Keywords: Cyt C، Cytochrome C; Peroxidase activity; Resonance Raman; Circular dichroism; Ligand binding kinetics; Site directed mutagenesis; ApoptosisApaf 1, apoptotic protease-activating factor 1; Cyt c, cytochrome c; CL, cardiolipin; CD, circular dichroism; CT, charge transfer; CT1,
مقالات ISI Cyt C، Cytochrome C (ترجمه نشده)
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Structural and functional characterization of phosphomimetic mutants of cytochrome c at threonine 28 and serine 47
Keywords: Cyt C، Cytochrome C; Ac-DEVD-AMC, acetyl-Asp-Glu-Val-Asp-7-amino-4-methylcoumarin; Apaf-1, apoptosis protease activation factor-1; Cyt bc1, cytochrome bc1 complex; Cyt c, cytochrome c; Cyt c1, cytochrome c1; COX, cytochrome c oxidase; CD, circular dichroism; CHAPS, 3-[(3-chol
Deoxynivalenol induces apoptosis in PC12 cells via the mitochondrial pathway
Keywords: Cyt C، Cytochrome C; DON, deoxynivalenol; Cyt C, cytochrome C; AIF, apoptosis inducing factor; DMEM, dulbecco’s modified eagle’s medium; FBS, fetal bovine serum; CCK-8, cell counting kit-8; OD, optical density; BSA, bovine serum albumin; PI, propidium iodide; LDH, lactate deh
SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway
Keywords: Cyt C، Cytochrome C; SKF-96365; Autophagy; Apoptosis; Colorectal cancer; CaMKII△ψm, membrane potential; 3-MA, 3-methyladenine; Ca2+, calcium ion; CaMKIIγ, calmodulin-dependent kinase IIγ; COX-2, cyclooxygenase-2; CQ, chloroquine; CRC, colorectal cancer; cyt c, cytochrome c; E
Characterization of molecular mechanism of neuroglobin binding to cytochrome c: A surface plasmon resonance and isothermal titration calorimetry study
Keywords: Cyt C، Cytochrome C; Cyt c, cytochrome c; EIS, electrochemical impedance spectroscopy; hNgb, human neuroglobin; ITC, isothermal titration calorimetry; Mb, myoglobin; SAM, self-assembled monolayer; SPR, surface plasmon resonanceCD loop; SPR sensor; Electrochemical impedance sp
Peroxidative permeabilization of liposomes induced by cytochrome c/cardiolipin complex
Keywords: Cyt C، Cytochrome C; cyt c, cytochrome c; CF, 5(6)-carboxyfluorescein; SRB, sulforhodamine B; PC, soybean phosphatidylcholine; CL, bovine heart cardiolipin; TMCL, tetramyristoyl-cardiolipin; DPhPC, diphytanoylphosphatidylcholine; BHT, butylated hydroxytoluene; EDTA, ethylened
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells
Keywords: Cyt C، Cytochrome C; TCBQ; Apoptosis; Neurotoxicity; Caspase; ROS; BidBid, BH3-interacting domain death agonist; Cyt c, cytochrome c; DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride; DCFH-DA, 2′,7′-dichlorodihydrofluorescein diacetate; DISC, death-inducing signaling compl
III-10, a newly synthesized flavonoid, induces cell apoptosis with the involvement of reactive oxygen species-mitochondria pathway in human hepatocellular carcinoma cells
Keywords: Cyt C، Cytochrome C; AIF, apoptosis-inducing factor; Cyt C, cytochrome c; ERK, extracellular regulated protein kinase; GSH, glutathione; JNK, c-Jun N-terminal kinase; MAPK, mitogen-activated protein kinases; MMP, mitochondrial membrane potential; NAC, N-acetyl-cysteineApoptos
Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport
Keywords: Cyt C، Cytochrome C; SM, smac mimetic; IAP, inhibitor of apoptosis protein; BIR, baculoviral IAP repeat; PCD, programmed cell death; TNF, tumor necrosis factor; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; Cyt c, cytochrome c; Smac/DIABLO, second mitochondr
Analysis of opa1 isoforms expression and apoptosis regulation in autosomal dominant optic atrophy (ADOA) patients with mutations in the opa1 gene
Keywords: Cyt C، Cytochrome C; AU, arbitrary units; ADOA, autosomal dominant optic atrophy; cyt c, cytochrome c; dRib, 2-deoxy-d-ribose; GED, GTPase effector domain; IMM, inner mitochondrial membrane; ΔΨm, mitochondrial membrane potential; MTS, mitochondrial targeting signal; OMM, oute
