دانلود مقالات ISI درباره CYP، سیتوکروم P-450 + ترجمه فارسی

انقباض قلبی در تلهست از قطب جنوب توسط نیتریت بوسیله یون سدیم اکسیداز و سیتوکروم پلاتین 450 نیتریت ردوکتاز

Cardiac contractility in Antarctic teleost is modulated by nitrite through xanthine oxidase and cytochrome p-450 nitrite reductase

Keywords: CYP، سیتوکروم P-450; Nitrite; Nitric oxide; Antarctic teleosts; Icefish; Xanthine oxidase; Cytochrome P-450NO, nitric oxide; NOS, nitric oxide synthase; XO, xanthine oxidase; CYP, cytochrome P-450; Hb, haemoglobin; Mb, myoglobin; CO, cardiac output; HR, heart rate; SV, stroke

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Simultaneous determination of gefitinib and its major metabolites in mouse plasma by HPLC–MS/MS and its application to a pharmacokinetics study

Keywords: CYP، سیتوکروم P-450; TKI, tyrosine kinase inhibitor; NSCLC, non-small cell lung cancer; LC–MS/MS, liquid chromatography–tandem mass spectrometry; EGFR, epidermal growth factor receptor; MRM, multiple reaction monitoring; CYP, cytochrome P-450; PK, pharmacokinetic; ESI, electr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Chitosan oligosaccharides reduce acetaminophen-induced hepatotoxicity by suppressing CYP-mediated bioactivation

Keywords: CYP، سیتوکروم P-450; ALT, alanine aminotransferase; APAP, acetaminophen; COS, chitosan oligosaccharide; CYP, cytochrome P-450; DME, drug-metabolizing enzyme; EDTA, ethylenediaminetetraacetic acid; GSH, reduced glutathione; GST, glutathione S-transferase; HO-1, heme oxygenase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Environmental and occupational pesticide exposure and human sperm parameters: A systematic review

Keywords: CYP، سیتوکروم P-450; ABM, abamectin; CDCCA, cis-3-(2,2,dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid; CI, 95% confidence interval; CYP, cytochrome P-450; DAP, dialkylphosphate; DCCA, 3-(2,2,dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid; DDT, dichlorodiphen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Platelet Function Tests in Clinical Cardiology : Unfulfilled Expectations

Keywords: CYP، سیتوکروم P-450; aggregation; PCI; platelets; thrombosisAA, arachidonic acid; ACS, acute coronary syndrome(s); ADP, adenosine diphosphate; AMI, acute myocardial infarction; CYP, cytochrome P-450; DAPT, dual antiplatelet therapy; DES, drug-eluting stent(s); HR, hazard rati

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Danshen–Gegen decoction protects against hypoxia/reoxygenation-induced apoptosis by inhibiting mitochondrial permeability transition via the redox-sensitive ERK/Nrf2 and PKCɛ/mKATP pathways in H9c2 cardiomyocytes

Keywords: CYP، سیتوکروم P-450; ABT, 1-aminotriazole; Akt, alpha-serine threonine kinase; BAD, Bcl-2 associated death promoter; CYP, cytochrome P-450; ERK, extracellular signal regulated kinase; DCFDA, 2′-7′-dichlorofluorescein diacetate; DG, Danshen–Gegen; DMTU, dimethylthiouracil; GCL

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Individualized dosing regimens in children based on population PKPD modelling: Are we ready for it?

Keywords: CYP، سیتوکروم P-450; CYP, cytochrome P-450; LC–MS/MS, liquid chromatography with tandem mass spectrometry; MAC, minimum alveolar concentration; PIP, paediatric investigation plan; PUMA, Paediatric-Use Marketing Authorisation; TI Pharma, Top Institute Pharma; UGT, uridine 5′-d

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Determination of cut-off levels for on-clopidogrel platelet aggregation based on functional CYP2C19 gene variants in patients undergoing elective percutaneous coronary intervention

Keywords: CYP، سیتوکروم P-450; ACS, acute coronary syndrome; ADP, adenosine diphosphate; ADP-PR area, ADP-induced platelet reactivity area; ADP-PR max, ADP-induced platelet reactivity maximum aggregation; CAD, coronary artery disease; CYP, cytochrome P-450; LTA, light transmittent aggr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Calcium-Channel Blockers Do Not Alter the Clinical Efficacy of Clopidogrel After Myocardial Infarction : A Nationwide Cohort Study

