
Molecular interaction of the first 3 enzymes of the de novo pyrimidine biosynthetic pathway of Trypanosoma cruzi
Keywords: CPSII; carbamoyl-phosphate synthetase II; ATC; aspartate transcarbamoylase; DHO; dihydroorotase; CAD; CPSII-DHO-ATC fusion enzyme; UMP; uridine 5â²-monophosphate; SBDD; structure-based drug design; De novo pyrimidine biosynthetic pathway; Carbamoyl-phosp