Keywords: Brain aging; Oxidative stress; MDA; NKT; Regional vulnerability; COX-2; Neuroinflammation; CYP2J2; Neuroprotection;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Increased epoxyeicosatrienoic acids may be part of a protective mechanism in human ulcerative colitis, with increased CYP2J2 and reduced soluble epoxide hydrolase expression
Keywords: Epoxyeicosatrienoic acids; CYP2J2; Soluble epoxide hydrolase; Human ulcerative colitis;
Molecular cloning and characterization of the novel CYP2J2 in dromedary camels (Camelus dromedarius)
Keywords: Camel; CYP2J2; Cloning; Sequencing; Bioinformatics; Liver; Heart; Kidney;
Inhibitory Effects of Danshen components on CYP2C8 and CYP2J2
Keywords: Cytochrome P450; Inhibitory effects; Danshen; CYP2C8; CYP2J2; Herb-drug interactions; AA; arachidonic acid; CA; caffeic acid; Cry; cryptotanshinone; CYPs; Cytochrome P450 enzymes; DSS; danshensu; DI; dihydrotanshinone I; EETs; epoxyeicosatrienoic acids; F
Endothelium-specific CYP2J2 overexpression improves cardiac dysfunction by promoting angiogenesis via Jagged1/Notch1 signaling
Keywords: CYP2J2; Angiogenesis; Myocardial infarction; Heart failure; Notch1;
Gene- gene interaction between CYP2J2 and PPAR -γ gene on late-onset Alzheimer's disease in the eastern Chinese Han population
Keywords: PPAR -γ; CYP2J2; SNP; Interaction; Haplotype;
Identification of acetylshikonin as the novel CYP2J2 inhibitor with anti-cancer activity in HepG2 cells
Keywords: Acetylshikonin; CYP2J2; Inhibition; Anti-cancer; HLMs; human liver microsomes; HCC; Hepatocellular carcinoma; DMSO; dimethyl sulfoxide; G6P; glucose-6-phosphate; G6PDH; G6P dehydrogenase; NADP+; β-nicotinamide dinucleotide phosphate; EETs; Epoxyeicosatri
Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo
Keywords: EET; epoxyeicosatrienoic acid; AA; Arachidonic acid; PUFA; polyunsaturated fatty acid; UPLC-MS/MS; ultra-performance liquid chromatography tandem mass spectrometry; ROS; reactive oxygen species; NF- ĸB; nuclear factor -ĸB; RBC; red blood cell; t-AUCB; 4
Activation of ALDH1A1 in MDA-MB-468 breast cancer cells that over-express CYP2J2 protects against paclitaxel-dependent cell death mediated by reactive oxygen species
Keywords: Cytochrome P450 2J2; Breast cancer drug resistance; Reactive oxygen species; Aldehyde dehydrogenase 1A1; 14,15-EET; Cell survival; ALDH1A1; aldehyde dehydrogenase 1A1; CYP2J2; cytochrome P450 2J2; DCFDA; 2â²,7â²-dichlorofluorescein diacetate; DMEM; Dulb
Effects of dronedarone, amiodarone and their active metabolites on sequential metabolism of arachidonic acid to epoxyeicosatrienoic and dihydroxyeicosatrienoic acids
Keywords: AUDA; 212-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid; 4-HBP; 4-hydroxybenzophenone; ACN; acetonitrile; CLother(AA); aggregate clearance of other pathways of AA; CLother(EET); aggregate clearance of other pathways of EET; AA; arac
Ophiopogonin D and EETs ameliorate Ang II-induced inflammatory responses via activating PPARα in HUVECs
Keywords: Ophiopogonin D; CYP2J2; PPARα; Angiotensin II; HUVECs;
Association of CYP2C8, CYP2C9 and CYP2J2 gene polymorphisms with myocardial infarction in South Indian population
Keywords: CYP2C8; CYP2C9; CYP2J2; Myocardial infarction; Indian