Keywords: CYP، سیتوکروم P-450; calcium-channel blocker; clopidogrel; effect modification; interaction; myocardial infarction; strokeATC, Anatomical Therapeutic Chemical; CCB, calcium-channel blocker; CYP, cytochrome P-450; ICD, International Classification of Diseases; MI, myocardial i

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

In vitro modulation of ABCB1/P-glycoprotein expression by polyphenols from Mangifera indica

Keywords: CYP، سیتوکروم P-450; Calcein-AM, calcein acetoxymethylester; CsA, cyclosporine A; CYP, cytochrome P-450; CTCH, catechin; DRB, 1-d-ribofuranosylbenzimidazole; GA, gallic acid; MG, mangiferin; MSBE, mango stem bark extract; NTR, norathyriol; P-gp, P-glycoprotein; QCT, quercetin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Evaluation of the binding orientations of testosterone in the active site of homology models for CYP2C11 and CYP2C13

Keywords: CYP، سیتوکروم P-450; CYP, cytochrome P-450; 3-D, 3-dimensional; IFD, induced-fit dockingCYP2C; Homology modeling; Testosterone metabolism; Substrate docking; CYP binding site

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

New aspects of the role of hydroxyeicosatetraenoic acids in cell growth and cancer development

Keywords: CYP، سیتوکروم P-450; AA, arachidonic acid; COX, cyclooxygenase; CYP, cytochrome P-450; DiHETE, dihydroxyeicosatetraenoic acids; EGF, epidermal-growth factor; ERK, extracellular signal-regulated kinases; HETE, hydroxyeicosatetraenoic acid; HETrE, hydroxyeicosatrienoic acids; H

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Lipid peroxidation: Physiological levels and dual biological effects

Keywords: CYP، سیتوکروم P-450; 6-OHDA, 6-hydroxydopamine; 15d-PGJ2, 15-deoxy-delta(12,14)-prostaglandin-J2; ATF4, activating transcription factor 4; CEOOH, cholesteryl ester hydroperoxide; Ch, cholesterol; COX, cyclooxygenase; CYP, cytochrome P-450; DHA, docosahexaenoic acid (22:6); EP

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

Cell shape, cell–cell contact, cell–extracellular matrix contact and cell polarity are all required for the maximum induction of CYP2B1 and CYP2B2 gene expression by phenobarbital in adult rat cultured hepatocytes

Keywords: CYP، سیتوکروم P-450; apo, apolipoprotein; CAR, constitutive activator receptor; CYP, cytochrome P-450; EHS, Engelbreth-Holm-Swan; IDPN, 3,3′-iminodipropionitrile; PB, phenobarbital; TIC, type I collagen; TIVC, type IV collagen; UGT, UDP-glucuronosyltransferaseHepatocyte; Phen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Expression profile of liver genes in response to hepatotoxicants identified using a SAGE-based customized DNA microarray system

Keywords: CYP، سیتوکروم P-450; BPA, bisphenol A; CAR, constitutive androstane receptor; Cd, cadmium chloride; CT, carbon tetrachloride; CYP, cytochrome P-450; DEHP, di-(2-ethylhexyl) phthalate; E2, 17β-estradiol; EDC, endocrine-disrupting chemical; ER, estrogen receptor; IPA, ingenuity

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Mass spectrometric assay and physiological–pharmacological activity of androgenic neurosteroids

Keywords: CYP، سیتوکروم P-450; AED, antiepileptic drug; APCI, atmospheric pressure chemical ionization; AR, androgen receptor; CYP, cytochrome P-450; DHT, 5α-dihydrotestosterone; ECNCI, electron capture negative chemical ionization; GABA, γ-aminobutyric acid; GC, gas chromatography; 3α

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Nicotine and caffeine-mediated modulation in the expression of toxicant responsive genes and vesicular monoamine transporter-2 in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype in mouse

Keywords: CYP، سیتوکروم P-450; PD, Parkinson's disease; MPTP, 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine; CYP, cytochrome P-450; VMAT-2, vesicular monoamine transporter-2; GST, glutathione-S-transferase; RT-PCR, reverse transcription polymerase chain reaction; CDNB, 1-chloro-2, 4-din

