Keywords: Warfarin; Anticoagulation; Thromboembolism; CYP2C9; VKORC1; Surgery;
مقالات ISI (ترجمه نشده)
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Keywords: Body mass index; CYP2C9; CYP4F2; Gene-environment interaction; Major bleeding; VKORC1; Warfarin;
Keywords: Atrial fibrillation; CYP2C9; VKORC1; warfarin; polymorphism; stroke;
Keywords: VPA; valproic acid; FABP2; fatty acid binding protein 2; UGT1A6; uridine diphosphate glucuronosyltransferase family 1 member A6; UGT2B7; uridine diphosphate glucuronosyltransferase family 2 member B7; CYP2C9; cytochrome P450 family 2 subfamily C member 9;
Keywords: Chronic hypobaric hypoxia; CYP2C9; Hepatic metabolism; Ibuprofen; Pharmacokinetics
Keywords: CYP2C19; cytochrome P450 C19; CYP2C9; cytochrome P450 C9; CYP3A4; cytochrome P450 3A4; HERG; human ether-Ã -go-go-related gene; HPLC; high-pressure liquid chromatography; IKr; rapid component of delayed rectifier potassium current; IKur; ultrarapid acti
Keywords: Toremifene; Tamoxifen; Metabolite kinetics; Bioactivation; CYP2D6; CYP3A4; CYP2C9; Pharmacogenomics; PolymorphismsTOR, toremifene; TAM, tamoxifen; SERM, selective estrogen receptor modulator; SSRI, selective serotonin reuptake inhibitor; 4OH, 4-hydroxy; N
Keywords: Stroke; Warfarin; CYP2C9; VKORC1; Polymorphisms;
Keywords: Warfarin; Pharmacogenetics; CYP2C9; VKORC1; Meta analysis;
Keywords: CYP2C9; cytochrome P-450 variant 2C9; VKORC1; vitamin K epoxide reductase complex-1; SNP; single-nucleotide polymorphism; PCR; polymerase chain reaction; Warfarin; Microarray; SNP; Lateral flow cell; Saliva;
Keywords: Clopidogrel resistance; VASP; CYP2C19; ABCB1; CYP2C9
Interactions of casticin, ipriflavone, and resveratrol with serum albumin and their inhibitory effects on CYP2C9 and CYP3A4 enzymes
Keywords: Casticin; Ipriflavone; Resveratrol; serum albumin; CYP2C9; CYP3A4;
Celecoxib is a substrate of CYP2D6: Impact on celecoxib metabolism in individuals with CYP2C9*3 variants
Keywords: Celecoxib; CYP2C9; CYP2D6; Drug-drug interaction; Genetic polymorphism; Hydroxy celecoxib;
Farmacogenética de reacciones adversas a fármacos antiepilépticos
Keywords: Farmacogenética; Reacciones adversas a medicamentos; Fármacos antiepilépticos; CYP2C9; ABCC2; AntÃgeno leucocitario humano (HLA); Pharmacogenetics; Adverse drug reactions; Antiepileptic drugs; CYP2C9; ABCC2; Human leukocyte antigen (HLA);
Effects of UGT2B7, SCN1A and CYP3A4 on the therapeutic response of sodium valproate treatment in children with generalized seizures
Keywords: VPA; sodium valproate; FABP2; fatty acid binding protein 2; ABCB1; ATP binding cassette subfamily B member 1; ABCC2; ATP binding cassette subfamily C member 2; GABA; gamma-aminobutyric acid; ABAT; 4-aminobutyrate aminotransferase; GABR; GABA receptor; SCN
Weight and the vitamin K expoxide reductase 1 genotype primarily contribute to the warfarin dosing in pediatric patients with Kawasaki disease
Keywords: KD; Kawasaki disease; CAA; coronary artery aneurysm; GCAA; giant coronary artery aneurysm; INR; international normalized ratio; SNP; single nucleotide polymorphism; VKORC1; vitamin K expoxide reductase; CYP2C9; cytochrome P4502C9; BSA; body surface area;
Bleeding predictors in patients following venous thromboembolism treated with vitamin K antagonists: Association with increased number of single nucleotide polymorphisms
Keywords: Venous thromboembolism; Vitamin K antagonists; Acenocoumarol; Warfarin; Genetic polymorphisms; AF; atrial fibrillation; APOE; apolipoprotein E; AUC; area under the curve; CI; confidence interval; CRNM bleeding; clinically relevant non-major bleeding; CYP2
Different inhibitory effects of azole-containing drugs and pesticides on CYP2C9 polymorphic forms: An in vitro study
Keywords: CYP2C9; Polymorphism; Azole; Pesticide; Cytochrome b5; Drug-drug interactions;
CYP2C9, CYPC19 and CYP2D6 gene profiles and gene susceptibility to drug response and toxicity in Turkish population
