Keywords: COX-2، cyclooxygenase-2; MDA, malondialdeyde; TNF-α, tumor necrosis factor alpha; DA, dopamine; 5-HT, serotonin; NO, nitric oxide; IL-6, interleukin-6; COX-2, cyclooxygenase-2; PGs, prostaglandins; FA, fatty acids; AMPH, amphetamine; RIS, risperidone; CELECO, celecoxib; OMEG-3, o
مقالات ISI COX-2، cyclooxygenase-2 (ترجمه نشده)
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Keywords: COX-2، cyclooxygenase-2; AP-1, activator protein 1; AR, androgen receptor; cAMP, cyclic adenosine monophosphate; p57, Kip2, cyclin-dependent kinase inhibitor 1C; COX-2, cyclooxygenase-2; DC, deisobutyrylciclesonide; Dex, dexamethasone; KA, dissociation constant; ER, oestrogen rec
Keywords: COX-2، cyclooxygenase-2; AMB, ambient; BWE, black walnut extract; CHO, carbohydrate overload; COX-2, cyclooxygenase-2; DAMPs, damage-associated molecular associated molecular patterns; DEV, developmental; HPF, high power field; NF-kβ, nuclear factor kappa B; OF, oligofructose; OG
Keywords: COX-2، cyclooxygenase-2; ACA, Allium cepa agglutinin; ASA, Allium sativum agglutinin; COX-2, cyclooxygenase-2; CP, cyclophosphamide; Hb, hemoglobin; LPS, lipopolysaccharide; LYM, lymphocytes; NO, nitric oxide; PBS, phosphate-buffered saline; PECs, peritoneal exudates cells; SRBC,
Keywords: COX-2، cyclooxygenase-2; Act. D, actinomycin D; BR, bilirubin; BV, biliverdin; CHX, cycloheximide; CO, carbon monoxide; COX-2, cyclooxygenase-2; ERK1/2, extracellular signal regulated protein kinase 1/2; Fe2 +, ferrous iron; HO-1, heme oxygenase-1; IκB, inhibitory κB; IL-6, inte
Keywords: COX-2، cyclooxygenase-2; ACK, ammonium-chloride-potassium; BCS, bovine calf serum; BMDM, bone marrow derived macrophage; CFA, complete Freund’s adjuvant; CIA, collagen-induced arthritis; COX-2, cyclooxygenase-2; DC-STAMP, dendritic cell–specific transmembrane protein; DMARD, dise
Keywords: COX-2، cyclooxygenase-2; Harpagoside (PubChem CID: 5281542); Hyperoside (PubChem CID: 5281643); Hypoxoside (PubChem CID: 6438448; Oleuropein (PubChem CID: 5281544); Polydatin (PubChem CID: 5281718)AO, acridine orange; AP-1, activating protein-1; COX-2, cyclooxygenase-2; CREB, cAM
Keywords: COX-2، cyclooxygenase-2; Adhatoda vasica; Chemokines; Inflammation; Oxidative stress; Rheumatoid arthritis; TLR-2AVE, Adhatoda vasica extract; CAT, Catalase; CFA, Complete Freund's adjuvant; CIA, Collagen induced arthritis; COX-2, Cyclooxygenase-2; CRP, C-reactive protein; DTNB,
Keywords: COX-2، cyclooxygenase-2; Angiogenesis; Polyphenols; Cyclooxygenase-2; Vascular endothelial growth factor; InflammationANOVA, analysis of variance; BME, basement membrane extract; COX-2, cyclooxygenase-2; DMEM, Dulbecco modified Eagle medium; ELISA, enzyme-linked immunosorbant ass
Keywords: COX-2، cyclooxygenase-2; AGP, Andrographolide; APT1, Acyl protein thioesterase 1; COX-2, cyclooxygenase-2; DPI, Dual prenylation inhibitor; ERK, Extracellular signal-regulated kinase; FBDD, Fragment-based drug discovery; FTase, Farnesyltransferase; FTIs, Farnesyltransferase inhib
Keywords: COX-2، cyclooxygenase-2; AD, Alzheimer’s disease; AML, Acute myeloid leukemia; ApoE, Apolipoprotein; ARE/EpRE, Antioxidant/electrophile responsive element; COX-2, Cyclooxygenase-2; cdk5, Cyclin-dependent kinase 5; EAE, Experimental autoimmune encephalomyelitis; ER, Endoplasmic re