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease

Keywords: CYP، سیتوکروم P-450; COPD, Chronic obstructive pulmonary disease; CYP, Cytochrome p-450; NAT2, N-acetyl transferase-2; RFLP, Restriction Fragment Length Polymorphism; SA, Slow acetylator; FA, Fast acetylatorChronic obstructive pulmonary disease; Detoxification; Cytochrome p-4

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Measurement of voriconazole in serum and plasma

Keywords: CYP، سیتوکروم P-450; CYP, cytochrome P-450; Cmax, maximum plasma concentration; AUC, area under the curve; LOD, limit of detection; LOQ, limit of quantitation; SD, standard deviation; CV, coefficient of variation; RT, ambient (room) temperature; EDTA, potassium ethylenediamin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Protective effect of Ocimum sanctum on 3-methylcholanthrene, 7,12-dimethylbenz(a)anthracene and aflatoxin B1 induced skin tumorigenesis in mice

Keywords: CYP، سیتوکروم P-450; AFB1, aflatoxin B1; AHH, aryl hydrocarbon hydroxylase; Alc. Ext., alcoholic extract of leaves of O. sanctum; CYP, cytochrome P-450; DMBA, dimethylbenzanthracene; ERD, ethoxyresorufin-O-deethylase; GGT, γ-glutamyl transpeptidase; GST-P, glutathione-S-trans

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of dietary fat on metabolism and DNA adduct formation after acute oral exposure of F-344 rats to fluoranthene

Keywords: CYP، سیتوکروم P-450; CYP, cytochrome P-450; FLA, fluoranthene; FLA 2, 3-diol, fluoranthene 2, 3-dihydrodiol; 2, 3 DFLA, trans-2, 3-dihydroxy-1, 10b-epoxy-1, 2, 3, 10b-tetrahydrofluoranthene; HPLC, high-performance liquid chromatography; 3(OH) FLA, 3-hydroxyfluoranthene; 8(OH)

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Skin tumorigenic potential of aflatoxin B1 in mice

Keywords: CYP، سیتوکروم P-450; AFB1, Aflatoxin B1; AHH, Aryl hydrocarbon hydroxylase; CYP, Cytochrome P-450; DMBA, dimethylbenzanthracene; ERD, Ethoxyresorufin-O-deethylase; GST, glutathione-S-transferase; HCC, hepatocellular carcinoma; LPO, Lipid peroxidation; MCA, 3-methylcholanthren

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Expression of glutathione S-transferases in fetal lung and liver tissue from parental strains and F1 crosses between C57BL/6 and BALB/c F1 mice following in utero exposure to 3-methylcholanthrene

Keywords: CYP، سیتوکروم P-450; AHH, aryl hydrocarbon hydroxylase activity; CDNB, 1-chloro-2,4-dinitrobenzene; Cyp, cytochrome P-450; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GST, glutathione S-transferase; MC, 3-methylcholanthrene; NAT, N-acetyltransferases; PAH, polycyclic aro

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

c-Jun N-Terminal Kinase Plays a Major Role in Murine Acetaminophen Hepatotoxicity

Keywords: CYP، سیتوکروم P-450; APAP, acetaminophen; ASO, antisense oligonucleotide; Cl2MBP, dichloromethylene-bisphosphonate; Con A, concanavalin A; COX IV, cytochrome oxidase IV; CYP, cytochrome p-450; DMSO, dimethyl sulfoxide; JNK, c-jun N-terminal kinase; LPS, lipopolysaccharide; NA

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2)

Keywords: CYP، سیتوکروم P-450; Coffee diterpenes; Cafestol; Kahweol; N-nitrosodimethylamine; PhIP; Metabolic enzymes; Antimutagenicity; Micronucleus; HepG2; AFB1, aflatoxin B1; B(a)P, benzo[a]pyrene; C + K, cafestol and kahweol; CDNB, 1-chloro-2,4-dinitrobenzene; CYP, cytochrome P-45

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Differentiation of In Vitro–Modified Human Peripheral Blood Monocytes Into Hepatocyte–like and Pancreatic Islet-like Cells

Keywords: CYP، سیتوکروم P-450; CSF-R, colony-stimulating factor receptor; CYP, cytochrome P-450; EGFP, enhanced green fluorescent protein; FGF, fibroblast growth factor; HCM, hepatocyte conditioning medium; ICM, islet cell conditioning medium; IL, interleukin; M-CSF, macrophage colony-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه