; DSP-4, N-(2-chlorethyl)-N-ethyl-2-bromobenzy

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes

Keywords: COMT، catechol-O-methyl transferase; AG, aminoguanidine; BQ, benzoquinone; 4-ClBP, 4-chloro-biphenyl; COMT, catechol-O-methyl transferase; GSH, glutathione; HQ, hydroquinone; PCBs, polychlorinated biphenyls; ROS, reactive oxygen species; SULT, cytosolic sulfotransferase; UGT, uridine diphosp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Differential nicotinic regulation of the nigrostriatal and mesolimbic dopaminergic pathways: Implications for drug development

Keywords: COMT، catechol-O-methyl transferase; Nicotine; Epibatidine; Dopamine; Nigrostriatal pathway; Mesolimbic pathway; Rotational behavior; Locomotor activity; Place preference; Parkinson's disease; Schizophreniaα-Ctx, α-conotoxin; CNS, central nervous system; COMT, catechol-O-methyl transferase;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2007 سفارش ترجمه

Trace amine-associated receptor 1—Family archetype or iconoclast?

Keywords: COMT، catechol-O-methyl transferase; AADC, aromatic amino acid decarboxylase; ADHD, attention deficit hyperactivity disorder; ATCC, American Type Culture Collection; cAMP, adenosine 3′,5′-monophosphate; cDNA, complementary deoxyribonucleic acid; COMT, catechol-O-methyl transferase; CFTR, cys

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2007 سفارش ترجمه