Keywords: signal transduction; cys-loop receptors; intracellular domains; protein structure; proteomics; evolution
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Functional properties and mechanism of action of PPTQ, an allosteric agonist and low nanomolar positive allosteric modulator at GABAA receptors
Keywords: Ago-PAM; allosteric agonist and positive allosteric modulator; C/R; concentration-response; ECD; extracellular domain; FMP; FLIPR Membrane Potential Blue; GABA; γ-Aminobutyric acid; GABAAR; GABAA receptor; methaqualone; 2-methyl-3-(o-tolyl)-quinazolin-4(
Progress in the discovery of small molecule modulators of the Cys-loop superfamily receptors
Keywords: Cys-loop receptors; Ligand-gated ion channels; Nicotinic acetylcholine receptors; Serotonin type 3 receptors; γ-Aminobutyric acid receptor; Glycine receptors;
Exploring the positive allosteric modulation of human α7 nicotinic receptors from a single-channel perspective
Keywords: Cys-loop receptors; Nicotinic receptors; Patch-clamp; Single-channel recordings; Positive allosteric modulators; nAChR; nicotinic acetylcholine receptor; ACh; acetylcholine; 5-HT3A; serotonin type 3A receptor; PAM; positive allosteric modulator; PAM-2; 3-
Atomistic insights into human Cys-loop receptors by solution NMR
Keywords: Cys-loop receptors; Channel structures; nAChRs; Glycine receptoers; NMR; Anesthetic binding
Subunit interfaces contribute differently to activation and allosteric modulation of neuronal nicotinic acetylcholine receptors
Keywords: Nicotinic acetylcholine receptors; Allosteric regulation; Mutagenesis site specific; Cysteine-mediating cross-linking; Interface; Oocyte; Cys-loop receptors; nAChR; nicotinic acetylcholine receptor; Mor; morantel; Oxa; oxantel; OR2; oocyte Ringer's; DTT;
Benzodiazepine modulation of homomeric GABAAÏ1 receptors: Differential effects of diazepam and 4â²-chlorodiazepam
Keywords: GABA; γ-aminobutyric acid; GABAA receptors; GABAARs; BDZs; benzodiazepines; TPMPA; (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid; TACA; trans-aminocrotonic acid; CACA; cis-aminocrotonic acid; CNS; central nervous system; TEVC; two electrode volta
Constrained geometric simulation of the nicotinic acetylcholine receptor
Keywords: Nicotinic acetylcholine receptor; froda; first; Membrane protein; Cys-loop receptors; Ligand-gated ion channels
New insights into the structural bases of activation of Cys-loop receptors
Keywords: Cys-loop receptors; Gating; Nicotinic receptor; 5-HT3 receptor; Ion channel; Synaptic transmission
Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors
Keywords: Nicotinic acetylcholine receptors (nAChR); Acetylcholine binding protein (AChBP); Electrophysiology; In silico screening; Virtual screening; Docking; Crystallization; Ligand-gated ion channels (LGICs); Cys-loop receptors
Tricyclic antidepressants inhibit homomeric Cys-loop receptors by acting at different conformational states
Keywords: Nicotinic receptor; Cys-loop receptors; Tricyclic antidepressant; Noncompetitive inhibitors