A tryptophanol-derived oxazolopiperidone lactam is cytotoxic against tumors via inhibition of p53 interaction with murine double minute proteins
Keywords: Cyt C، Cytochrome C; Δψm, mitochondrial membrane potential; CFU, colony-forming units; co-IP, co-immunoprecipitation; cyt c, cytochrome c; DMSO, dimethyl sulfoxide; FCCP, p-triflouromethoxyphenylhydrazone; IgG, immunoglobulin G; PI, propidium iodide; MDM2, murine double minut
Association of low GLP-1 with oxidative stress is related to cardiac disease and outcome in patients with type 2 diabetes mellitus: A pilot study
Keywords: Cyt C، Cytochrome C; ∆Ψm, mitochondrial membrane potential; 8-OH-dG, 8-hydroxy-2′-deoxyguanosine; ATPs (V), ATP synthase or Complex V; Cr, creatine; CR, cardiac remodeling; CVE, cardiovascular events; Cyt c, cytochrome c; DPP4, dipeptidyl peptidase-4; GLP-1, glucagon-like pep
Polyethylenimine architecture-dependent metabolic imprints and perturbation of cellular redox homeostasis
Keywords: Cyt C، Cytochrome C; AMPK, AMP kinase; Anti-A, antimycin A; Asc, ascorbate; 2-DG, 2-deoxy-d-glucose; NAC, N-acetyl-cysteine; NaN3, sodium azide; CI, complex I; CII, complex II; CIII, complex III; CIV, complex IV; CS, citrate synthase; cyt c, cytochrome c; DMEM, Dulbecco's Mod
α7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways
Keywords: Cyt C، Cytochrome C; ACh, acetylcholine; nAChR, nicotinic acetylcholine receptor; cyt c, cytochrome c; MLA, methyllicaconitine; MPTP, mitochondria permeability transition pore; ROS, reactive oxygen species; CaMKII, calcium-calmodulin-dependent kinase; PKC, protein kinase C; P
Structural transformations of cytochrome c upon interaction with cardiolipin
Keywords: Cyt C، Cytochrome C; Apoptosis; Peroxidase; Protein folding; HemeATP, adenosine triphosphate; CD, circular dichroism; CT, charge transfer; CL, cardiolipin; cyt c, cytochrome c; DOPG, dioleoyl phosphatidylglycerol; EPR, electron paramagnetic resonance; FRET, fluorescence reson
G2019S LRRK2 mutant fibroblasts from Parkinson’s disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy
Keywords: Cyt C، Cytochrome C; AVs, autophagic vacuoles; Baf A1, bafilomycin A1; C, control; Cyt c, cytochrome c; DiOC6(3), 3-dihexyloxacarbocyanine iodide; FITC, fluorescein isothiocyanate; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GS, G2019S; HE, hydroethidine; Ho, Hoechst 333
LL-202, a newly synthesized flavonoid, inhibits tumor growth via inducing G2/M phase arrest and cell apoptosis in MCF-7 human breast cancer cells in vitro and in vivo
Keywords: Cyt C، Cytochrome C; BCA, bicinchoninic acid; CAK, CDK-activating kinase; Cyt c, cytochrome c; CDKs, cyclin-dependent kinases; DAPI, 4′-6-diamidino-2-phenylindole; DCFH/DA, 2′,7′-dichlorodihydrofluorescein diacetate; DMSO, dimethylsulfoxide; FBS, Fetal bovine serum; MMP, mito
Neuroprotective effects of gallic acid against hypoxia/reoxygenation-induced mitochondrial dysfunctions in vitro and cerebral ischemia/reperfusion injury in vivo
Keywords: Cyt C، Cytochrome C; ANT, adenine nucleotide translocator; BCA, bicinchoninic acid; CsA, cyclosporin A; CypD, Cyclophilin D; Cyt C, Cytochrome C; DAPI, 4׳, 6-diamidino-2-phenylindole; DCF-DA, dichlorofluorescin diacetate; DMEM, dulbecco’s modified Eagle׳s medium; DMSO, dimeth
Human-Gyrovirus-Apoptin Triggers Mitochondrial Death Pathway—Nur77 is Required for Apoptosis Triggering
Keywords: Cyt C، Cytochrome C; 7AAD, 7-amino-actinomycin D; AIF, Apoptosis inducing factor; BCL-XL, B-cell lymphoma extra-large; CAV-Apoptin, Chicken anemia virus apoptin; cyt c, cytochrome c; DISC, Death-inducing signal complex; FADD, Fas-associated death domain; HGV-Apoptin, Human gy
Thickness and morphology of polyelectrolyte coatings on silica surfaces before and after protein exposure studied by atomic force microscopy