Keywords: COX-2، cyclooxygenase-2; APC, adenomatous polyposis coli; BA, bile acids; BSH, bile salt hydrolases; CA, cholic acid; CDCA, chenodeoxycholic acid; COX-2, cyclooxygenase-2; CRC, colorectal cancer; CYP27A1, sterol-27-hydroxylase; CYP7A1, cholesterol 7α-hydroxylase; CYP8B1, sterol 1
Keywords: COX-2، cyclooxygenase-2; BSA, bovine serum albumin; CII, type II collagen; CFA, complete Freund’s adjuvant; COX-2, cyclooxygenase-2; iNOS, inducible nitric oxide synthase; NSAIDs, nonsteroidal anti-inflammatory drugs; PBS, phosphate buffer saline; PFA, paraformaldehyde; PMA, phor
Keywords: COX-2، cyclooxygenase-2; Free fatty acids; Acetaminophen; Liver; Cyclooxygenase; EicosanoidsAPAP, acetaminophen; ELOVL, elongases; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; ALT, alanine aminotransferase; AST, aspartate aminotransferase; DAB, 3,3′-Diaminobenzidine; PBS, ph
Keywords: COX-2، cyclooxygenase-2; ABCA1, ATP-binding cassette transporter A1; ApoA-1, apolipoprotein A-1; ApoE, apolipoprotein E; CNS, central nervous system; COX, cyclooxygenase; COX-2, cyclooxygenase-2; Cyp46a1, cholesterol 24-hydroxylase; Dhcr24, 24-dehydrocholesterol reductase; Dhcr7,
Keywords: COX-2، cyclooxygenase-2; 2OC, two-organ-chip; 3D, three-dimensional; ACTB, β-actin; ASCs, adipose-derived stromal cells; CD31, cluster of differentiation 31 (also PECAM-1); COX-2, cyclooxygenase-2; eNOS, endothelial nitric oxide synthase; GAPDH, glyceraldehyde 3-phosphate dehydro
Keywords: COX-2، cyclooxygenase-2; ADHD, attention deficit hyperactivity disorder; COX-2, cyclooxygenase-2; ELA, early life adversity; HPA, hypothalamic-pituitary axis; IFN, interferon; IL, interleukin; PFC, prefrontal cortex; PTSD, post-traumatic stress disorder; SHP, stress hyporesponsiv
Keywords: COX-2، cyclooxygenase-2; ANOVA, analysis of variance; BR, HER2-transfected MDA-MB-231BR; BMBC, brain metastatic breast cancer; COX-2, cyclooxygenase-2; DME/F-12, Dulbecco’s modified Eagle’s/F-12 medium; ERK, extracellular signal-regulated kinase; EGFR, human epidermal growth fact
Keywords: COX-2، cyclooxygenase-2; Kerosene; Exposure; Toxicity; Organ/system; Mechanism; HealthAhR, aryl hydrocarbon receptor; ALP, alkaline phosphatase; BAPH, benzo[a]pyrene hydroxylase; CNS, central nervous system; COX-2, cyclooxygenase-2; EGME, ethylene glycol monomethyl ether; HAP, ho
Keywords: COX-2، cyclooxygenase-2; ALK1, activin receptor-like kinase 1; ANG, angiotensinogen; AT1, angiotensin receptor type 1; AT1-AA, angiotensin receptor type 1-autoantibody; BMI, body mass index; BP, blood pressure; CI, confidence interval; COX-2, cyclooxygenase-2; CRP, C-reactive pro
Keywords: COX-2، cyclooxygenase-2; CNS, central nervous system; PPHN, persistent pulmonary hypertension in the newborn; PDA, patent ductus arteriosus; Glut-1, glucose transporter-1; HIF-1, hypoxic inducible factor-1; VEGF, vascular endothelial growth factor; COX-2, cyclooxygenase-2; Ang-1,
Keywords: COX-2، cyclooxygenase-2; AG, aminoguanidine hemisulfate salt; CBMN, cytokinesis-B blocked micronucleus; CHO, Chinese hamster ovary; CO, carbon monoxide; CORM, CO releasing molecule; COX-2, cyclooxygenase-2; DAF-FM, 4-amini-5-methylamino-2′,7′-difluorofluorescein diacetate; DCF, 2
