Keywords: مهار Cyclooxygenase; ACh; acetylcholine; AFD; African descent; AUC; area under the curve; CAU; Caucasian; COXib; cyclooxygenase inhibition; ED50; half-maximal effective dose; IQR; interquartile range; LDU; laser Doppler units; MAP; mean arterial pressure; Mdn; median; NFCI; n
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Keywords: مهار Cyclooxygenase; Flavonoids; Anti-angiogenesis; Antioxidant; Cytotoxicity; Cyclooxygenase inhibition; Molecular docking; VEGFR and EGFR
Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidine derivatives bearing thiazolidinone moiety as anti-inflammatory agents
Keywords: مهار Cyclooxygenase; Pyrazolo[3,4-d]pyrimidines; Thiazolidinones; Anti-inflammatory activity; Ulcerogenic potential; Cyclooxygenase inhibition;
Synthesis, COX-1/2 inhibition activities and molecular docking study of isothiazolopyridine derivatives
Keywords: مهار Cyclooxygenase; Isothiazolopyridine; Cyclooxygenase inhibition; Molecular docking;
Design, synthesis and biological screening of some novel celecoxib and etoricoxib analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile
Keywords: مهار Cyclooxygenase; Pyrazoline; Cyanopyridine; Cyclooxygenase inhibition; Anti-inflammatory;
Design, synthesis and biological screening of new 4-thiazolidinone derivatives with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile
Keywords: مهار Cyclooxygenase; Thiazolidinone; Cyclooxygenase inhibition; Anti-inflammatory; Molecular modeling
Cyclooxygenase inhibition and rosuvastatin-induced vascular protection in the setting of ischemia-reperfusion: A human in vivo study
Keywords: مهار Cyclooxygenase; Acetylsalicylic acid (PubChem CID: 2244); Celecoxib (PubChem CID: 2662); Ibuprofen (PubChem CID: 3672); Rosuvastatin (PubChem CID: 446157); Non-steroidal anti-inflammatory drugs; Flow-mediated dilation; Endothelial dysfunction; Cyclooxygenase inhibition;
Seasonal variation in the cyclooxygenase inhibitory activities of four South African medicinal bulbs
Keywords: مهار Cyclooxygenase; Anti-inflammatory; Cyclooxygenase inhibition; Medicinal bulbs; Seasonal variation
A diazen-1-ium-1,2-diolated nitric oxide donor ester prodrug of 3-(4-hydroxymethylphenyl)-4-(4-methanesulfonylphenyl)-5H-furan-2-one: Synthesis, biological evaluation and nitric oxide release studies
Keywords: مهار Cyclooxygenase; Rofecoxib; Diazen-1-ium-1-2-diolate; Ester prodrug; Nitric oxide donor; Cyclooxygenase inhibition; Vascular effects; Anti-inflammatory activity
Impact of NSAIDs on cardiovascular risk and hypertension
Keywords: مهار Cyclooxygenase; Cyclooxygenase inhibition; Non-steroidal anti-inflammatory drugs; Hypertension; Cardiovascular events;
In vitro antimicrobial, anthelmintic and cyclooxygenase-inhibitory activities and phytochemical analysis of Leucosidea sericea
Keywords: مهار Cyclooxygenase; Anthelmintic; Antimicrobial; Cyclooxygenase inhibition; Leucosidea sericea; Phytochemical analysis
Celecoxib prodrugs possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Synthesis, biological evaluation and nitric oxide release studies
Keywords: مهار Cyclooxygenase; Nitric oxide donors; Cyclooxygenase inhibition; Anti-inflammatory activity;
Peripheral μ-, κ- and δ-opioid receptors mediate the hypoalgesic effect of celecoxib in a rat model of thermal hyperalgesia
Keywords: مهار Cyclooxygenase; Hypoalgesia; Celecoxib; Hargreave's method; Opioid receptors; Cyclooxygenase inhibition;
Anthocyanin content, antioxidant, anti-inflammatory and anticancer properties of blackberry and raspberry fruits
