Keywords: COX2، cyclooxygenase 2; ActB, β-actin; Akt, protein kinase B; COX2, cyclooxygenase 2; ERK, extracellular signal-regulated kinase; FAK, focal adhesion kinase; GPx, glutathione peroxidase; IκBα, NF-κB inhibitor α; JNK, c-Jun N-terminal kinase; MDA, malondialdehyde; NF-κB, nuclear
مقالات ISI COX2، cyclooxygenase 2 (ترجمه نشده)
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Keywords: COX2، cyclooxygenase 2; BM, basement membrane; CAFs, cancer-associated fibroblasts; CAMs, cell adhesion molecules; CAT, collective amoeboid transition; CCL2, chemokine (C–C motif) ligand 2; CCR3, chemokine receptor 3; Col, collagen; COX2, cyclooxygenase 2; CSF-1, chemokine colon
Keywords: COX2، cyclooxygenase 2; COX2, cyclooxygenase 2; CT, threshold cycle; DNT, developmental neurotoxicity; GD, gestational day; Gfap, glial fibrillary acidic protein; Mbp, myelin basic protein; Olig2, oligodendrocyte lineage transcription factor 2; PND, postnatal day; PTU, 6-propyl-
Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy
Keywords: COX2، cyclooxygenase 2; bFGF, basic fibroblast growth factor; CAF, cancer-associated fibroblast; CCL2/MCP1, chemokine ligand 2; CCR2, chemokine (C–C motif) receptor 2; COX2, cyclooxygenase 2; CSC, cancer stem-like cells; CSF-1, colony stimulating factor 1; CTLA4, cytotoxic T lym
Endometriosis as a detrimental condition for granulosa cell steroidogenesis and development: From molecular alterations to clinical impact
Keywords: COX2، cyclooxygenase 2; AMH, antimullerian hormone; ART, assisted reproduction technology; BMP, Bone morphogenetic protein; BMPR1, bone morphogenetic protein receptor type 1A; hCG, human chorionic gonadotropin; COX2, cyclooxygenase 2; E2, 17β-estradiol; ER, estrogen receptor; ER
Age-Associated Increase in Skin Fibroblast–Derived Prostaglandin E2 Contributes to Reduced Collagen Levels in Elderly Human Skin
Keywords: COX2، cyclooxygenase 2; COX2, cyclooxygenase 2; ECM, extracellular matrix; EIA, enzyme immunoassay; PGE2, prostaglandin E2; PTGES, prostaglandin E synthase
Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation
Keywords: COX2، cyclooxygenase 2; CD, Crohn's disease; COX2, cyclooxygenase 2; DSS, dextran sodium sulfate; ELISA, enzyme linked immunosorbent assay; ERK, extracellular signal-regulated kinase; GC, glucocorticoid; HPLC, high pressure liquid chromatography; IBD, inflammatory bowel disease;
Rutin has intestinal antiinflammatory effects in the CD4+ CD62L+ T cell transfer model of colitis
Keywords: COX2، cyclooxygenase 2; AP, alkaline phosphatase; ConA, concanavalin A; COX2, cyclooxygenase 2; CXCL1, chemokine (C-X-C motif) ligand 1; DAI, disease activity index; DSS, dextran sulfate sodium; IBD, inflammatory bowel disease; IκB-α, nuclear factor of kappa light polypeptide ge
Exposure of Wistar rats to 24-h psycho-social stress alters gene expression in the inferior colliculus
Keywords: COX2، cyclooxygenase 2; ABR, auditory brainstem response; ACTH, adrenocorticotropic hormone (ACTH); cFos, FBJ osteosarcoma viral oncogene; Cox2, cyclooxygenase 2; Ct, crossing threshold; DPOAE, distortion product otoacoustic emission; IC, inferior colliculus; iNos, nitric oxide
Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: Involvement of the adaptive antioxidant response
Keywords: COX2، cyclooxygenase 2; BSA, bovine serum albumin; C/EBPα, CCAAT-enhancer-binding protein α; CM-H2DCFDA, 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate, acetyl ester; COX2, cyclooxygenase 2; DMEM, Dulbecco’s modified Eagle’s medium; FBS, fetal bovine serum; GC
Growth factor signaling enhances aromatase activity of breast cancer cells via post-transcriptional mechanisms
Keywords: COX2، cyclooxygenase 2; PI3K, phosphatidylinositol 3-kinase; Akt, protein kinase B; MAPK, mitogen activated protein kinase; COX2, cyclooxygenase 2; PGE2, prostaglandin E2; EP, PGE2 receptor; ER, estrogen receptor; EGF, epidermal growth factor; TGFα, transforming growth factor α;