Keywords: COX-2، cyclooxygenase-2; ASAP, Anticancer Screening Apoptosis Program; CDCl3, deuterated chloroform; DMEM/F-12, Dulbecco’s Modified Eagle Medium: Nutrient Mixture F-12; DMSO, dimethyl sulfoxide; eV, electron volt; FBS, fetal bovine serum; COX-2, cyclooxygenase-2; IC50, half maxim
Keywords: COX-2، cyclooxygenase-2; COX-2, cyclooxygenase-2; PGs, prostaglandins; MMPs, matrix metalloproteinases; ECM, extracellular matrix; PCNA, proliferating cell nuclear antigen; DMSO, dimethylsulfoxide; DAPI, 4′,6-diamidine-2′-phenylindole dihydrochloride; MTT, 3-(4,5-dimethylthiazol-
Keywords: COX-2، cyclooxygenase-2; AKT, serine/threonine protein kinase (v-akt murine thimoma viral oncogene homolog1); apoB48, apolipoprotein B48; CD, Crohns disease; COX-2, cyclooxygenase-2; Cys, cysteine; DSS, dextran sodium sulfate; ERK, extracellular signal-regulated kinase; GRP, grap
Keywords: COX-2، cyclooxygenase-2; AL, ad libitum; ANOVA, analysis of variance; CBG, corticosteroid binding globulin; CORT, corticosterone; COX-2, cyclooxygenase-2; CR, calorie restriction; CRH, corticotropin-releasing hormone; IL-6, interleukin-6; ELISA, enzyme-linked immunosorbent assays
Keywords: COX-2، cyclooxygenase-2; ACh, acetylcholine; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; DHE, dihydroethidium; DMPO, 5,5-dimethyl-l-pyrroline-N-oxide; DTPA, diethylenetriaminepentaacetic acid; EDCFs, endothelium-derived contracting factors; EDR, endothelium-dependent relaxa
Keywords: COX-2، cyclooxygenase-2; 6-OHDA, 6-hydroxydopamine; BCIP, 5-bromo-4-chloro-3-indolyl phosphate; COX-2, cyclooxygenase-2; DTNB, 5,5-Dithiobis 2-Nitrobenzoic acid; ETC, electron transport chain; GFAP, glial fibrillary acidic protein; HSP, heat shock proteins; HSF-1, heat shock fact
Keywords: COX-2، cyclooxygenase-2; AD, Alzheimer׳s disease; CA, Centella asiatica; CCA, common carotid artery; c-IAP, cellular inhibitor of apoptosis; Cox-2, cyclooxygenase-2; CPA, cyclophosphamide; ECA, external carotid artery; ELISA, enzyme-linked immunosorbent assay; GSH, glutathione; H
Keywords: COX-2، cyclooxygenase-2; BPH, benign prostatic hyperplasia; BRMS1, breast cancer metastasis suppressor 1; COX-2, cyclooxygenase-2; CRC, colorectal cancer; EMT, epithelial-to-mesenchymal transition; GVHD, graft-versus-host disease; HCC, hepatocellular carcinoma; MMP, matrix metall
Keywords: COX-2، cyclooxygenase-2; Head and neck squamous cell carcinoma; Radiotherapy; Molecular targeted therapy; Preclinical models; Clinical trials; Epidermal growth factor receptor5-FU, 5-fluorouracil; COX-2, cyclooxygenase-2; DNA-PKcs, DNA-dependent protein kinase, catalytic subunit;
Keywords: COX-2، cyclooxygenase-2; ACE, angiotensin-converting enzyme; ACTH, adrenocorticotrophic hormone; APO, apolipoprotein; ATP4B, H+/K+ ATPase; BDNF, brain-derived neurotrophic factor; CAARMS, comprehensive assessment of at-risk mental states; COX-2, cyclooxygenase-2; CRF, corticotrop
Keywords: COX-2، cyclooxygenase-2; Puerarin; Nickel; Liver; Inflammation; TLR4; CREBALT, alanine aminotransferase; AST, aspartate aminotransferase; CREB, cAMP-responsive element binding protein; COX-2, cyclooxygenase-2; IL-6, interleukin-6; NF-κB, nuclear factor-κB; Ni, nickel; ROS, reacti