Keywords: Genetic polymorphism; Turkish population; CYP2C9; CYP2C19; CYP2D6; Cytochrome P450;
A prospective study to assess the association between genotype, phenotype and Prakriti in individuals on phenytoin monotherapy
Keywords: Pharmacogenomics; Ayurveda; Epilepsy; Therapeutic drug monitoring; CYP2C9; CYP2C19;
Pharmacokinetics of diclofenac in healthy controls with wild-type phenotype for CYP2C9 shows metabolism variability
Keywords: Pharmacogenomic; Diclofenac; CYP2C9; Cytochrome p450; Farmacogenómica; Diclofenaco; CYP2C9; Citocromo p450;
Function of 38 variants CYP2C9 polymorphism on ketamine metabolism in vitro
Keywords: Ketamine; CYP2C9; Gene polymorphism; Metabolism; Intrinsic clearance;
CYP2C9 and VKORC1 in therapeutic dosing and safety of acenocoumarol treatment: implication for clinical practice in Hungary
Keywords: AC; acenocoumarol; VKA; vitamin K antagonist; NOACs; novel oral anticoagulants; OEP; Hungarian acronym, National Health Insurance Fund of Hungary; INR; International Normalized Ratio; CYP2C9; Cytochrome P450 2C9; VKORC1; Vitamin K Epoxide Reductase Comple
Interaction of quercetin and its metabolites with warfarin: Displacement of warfarin from serum albumin and inhibition of CYP2C9 enzyme
Keywords: Warfarin; Quercetin metabolites; Human serum albumin; Food-drug interaction; CYP2C9;
CYP2C9 Genotypes Modify Benzodiazepine-Related Fall Risk: Original Results From Three Studies With Meta-Analysis
Keywords: Benzodiazepines; falls; CYP2C9; pharmacogenetics; meta-analyses;
Mild hypothermia decreases the total clearance of glibenclamide after low dose administration in rats
Keywords: Glibenclamide; Mild hypothermia; Pharmacokinetics; CYP2C9;
In vitro metabolism of phenytoin in 36 CYP2C9 variants found in the Chinese population
Keywords: Phenytoin; CYP2C9; Allelic variant; Chinese population; Catalytic activity; In vitro
Evaluation of 16 genotype-guided Warfarin Dosing Algorithms in 310 Korean Patients Receiving Warfarin Treatment: Poor Prediction Performance in VKORC1 1173C Carriers
Keywords: CYP2C9; genotype-guided algorithm; VKORC1; warfarin;
Impact of CYP2C9, VKORC1 and CYP4F2 genetic polymorphisms on maintenance warfarin dosage in Han-Chinese patients: A systematic review and meta-analysis
Keywords: INR; International Normalized Ratio; CYP2C9; Cytochrome P450 Complex Subunit 2C9; CYP4F2; Cytochrome P450 Complex Subunit 4F2; VKORC1; Vitamin K Epoxide Reductase Complex Subunit 1; SNPs; Single Nucleotide Polymorphisms; MDWD; Mean Daily Warfarin Dose; CI
Comparison of rivaroxaban mono-therapy and standard-therapy adjusted by CYP2C9 and VKORC1 genotypes in symptomatic pulmonary embolism
Keywords: Pulmonary embolism; Rivaroxaban; CYP2C9; VKORC1; Deep venous thrombosis;
Association of CYP2C8, CYP2C9 and CYP2J2 gene polymorphisms with myocardial infarction in South Indian population
Keywords: CYP2C8; CYP2C9; CYP2J2; Myocardial infarction; Indian
Genetic polymorphism analysis of the drug-metabolizing enzyme CYP2C9 in a Chinese Tibetan population
Keywords: CYP; Cytochrome P450; LD; Linkage disequilibrium; SNP; single nucleotide polymorphism; nsSNPs; non-synonymous SNPs; MAF; minor allele frequencies; UTR; untranslated region; Genetic polymorphism; CYP2C9; Tibetan populations; Ethnic groups;
Investigation of a recently detected THCCOOH isomer: Post mortem findings and comparison with Î8-THCCOOH
Keywords: Cannabinoids; THCCOOH isomer; Drug testing; In-vitro metabolism; CYP2C9;
Plasma vitamin K concentrations depend on CYP4F2 polymorphism and influence on anticoagulation in Japanese patients with warfarin therapy
Keywords: Warfarin; Vitamin K1; Menaquinone-4; CYP4F2; VKORC1; CYP2C9;
Genotype frequencies of VKORC1 and CYP2C9 in Native and Mestizo populations from Mexico, potential impact for coumarin dosing
Keywords: CYP2C9, cytochrome P-450, family 2, subfamily C9; VKORC1, vitamin K oxidoreductase complex 1Mexican populations; CYP2C9; VKORC1