Keywords: مهار Cyclooxygenase; Blackberry; Raspberry; Rubus jamaicensis; Rubus rosifolius; Rubus racemosus; Rubus acuminatus; Rubus idaeus; Lipid peroxidation; Cyclooxygenase inhibition; Anticancer; Biodiversity; Interspecies differences; Cultivar differences; Food analysis; Food compo
In vitro pharmacological evaluation and phenolic content of ten South African medicinal plants used as anthelmintics
Keywords: مهار Cyclooxygenase; Anthelmintic; Antimicrobial; Cyclooxygenase inhibition; Phenolic content; South African medicinal plants; Tannin
Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant
Keywords: مهار Cyclooxygenase; Airway hyperresponsiveness; Allergic mouse model; Eicosanoids; Cell infiltration; Chemokines; Cyclooxygenase inhibition; Cytokines
Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: Synthesis, biological evaluation and nitric oxide release studies
Keywords: مهار Cyclooxygenase; NSAIDs; Nitrate and diazen-1-ium-1,2-diolate nitric oxide donor ester prodrugs; Cyclooxygenase inhibition; Anti-inflammatory activity
Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies
Keywords: مهار Cyclooxygenase; NONO-coxib ester prodrugs; Diazen-1-ium-1,2-diolate nitric oxide donor; Cyclooxygenase inhibition; Anti-inflammatory activity
Synthesis and biological evaluation of 4,5-diphenyloxazolone derivatives on route towards selective COX-2 inhibitors
Keywords: مهار Cyclooxygenase; 4,5-Diphenyloxazolone; Cyclooxygenase inhibition; COX-1; COX-2; Docking
Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies
Keywords: مهار Cyclooxygenase; 1,5-Diarylpyrazoles; NONO-coxib ester prodrugs; Diazen-1-ium-1,2-diolate nitric oxide donor; Cyclooxygenase inhibition; Anti-inflammatory activity
Terpenoids from Stinking toe (Hymneae courbaril) fruits with cyclooxygenase and lipid peroxidation inhibitory activities
Keywords: مهار Cyclooxygenase; Hymenaea courbaril; Sucrose; Diterpenoids; Cyclooxygenase inhibition; Lipid peroxidation inhibition
Synthesis and biological evaluation of methanesulfonamide analogues of rofecoxib: Replacement of methanesulfonyl by methanesulfonamido decreases cyclooxygenase-2 selectivity
Keywords: مهار Cyclooxygenase; Cyclooxygenase inhibition; Rofecoxib analogues; Methanesulfonamido pharmacophore
Biological activities of cycloart-23-ene-3,25-diol isolated from the leaves of Trichilia dregeana
Keywords: مهار Cyclooxygenase; Cycloartane triterpenoids; Cyclooxygenase inhibition; Traditional medicine; Trichilia dregeana
O2-Acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO–NSAIDs): Synthesis, nitric oxide release, and biological evaluation studies
Keywords: مهار Cyclooxygenase; Nitric oxide donors; Diazeniumdiolates; Non-ulcerogenic NSAIDs; Anti-inflammatories; Cyclooxygenase inhibition
Anolignan B: A bioactive compound from the roots of Terminalia sericea
Keywords: مهار Cyclooxygenase; Antibacterial; Anolignan B; Cyclooxygenase inhibition; Combretaceae; Terminalia sericea
Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors
Keywords: مهار Cyclooxygenase; Cyclooxygenase inhibition; Propenone moiety; Azido pharmacophore
Cyclooxygenase inhibition attenuates endotoxin-induced spatial learning deficits, but not an endotoxin-induced blockade of long-term potentiation
Keywords: مهار Cyclooxygenase; Endotoxins; Synaptic plasticity and learning; Cyclooxygenase inhibition; Lipopolysaccharide; Long-term potentiation;
Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors
Keywords: مهار Cyclooxygenase; N-Acetyl-2-(or 3-)carboxymethylbenzenesulfonamides; Cyclooxygenase inhibition; Anti-inflammatory activity