High risk of adrenal toxicity of N1-desoxy quinoxaline 1,4-dioxide derivatives and the protection of oligomeric proanthocyanidins (OPC) in the inhibition of the expression of aldosterone synthetase in H295R cells
Keywords: ALD, aldosterone; ATF-1, activating transcription factor-1; cDNA, complementary DNA; CREB, cyclic AMP response element binding protein; CYA, cyadox; CYP11B1, 11β-hydroxylase; CYP11B2, aldosterone synthase; DAB, 3′,3′-diaminobenzidine; DMSO, dimethyl sulfo