Keywords: HCC; hepatocellular carcinoma; NAFLD; non-alcoholic fatty liver disease; IMS; imaging mass spectrometry; MALDI; matrix-assisted laser desorption/ionization; LPCAT; lysophosphatidylcholine acyltransferase; PCA; principal component analysis; cPLA2α; cytoso
مقالات ISI (ترجمه نشده)
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Blockage of cytosolic phospholipase A2 alpha sensitizes aggressive breast cancer to doxorubicin through suppressing ERK and mTOR kinases
Keywords: Breast cancer; cPLA2α; mTOR; ERK; Doxorubicin;
Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress
Keywords: AA; arachidonic acid; AMPK; AMP-dependent protein kinase; ATGL; adipose triglyceride lipase; cPLA2α; cytosolic group IVA PLA2; CPT1; carnitine O-palmitoyltransferase 1; CPT1A; the liver isoform of CPT1; DGAT1; diacylglycerol acyltransferase 1; DHA; docos
Regulation of calcium release from the endoplasmic reticulum by the serine hydrolase ABHD2
Keywords: Calcium; Endoplasmic reticulum; Mitochondria; Serine hydrolase; Pyrrophenone; ABHD2; Cell death; H2O2; ABHD; α/β-hydrolase domain-containing; cPLA2α; cytosolic phospholipase A2α; CEPIA; calcium-measuring organelle-entrapped protein indicators; CyD; cy
Lipidomics in translational research and the clinical significance of lipid-based biomarkers
Keywords: 5-HETE; 5-hydroxyicosatetraenoic acid; 12-HETE; 12-hydroxyicosatetraenoic acid; 15-HETE; 15-hydroxyicosatetraenoic acid; aa; diacyl; ae; acyl-alkyl; ACs; acylcarnitines; ACOG; The American College of Obstetricians and Gynecologists; AD; Alzheimer's dise
Off-target effect of the cPLA2α inhibitor pyrrophenone: Inhibition of calcium release from the endoplasmic reticulum
Keywords: cPLA2α; Calcium; Pyrrophenone; Endoplasmic reticulum; Mitochondria; cPLA2α; cytosolic phospholipase A2α; ER; endoplasmic reticulum; DMEM; Dulbecco's Modified Eagle's Medium; MPTP; mitochondrial permeability transition pore; IMLF; immortalized mouse lun
Cytosolic phospholipase A2α increases proliferation and de-differentiation of human renal tubular epithelial cells
Keywords: cPLA2α; Phospholipase A2; Arachidonic acid; HK-2; Proximal tubule; E-cadherin;
Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity
Keywords: ADM; adipogenic differentiation medium; AA; arachidonic acid; cPLA2α; cytosolic group IVA phospholipase A2α; MCE; mitotic clonal expansion; ASCs; adipose stem cell; MEFs; mouse embryonic fibroblast; HFD; high fat diet; MTT; 3-(4.5-dimethylthiazol-2-yl)-
Endogenous secreted phospholipase A2 group X regulates cysteinyl leukotrienes synthesis by human eosinophils
Keywords: Eosinophil; leukotriene; phospholipase A2; mitogen-activated kinase; asthma; allergy; 5-LO; 5-Lipoxygenase; cPLA2α; Cytosolic phospholipase A2α; CysLT; Cysteinyl leukotriene; DMSO; Dimethyl sulfoxide; ER; Endoplasmic reticulum; ERK1/2; Extracellular-sig
A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced obesity but PAF/PAF receptor signaling does not contribute to the development of obesity-induced chronic inflammation
Keywords: ATGL; adipose triglyceride lipase; AUC; area under the curve; BM; bone marrow; BMM; bone marrow-derived macrophage; COX-2; cyclooxygenase 2; c-PAF; 1-O-hexadecyl-2-N-methylcarbamoyl-sn-glycero-3-phosphocholine; cPLA2α; cytosolic phospholipase A2α; FACS;
Extra-hepatic metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2α and SOAT1 followed by selective efflux to HDL
Keywords: 7-Ketocholesterol; 7-Ketocholesterol fatty acid ester; SOAT1; cPLA2α; HDL; Cultured RPE cell;
Investigations on the metabolic stability of cytosolic phospholipase A2α inhibitors with 1-indolylpropan-2-one structure
Keywords: cPLA2α; cytosolic phospholipase A2α; CYP450; cytochrome P450; SDR; short-chain dehydrogenase/reductase; AKR; aldo-keto-reductase; HPLC; high performance liquid chromatography; MS; mass spectrometry; ESI; electrospray ionization; NMR; nuclear magnetic
Cytosolic phospholipase A2α sustains pAKT, pERK and AR levels in PTEN-null/mutated prostate cancer cells
Keywords: cPLA2α; AKT; ERK; AR; PTEN; Prostate cancer;
Pharmacophore-based discovery of a novel cytosolic phospholipase A2α inhibitor
Keywords: Cytosolic phospholipase A2α; cPLA2α; Inflammation; Pharmacophore modeling; Virtual screening;
cPLA2α-mediated actin rearrangements downstream of the Akt signaling is required for Cronobacter sakazakii invasion into brain endothelial cells
Keywords: cPLA2α; Cronobacter sakazakii; Brain endothelial cells; Meningitis; Akt; Actin rearrangements;
Association with actin mediates the EGTA-resistant binding of cytosolic phospholipase A2-α to the plasma membrane of activated platelets
Keywords: Platelet; Phospholipase A2; Plasma membrane; Actin; cPLA2α; Cytosolic phospholipase A2-α; PLA2; phospholipase A2; iPLA2; Calcium-independent phospholipases A2; sPLA2; Secretory phospholipases A2; AA; Arachidonic acid; TxA2; Thromboxane A2; CalB; Calcium
Oxidative stress and arachidonic acid mobilization
Keywords: AA; arachidonic acid; PLA2; phospholipase A2; iPLA2; calcium-independent phospholipase A2 activity (undefined molecular identity); iPLA2-VIA; Group VIA phospholipase A2; cPLA2α; cytosolic Group IVA phospholipase A2; cPLA2γ; Group IVC phospholipase A2; s
Identification and molecular cloning of a gene encoding Phospholipase A2 (plaA) from Aspergillus nidulans
Keywords: cPLA2α; cytosolic phospholipase A2α; Phospholipase A2; Aspergillus nidulans; plaA; Fungi; Phospholipid;