Keywords: گوانوزین مونوفسفات سیکل (cGMP); Nitric oxide synthase (NOS); Cyclic guanosine monophosphate (cGMP); Soluble guanylate cyclase (sGC); Particulate guanylyl cyclase (pGC); Natriuretic peptide; Phosphodiesterase (PDE); cGMP-dependent protein kinase (PKG)