The influence of VKORC1 gene polymorphism on warfarin maintenance dosage in pediatric patients: A systematic review and meta-analysis
Keywords: Warfarin; Pediatric patients; VKORC1; Gene polymorphisms; Systematic review; Meta-analysis; CI; confidence interval; SD; standard DEVIATION; SNPs; Single nucleotide polymorphisms; CYP2C9; cytochrome P450 complex subunit 2C9; VKORC1; vitamin K epoxide redu
Modulating effect of synthetic statins against damage induced by doxorubicin in somatic cells of Drosophila melanogaster
Keywords: Atorvastatin; Rosuvastatin; Modulatory effect; Smart; Drosophila melanogaster; BH; balancer heterozygote descendants; CYP; cytochrome P450; CYP2C9; cytochrome P450 2C9; CYP 2C19; cytochrome P450 2C19; DXR; doxorubicin; eNOS; endothelial nitric oxide synth
Prevalence of genetic polymorphisms of CYP2C9 and VKORC1 — Implications for warfarin management and outcome in Croatian patients with acute stroke
Keywords: Stroke; Warfarin; Genetic polymorphism; CYP2C9; VKORC1
Association of polymorphism in cytochrome P450 2C9 with susceptibility to head and neck cancer and treatment outcome
Keywords: CYP2C9; PMs; HNSCC; Radio-chemotherapy; Treatment response
VKORC1 and CYP2C9 genotype distribution in Asian countries
Keywords: VKORC1; CYP2C9; Asia; Warfarin;
Structural and energetic analysis to provide insight residues of CYP2C9, 2C11 and 2E1 involved in valproic acid dehydrogenation selectivity
Keywords: Drug metabolism; CYP450 enzymes; Molecular dynamics simulations; Molecular mechanics generalized born surface area; CYP; cytochrome P-450; CYP2C9; cytochrome P-450 C9; CYP2C11; cytochrome P-450 C11; CYP2E1; cytochrome P-450 E1; MD; molecular dynamics; MM-
Med25 is required for estrogen receptor alpha (ERα)-mediated regulation of human CYP2C9 expression
Keywords: CYP; cytochrome P450; Med; Mediator; CAR; constitutive androstane receptor; PXR; pregnane X receptor; GR; glucocorticoid receptor; HNF4α; hepatic nuclear factor 4α; ERα/β; estrogen receptor α/β; E2; 17β-estradiol; RE; responsive element; ERE; estro
Resequencing of VKORC1, CYP2C9 and CYP4F2 genes in Italian patients requiring extreme low and high warfarin doses
Keywords: Warfarin; Pharmacogenetics; Polymorphism; VKORC1; CYP2C9; CYP4F2;
CYP2C9 genotype and association with bone mineral density: A pilot study
Keywords: BMD; bone mineral density; SNP; single nucleotide polymorphism; CYP2C9; cytochrome P450 2C9; DEXA; dual-energy X-ray absorptiometry; BMI; body mass index; Osteoporosis; CYP2C9 mutation; Oral anticoagulant treatment; Glucocorticoid synthesis;
The role of CYP2C9 polymorphisms in phenytoin-related cerebellar atrophy
Keywords: Phenytoin; Cerebellar; CYP2C9; Atrophy;
Differential impact of cytochrome 2C9 allelic variants on clopidogrel-mediated platelet inhibition determined by five different platelet function tests
Keywords: Clopidogrel; CYP2C9; Platelet function testing;
Allele frequency distribution of CYP2C9*2 and CYP2C9*3 polymorphisms in six Mexican populations
Keywords: CEPH-HGDP; Centre d'Etude du Polymorphisme Humain-Human Genome Diversity Project; CYP; cytochrome P-450; CYP2C9; cytochrome P-450 CYP2C9 gene; CYP2C9*1; allele 1 of the CYP2C9 gene; CYP2C9*2; allele 2 of the CYP2C9 gene; CYP2C9*3; allele 3 of the CYP2C9 g
Role of CYP2C9 polymorphism in phenytoin-related metabolic abnormalities and subclinical atherosclerosis in young adult epileptic patients
Keywords: CYP2C9; Lipid profile; Glucose homeostasis; Phenytoin; Epileptic patients; Thailand;
Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties
Keywords: Nicotinamide phosphoribosyltransferase; NAMPT; X-ray crystal structure; Cytochrome P450; CYP2C9;
The impact of the CYP2C9 and VKORC1 polymorphisms on acenocoumarol dose requirements in a Romanian population
Keywords: Acenocoumarol; Romanian population; Genetic variability; CYP2C9; VKORC1