Keywords: COX-2، cyclooxygenase-2; Caffeine; Anti-inflammatory; LPS; NF-κB; MAPKsNF-κB, nuclear factor kappa B; MAPKs, mitogen-activated protein kinases; LPS, lipopolysaccharide; NO, nitric oxide; iNOS, nitric oxide synthase; COX-2, cyclooxygenase-2; IL, interleukin; IKK, IκB kinase; IκB,
Keywords: COX-2، cyclooxygenase-2; ADI, acceptable daily intake; ADD, average daily dose; BW, body weight; CAC, codex alimentarius commission; C, concentration; CR, consumption rate; COX-2, cyclooxygenase-2; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; EFSA, Europe
HuR translocation to the cytoplasm of cancer cells in actin-independent manner
Keywords: COX-2، cyclooxygenase-2; HuR, human antigen R; ARE, AU-rich element; 3â²-untranslated region (3â²-UTR); Latrunculin A (Lat.A); Blebbistatin (blebbistat); Human Angiotensin II (Ang.II); COX-2, cyclooxygenase-2;
Resolvin D1 down-regulates CYP1A1 and PTGS2 gene in the HUVEC cells treated with benzo(a)pyrene
Keywords: COX-2، cyclooxygenase-2; AhR, aryl hydrocarbon receptor; BaP, benzo(a)pyrene; Bbf, benzo(b)fluoranthene; Bkf, benzo(k)fluoranthene; COX-2, cyclooxygenase-2; cPGES, cytosolic prostaglandin E2 synthase; CYP1A1, cytochrome P450 1 A1; DHA, docosahexaenoic acid; FA, fatty acids; GSTM1
Traditional Chinese medicine Guizhi Fuling capsule used for therapy of dysmenorrhea via attenuating uterus contraction
Keywords: COX-2، cyclooxygenase-2; GZFLC, Guizhi Fuling capsule; PGF2α, prostaglandin F2α; NO, nitric oxide; COX-2, cyclooxygenase-2; OTR, oxytocin receptor; PL, paeonol; CA, cinnamic aldehyde; PGG, 1,2,3,4,6-penta-O-galloyl-beta-d-glucopyranose; NC, normal control group; MC, model control
The protective effect of total phenolics from Oenanthe Javanica on acute liver failure induced by D-galactosamine
Keywords: COX-2، cyclooxygenase-2; TPOJ, Total Phenolics from Oenanthe Javanica; TCM, Traditional Chinese Medicine; D-GalN, D-Galactosamine; iNOS, Nitric Oxide Synthase; COX-2, Cyclooxygenase-2; SOD, Superoxide Dismutase; GPx, Glutathione Peroxidase; CAT, Catalase; MDA, Malondialdehyde; GS
Intestinal anti-inflammatory effect of the rhizome extracts of Menispermum dauricum DC. on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
Keywords: COX-2، cyclooxygenase-2; ANOVA, one-way analysis of variance; CD, Crohn's disease; COX-2, cyclooxygenase-2; ELISA, enzyme-linked immunosorbent assay; IBD, Inflammatory bowel disease; IFN-γ, interferon-γ; IL, interleukin; iNOS, inducible nitric oxide synthase; MPO, myeloperoxidase
Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice
Keywords: COX-2، cyclooxygenase-2; ALT, alanine aminotransaminase; CCl4, carbon tetrachloride; COX-2, cyclooxygenase-2; DBM, DNA binding domain mutant; ERK5, extracellular signal-regulated kinase 5; HBV, hepatitis B virus; LPS, lipopolysaccharide; NF-κB, nuclear factor κB; PARP, poly (ADP-
(7R,8S)-9-Acetyl-dehydrodiconiferyl alcohol inhibits inflammation and migration in lipopolysaccharide-stimulated macrophages
Keywords: COX-2، cyclooxygenase-2; (7R,8S)-9-Acetyl-dehydrodiconiferyl alcohol; Lipopolysaccharide; Raw264.7; Inflammation; Migration; SrcADDA, (7R,8S)-9-acetyl-dehydrodiconiferyl alcohol; COX-2, cyclooxygenase-2; FAK, focal adhesion kinase; iNOS, inducible nitric oxide synthase; l-NMMA, N