CYP epoxygenase 2J2 prevents cardiac fibrosis by suppression of transmission of pro-inflammation from cardiomyocytes to macrophages
Keywords: CYP2J2; cytochrome P450 2J2 epoxygenase; EET; epoxyeicosatrienoic acids; Iso; isoprenaline; Ang II; angiotensin II; NF-κB; nuclear factor kappa-light-chain-enhancer of activated B cells; TGF-β1; transforming growth factor-beta 1; α-SMA; alpha smooth mu
Incorporation of charged residues in the CYP2J2 F-G loop disrupts CYP2J2-lipid bilayer interactions
Keywords: CYP; cytochrome P450; ER; endoplasmic reticulum; ND; nanodisc; PYR; pyrene; PYR-PC; pyrene phosphatidylcholine; MD; molecular dynamics; HMMM; highly mobile membrane mimetic; POPC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; POPS; 1-hexadecanoyl-2-(9
Potential of decursin to inhibit the human cytochrome P450 2J2 isoform
Keywords: CYP2J2; Cytotoxicity; Decursin; Drug interactions; Human liver microsomes;
Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo
Keywords: CYP2J2; CYP2D6; CYP3A4; Time dependent inhibition; Ritonavir; In vivo; SimcypAUC, area under the plasma concentration–time curve; CYP, cytochrome P450 monooxygenase; EM, extensive metabolizer; IM, intermediate metabolizer; HLM, human liver microsomes; PM,
A novel polymorphism of the CYP2J2 gene is associated with coronary artery disease in Uygur population in China
Keywords: CYP2J2; Single nucleotide polymorphism; Coronary artery disease; Case-control study;
Presystemic Metabolism of AZ'0908, A Novel mPGES-1 Inhibitor: An In Vitro and In Vivo Cross-Species Comparison
Keywords: ABC transporters; bioavailability; first-pass metabolism; intestinal metabolism; interspecies correlation; intestinal loss; CYP2J2; pharmacokinetics;
Dual modulation of cyclooxygenase and CYP epoxygenase metabolism and acute vascular inflammation in mice
Keywords: CYP2J2; Soluble epoxide hydrolase; Cyclooxygenase; Vascular inflammation; Epoxyeicosatrienoic acid; Prostaglandin
Association of eNOS (E298D) and CYP2J2 (−50 G/T) gene polymorphisms with hypertension among Egyptian cases
Keywords: eNOS; CYP2J2; Polymorphism; Hypertension
A new cytochrome P450 belonging to the 107L subfamily is responsible for the efficient hydroxylation of the drug terfenadine by Streptomyces platensis
Keywords: Xenobiotics; Oxidation; Antihistamine; Actinomycete; Biotransformation; Ferredoxin reductase; CYP107L; P450terf; CYP2J2; PikC; Macrolides
Expression of the cytochrome P450 epoxygenase CYP2J2 in human monocytic leukocytes
Keywords: AA, arachidonic acid; ApoE, apolipoprotein E; CYP, cytochrome P450; EET, epoxyeicosatetraenoic acid; FBS, fetal bovine serum; MMP, matrix metalloproteinase; PBMC, peripheral blood mononuclear cell.Cytochrome P450 epoxygenase; CYP2J2; Epoxyeicosatrienoic a
CYP2J2*7 single nucleotide polymorphism in a Chinese population
Keywords: Cytochrome P450; CYP2J2; Genetic polymorphism; Chinese
Characterization of rat and human CYP2J enzymes as Vitamin D 25-hydroxylases
Keywords: vitamin D3; vitamin D2; 25-Hydroxylase; CYP2J2; CYP2J325(OH)D3, 25-hydroxyvitaimin D3; 1,25(OH)2D3, 1,25-dihydroxyvitamin D3; 1α(OH)D3, 1α-hydroxyvitamin D3; CYP, cytochrome P450; HPLC, high performance liquid chromatography; PCR, polymerase chain reactio