Keywords: Cyt C، Cytochrome C; Atomic force microscopy; Dextran sulfate; Noncovalent polyelectrolyte coatings; Polybrene; Poly(vinylsulfonic acid); Protein adsorptionAFM, atomic force microscopy; cyt c, cytochrome c; PB, polybrene; DS, dextran sulfate; PVS, poly (vinylsulfonic acid); C
Comparative toxicity and apoptosis induced by diorganotins in rat pheochromocytoma (PC12) cells
Keywords: Cyt C، Cytochrome C; AIF, apoptosis-inducing factor; Apaf-1, apoptotic protease activation factor 1; AO, acridine orange; Cyt c, cytochrome c; DCF, dichlorofluorescein; DCFH, dichlorofluorescein; DCFH-DA, 2′,7′-dichlorofluorescein-diacetate; DMEM, Dulbecco’s modified Eagle’s
Equine platelets inhibit E. coli growth and can be activated by bacterial lipopolysaccharide and lipoteichoic acid although superoxide anion production does not occur and platelet activation is not associated with enhanced production by neutrophils
Keywords: Cyt C، Cytochrome C; cyt C, cytochrome C; FMLP, formyl methionyl-leucyl-phenylalanine; FPR, formyl peptide receptors; HBSS, Hank's balanced salt solution; HEPES, N-[2-hydroxyethyl]piperazine-N′-[2-ethanesulphonic acid]; LPRP, leucocyte-platelet rich plasma; LTA, lipoteichoic
High resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system
Keywords: Cyt C، Cytochrome C; Anti-A, antimycin A; Asc, ascorbate; NaN3, sodium azide; CCCP, carbonyl cyanide m-chlorophenylhydrazone; CI, complex I; CII, complex II; CIII, complex III; CIV, complex IV; cyt c, cytochrome c; DIC, differential interference contrast; ETS, electron transp
Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate
Keywords: Cyt C، Cytochrome C; BSA, bovine serum albumin; cdk5, cyclin-dependent kinase 5; cGMP, cyclic guanosine monophosphate; Cyt c, cytochrome c; DG, dentate gyrus; LDH, lactate dehydrogenase; MCAo, middle cerebral artery occlusion; MDL28170, carbobenzoxy-valinyl-phenyl-alaninal; M
What is behind the non-antibiotic properties of minocycline?
Keywords: Cyt C، Cytochrome C; AIF, apoptosis-inducing factor; Apaf-1, apoptotic protease activator factor-1; APCs, antigen presenting cells; CNS, central nervous system; COX, cyclooxygenase; Cyt c, cytochrome c; ERK, extracellular signal-regulated kinase; FDA, US Food and Drug Adminis
Overexpression of Shp-2 attenuates apoptosis in neonatal rat cardiac myocytes through the ERK pathway
Keywords: Cyt C، Cytochrome C; Shp-2, Src homology 2 domain-containing protein tyrosine phosphatase 2; Cyt C, cytochrome C; PTP, protein tyrosine phosphatase; ERK, extracellular signal-regulated protein kinase; MAPK, mitogen-activated protein kinase; EGCG, epigallocatechin-3-gallateShp
Signaling of endothelial cytoprotection in transplantation
Keywords: Cyt C، Cytochrome C; AP-1, activator protein-1; APC, activated protein C; Bcl-2, B cell lymphoma-2 protein; Bad, Bcl-2 antagonist of cell death; Bcl-xl, Bcl-extra long; CO, carbon monoxide; COX, cyclooxygenase; Cyt c, cytochrome c; Dll, Delta-like; EC, endothelial cell; eNOS,
Photosynthetic electron flow to oxygen and diffusion of hydrogen peroxide through the chloroplast envelope via aquaporins
Keywords: Cyt C، Cytochrome C; Amplex Red, 10-acetyl-3,7-dihydroxyphenoxazine; AZA, acetazolamide; CA, carbonic anhydrase; CHA, cyclic hydroxylamine; Chl, chlorophyll; cyt c, cytochrome c; Gr D, gramicidin D; MV, methyl viologen; POBN, α-(4-pyridyl-1-oxide)-N-tert-butylnitron; PQH2, pl
The effect of lysozyme amyloid fibrils on cytochrome c–lipid interactions
Keywords: Cyt C، Cytochrome C; Cyt c, cytochrome c; CL, cardiolipin; PC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; PG, 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-rac-glycerol; PS, 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-rac-phosphatidylserine; AV-PC, 1-acyl-2-[12-(9-anthryl)-1
Neuroglobin of seals and whales: Evidence for a divergent role in the diving brain