Evaluation of chemopreventive effects in colitis-associated colon tumourigenesis and oral toxicity of the lipophilic epigallocatechin gallate-docosahexaenoic acid
Keywords: COX-2، cyclooxygenase-2; EGCG; EGCG-DHA; Subchronic toxicity; TumourigenesisEGCG, epigallocatechin-3-gallate; EGCG-DHA, epigallocatechin gallate-docosahexaenoic acid; AOM, azoxymethane; DSS, dextran sulphate sodium; COX-2, cyclooxygenase-2
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling
Keywords: COX-2، cyclooxygenase-2; COX-2, cyclooxygenase-2; ELISA, enzyme-linked immunosorbent assay; EMSA, electrophoretic mobility shift assay; ERK1/2, extracellular regulated kinase1/2; HCB, hexachlorobenzene; IκBα, inhibitor of NF-κB; IKK, inhibitor of nuclear factor kappa-B kinase; IL
Apigenin inhibits COX-2, PGE2, and EP1 and also initiates terminal differentiation in the epidermis of tumor bearing mice
Keywords: COX-2، cyclooxygenase-2; AA, arachidonic acid; BCC, basal cell carcinoma; COX-2, cyclooxygenase-2; DAB, diaminobenzidine; DMBA, 7, 12-dimethylbenz[a]anthracene; DMSO, dimethyl sulfoxide; EP1, prostaglandin E receptor subtype 1; EP2, prostaglandin E receptor subtype 2; FI, fold in
Isolates of Alpinia officinarum Hance as COX-2 inhibitors: Evidence from anti-inflammatory, antioxidant and molecular docking studies
Keywords: COX-2، cyclooxygenase-2; COX-2, cyclooxygenase-2; A. officinarum, Alpinia officinarum; Glide, grid-based ligand docking with energetics; DPPH, 1,1-diphenyl-2-picylhydrazyl; ROS, reactive oxygen species; RNS, reactive nitrogen species; MEAO, methanolic extract of A. officinarum; P
Iron and a mixture of DHA and EPA supplementation, alone and in combination, affect bioactive lipid signalling and morbidity of iron deficient South African school children in a two-by-two randomised controlled trial
Keywords: COX-2، cyclooxygenase-2; ALOX-15, arachidonate lipoxygenase-15; COX-2, cyclooxygenase-2; DHA, docosahexaenoic acid; DMT1, divalent metal transporter; EPA, eicosapentaenoic acid; GPx-4, glutathione peroxidase-4; HDHA, hydroxydocosahexaenoic acid; HEPE, hydroxyeicosapentaenoic acid
Antiinflammatory and immunomodulatory activity of an ethanolic extract from the stem bark of Terminalia catappa L. (Combretaceae): In vitro and in vivo evidences
Keywords: COX-2، cyclooxygenase-2; COX-2, Cyclooxygenase-2; CINC-1, cytokine-induced neutrophil chemoattractant-1; ETCB, ethanolic extract of the stem bark of T. catappa, GSH, glutathione; IBD, inflammatory bowel disease; iNOS, inducible nitric oxide synthase; IL, interleukin; LOQ, limit o
The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases
Keywords: COX-2، cyclooxygenase-2; C646 (PubChemCID: 1285941); SAHA (PubChemCID: 5311)HAT, histone acetyltransferase; HATi, HAT inhibitor; HDAC, histone deacetylase; PCAF, P300/CBP-associated factor; MOZ, monocytic leukemic zinc finger; COX-2, cyclooxygenase-2; NF-κB, nuclear factor kappa
Celecoxib antagonizes the cytotoxicity of oxaliplatin in human esophageal cancer cells by impairing the drug influx
Keywords: COX-2، cyclooxygenase-2; COX-2, cyclooxygenase-2; CTR1, copper transporter 1; FCM, flow cytometry; FITC, fluorescein isothiocyanate; ICP-MS, inductively coupled plasma mass spectroscopy; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NSAIDs, nonsteroidal anti-