In vitro and in vivo effects of a cyclooxygenase-2 inhibitor nimesulide analog JCC76 in aromatase inhibitors-insensitive breast cancer cells
Keywords: COX2، cyclooxygenase 2; AI, aromatase inhibitor; PI3K, phosphatidylinositol 3-kinase; PDK, phosphoinositide-dependent kinase; AKt, protein kinase B; MAPK, mitogen activated protein kinase; COX2, cyclooxygenase 2; NSAIDs, Non-steroidal anti-inflammatory drugs; ER, estrogen recept
Pretreatment by low-dose fibrates protects against acute free fatty acid-induced renal tubule toxicity by counteracting PPARα deterioration
Keywords: COX2، cyclooxygenase 2; AST, aspartate amino transferase; ALT, alanine transaminase; BSA, bovine serum albumin; COX2, cyclooxygenase 2; FAON, free fatty acid overload nephropathy; FATP, fatty acid transport protein; FFA, free fatty acid; Fibrates, fibric acid derivatives; GAPDH,
Role of prostaglandin E2 in peptidoglycan mediated iNOS expression in mouse peritoneal macrophages in vitro
Keywords: COX2، cyclooxygenase 2; iNOS, inducible nitric oxide synthase; COX2, cyclooxygenase 2; PGN, peptidoglycan; PGE2, prostaglandin E2Macrophage; Inducible nitric oxide synthase; Cyclooxygenase 2; Peptidoglycan; Prostaglandin E2
COX-2 inhibitor nimesulide analogs are aromatase suppressors in breast cancer cells
Keywords: COX2، cyclooxygenase 2; AIs, aromatase inhibitors; PDK, phosphoinositide-dependent kinase; COX2, cyclooxygenase 2; NSAIDs, non-steroidal anti-inflammatory drugs; ER, estrogen receptor; Her2, human epidermal growth factor receptor; LTED, long-term estrogen deprivationBreast cance
Avian influenza H5N1 virus induces cytopathy and proinflammatory cytokine responses in human astrocytic and neuronal cell lines
Keywords: COX2، cyclooxygenase 2; neurodegenerative disease; cytokine; influenza virus; neuroinflammation; viral infectionCCL2, chemokine (C–C motif) ligand 2; COX2, cyclooxygenase 2; DIG, digoxigenin; FBS, fetal bovine serum; GFAP, glial fibrillary acidic protein; IFN, interferon; IL, in
Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis
Keywords: COX2، cyclooxygenase 2; ADRP, adipose differentiation-related protein; bZIP, basic-region leucine zipper; CNC, cap'n'collar; COX2, cyclooxygenase 2; CYP, cytochrome P450; GCLC, glutamate–cysteine ligase catalytic; GCLM, glutamate–cysteine ligase modifier; GSSG, glutathione (oxid
Celecoxib potently inhibits TNFα-induced nuclear translocation and activation of NF-κB
Keywords: COX2، cyclooxygenase 2; COX2, cyclooxygenase 2; DMSO, dimethyl sulfoxide; ELISA, enzyme-linked immunosorbent assay; MAP kinase, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; FBS, fetal bovine serum; IκBa, inhibitor of NF-κB; IKK, IκB kinase; IL-1,
Effect of flavonoids on rat splenocytes, a structure–activity relationship study
Keywords: COX2، cyclooxygenase 2; ConA, concanavalin A; COX2, cyclooxygenase 2; DMSO, dimethyl sulfoxide; FACS, fluorescence-activated cell sorting; IFN-γ, interferon gamma; IL, interleukin; iNOS, inducible nitric oxide synthase; TNF-α, tumor necrosis factor alphaLymphocyte; Flavonoid; Vi
The myocardial JAK/STAT pathway: From protection to failure
Keywords: COX2، cyclooxygenase 2; AngII, angiotensin II; AT1, AT1 receptor; Bcl-xL, Basal cell lymphoma-extra large; CNTF, ciliary neurotrophic factor; COX2, cyclooxygenase 2; CT-1, cardiotrophin-like cytokine; eNOS, endothelial nitric oxide synthase; ERK, extracellular signal related kin
Coevolution between cannabinoid receptors and endocannabinoid ligands
Keywords: COX2، cyclooxygenase 2; ABHD4, abhydrolase domain-containing protein 4; AEA, anandamide; CB1, cannabinoid receptor 1; CB2, cannabinoid receptor 2; COX2, cyclooxygenase 2; DAGLα, diacylglycerol lipase alpha; DAGLβ, diacylglycerol lipase beta; FAAH, fatty acid amide hydrolase; ML,