Keywords: Cyt C، Cytochrome C; Cyt c, cytochrome c; GFAP, glial fibrillary acidic protein; Hb, hemoglobin; Mb, myoglobin; Ngb, neuroglobin; PBS, phosphate-buffered saline; ROS, reactive oxygen speciesastrocytes; cetacea; hypoxia; lactate shuttle; oxygen; Pinnipedia
(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death
Keywords: Cyt C، Cytochrome C; AIF, apoptosis-inducing factor; cyt c, cytochrome c; Hsp70, heat shock protein 70; I/R, ischemia/reperfusion; MCAO, middle cerebral artery occlusion; NBP, 3-n-butylphthalide; NO, nitric oxide; OGD, Oxygen–glucose deprivation; ROS, reactive oxygen species;
An investigation into a cardiolipin acyl chain insertion site in cytochrome c
Keywords: Cyt C، Cytochrome C; cyt c, cytochrome c; CL, cardiolipin; ET, electron transfer; WT, wild-type; Amp, ampicillan; CD, circular dichroism; GuHCl, guanidine hydrochloride; CAPS, 3-(cyclohexylamino)-1-propanesulfonic acid; Tris, tris(hydroxymethyl)aminomethane; Em, midpoint redo
Reactive oxygen species induced by p66Shc longevity protein mediate nongenomic androgen action via tyrosine phosphorylation signaling to enhance tumorigenicity of prostate cancer cells
Keywords: Cyt C، Cytochrome C; Ab, antibody; AcP, acid phosphatase; AI, androgen independent; AR, androgen receptor; AS, androgen sensitive; cPAcP, cellular prostatic acid phosphatase; Cyt c, cytochrome c; DCF-DA, dichlorofluorescein diacetate; DHT, 5α-dihydrotestosterone; EGF, epiderm
LFG-500, a newly synthesized flavonoid, induced a reactive oxygen species-mitochondria-mediated apoptosis in hepatocarcinoma cells
Keywords: Cyt C، Cytochrome C; Flavonoid; Apoptosis; Mitochondria; Reactive oxygen speciesDAPI, diamidino-phenyl-indole; ROS, reactive oxygen species; Cyt c, cytochrome c; AIF, apoptotic inducing factor; MMP, mitochondrial membrane potential
Imatinib mesylate induction of ROS-dependent apoptosis in melanoma B16F0 cells
Keywords: Cyt C، Cytochrome C; Bcl-2, B-cell lymphoma 2; Cyt c, cytochrome c; DCFH-DA, 2′,7′-dichlorofluorescein diacetate; DMSO, dimethyl sulfoxide; DPI, dipheylene iodide; ERK, extracellular regulated kinase; JNK, c-Jun-N-terminal protein kinase; MAPK, mitogen-activated protein kinas
Modulation of Bax mitochondrial insertion and induced cell death in yeast by mammalian protein kinase Cα
Keywords: Cyt C، Cytochrome C; PKCα, protein kinase Cα; ROS, reactive oxygen species; Cyt c, cytochrome c; PI, propidium iodide; H2DCFDA, dichlorodihydrofluorescein diacetateApoptosis; Bax; Protein kinase C; Yeast mitochondria
Modulation of Bax/Bcl-2 and caspases by probiotics during acetaminophen induced apoptosis in primary hepatocytes
Keywords: Cyt C، Cytochrome C; AIF, apoptosis inducing factor; ATP, adenosine triphosphate; APAP, acetaminophen; cyt c, cytochrome c; DCF, dichlorofluorescein; DCFH–DA, dichlorofluorescein–diacetate; EDTA, ethylenediamine tetraacetic acid; EGTA, ethylene glycol tetra acetic acid; ElSN,
AICAR inhibits cancer cell growth and triggers cell-type distinct effects on OXPHOS biogenesis, oxidative stress and Akt activation
Keywords: Cyt C، Cytochrome C; ADP, adenosine diphosphate; AICAR, 5-amino-4-imidazolecarboxamide ribonucleoside; ANT, adenine nucleoide translocator; ATP, adenosine triphosphate; COX, cytochrome c oxidase; Cyt c, cytochrome c; CoQ, coenzyme Q; OXPHOS, oxidative phosphorylation; RCR, re
The medium reorganization energy for the charge transfer reactions in proteins
Keywords: Cyt C، Cytochrome C; BRC, bacterial reaction center of photosynthesis; CcO, cytochrome c oxidase; cyt c, cytochrome c; ESP, electrostatic potential (charges); MADH, methylamine dehydrogenase; MO, molecular orbital; pdb, protein data bank; THI, tetrahedral intermediateProtein
A theoretical investigation of the functional role of the axial methionine ligand of the CuA site in cytochrome c oxidase
