
Roles of hinge region, loops 3 and 4 in the activation of Escherichia coli cyclic AMP receptor protein
Keywords: cAMP; 3â²,5â²-cyclic adenosine monophosphate; PKA; protein kinase A; Epac; exchange protein directly activated by cAMP; CRP; cAMP receptor protein; CNGC; cyclic nucleotide-gated ion channels; WT; wild-type; TEK100; 50Â mM Tris 1Â mM EDTA and 100Â mM KCl