Keywords: Cyt C، Cytochrome C; CcO, cytochrome c oxidase; MD, Molecular dynamics; QM, Quantum mechanics; MM, Molecular mechanics; Cyt c, cytochrome c; MOE, molecular operating environmentTransition metal binding protein; Redox potential; Electron transfer; Electronic structure; Structu
Yeast acetic acid-induced programmed cell death can occur without cytochrome c release which requires metacaspase YCA1
Keywords: Cyt C، Cytochrome C; AA, acetic acid; PCD, programmed cell death; AA-PCD, acetic acid-induced programmed cell death; wt, wild type; Δyca1, YCA1-lacking; Δcyc1,7, cytochrome c lacking; H2O2, hydrogen peroxide; cyt c, cytochrome c; DCF, dichlorofluorescein diacetate; z-VAD-fmk,
Doxorubicin coupled to penetratin promotes apoptosis in CHO cells by a mechanism involving c-Jun NH2-terminal kinase
Keywords: Cyt C، Cytochrome C; CPP, cell penetrating peptide; Cyt c, cytochrome c; DHE, dihydro-ethidium; DMSO, dimethyl sulfoxide; Dox, doxorubicine; FACS, fluorescence activated cell sorting; FITC, Fluoresceine IsoThioCyanate; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliu
Salt stress induces programmed cell death in Thellungiella halophila suspension-cultured cells
Keywords: Cyt C، Cytochrome C; Cyt c, cytochrome c; DMSO, dimethyl sulfoxide; PCD, programmed cell death; ROS, reactive oxygen speciesAutophagy; Caspase 3-like protease; Programmed cell death; Salt stress; Thellungiella halophila
Prostaglandin A2 activates intrinsic apoptotic pathway by direct interaction with mitochondria in HL-60 cells
Keywords: Cyt C، Cytochrome C; AA, ascorbic acid; BKA, bongkrekic acid; CsA, cyclosporine A; Cyt C, cytochrome c; MAC, mitochondrial apoptosis-induced channel; MIM, mitochondrial inner membrane; MOM, mitochondrial outer membrane; MOMP, mitochondrial outer membrane permeabilization; MPT
Importance of cytochrome c redox state for ceramide-induced apoptosis of human mammary adenocarcinoma cells
Keywords: Cyt C، Cytochrome C; C-2 ceramide, N-Acetyl-D-sphingosine; C-6 ceramide, N-Caproyl-C18-sphingosine; DHC, Dihydroceramide; cyt c, cytochrome c; Δψ, mitochondrial transmembrane potential; cytoxy, oxidized cytochrome c; cytred, reduced cytochrome c; TBARS, thiobarbituric acid re
AMPK-independent down-regulation of cFLIP and sensitization to TRAIL-induced apoptosis by AMPK activators
Keywords: Cyt C، Cytochrome C; cFLIP, cellular FLICE-inhibitory protein; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; TNF, tumor necrosis factor; DISC, death-inducing signalling complex; FADD, Fas-associated death domain; Cyt c, cytochrome c; DD, death domain; DED, d
Time-Dependent Changes in Side-Chain Solvent Accessibility during Cytochrome c Folding Probed by Pulsed Oxidative Labeling and Mass Spectrometry
Keywords: Cyt C، Cytochrome C; ·OH, hydroxyl radical; cyt c, cytochrome c; ESI, electrospray ionization; HDX, hydrogen/deuterium exchange; MS, mass spectrometry; MS/MS, tandem MSfolding intermediate; heme misligation; covalent labeling; heme protein; protein oxidation
Mitochondrial gateways to cancer
Keywords: Cyt C، Cytochrome C; ACL, ATP citrate lyase; AIF, apoptosis inducing factor; AML, acute myeloid leukemia; ANT, adenine nucleotide translocase; BH, Bcl-2 homology domain; CRT, calreticulin; CypD, cyclophilin D; Cyt c, cytochrome c; Δψm, mitochondrial transmembrane potential; D
Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO and protects mouse embryonic cells against irradiation-induced apoptosis
Keywords: Cyt C، Cytochrome C; HVTP, (2-hydroxyamino-vinyl)-triphenyl-phosphonium; CL, cardiolipin; TOCL, 1,1,2,2-tetraoleoyl cardiolipin; PC, phosphatidylcholine; ROS, reactive oxygen species; cyt c, cytochrome c; HPLC, high performance liquid chromatography; NO, nitric oxide radical;
Disulfide and thioether linked cytochrome c-oligoarginine conjugates in HeLa cells
Keywords: Cyt C، Cytochrome C; CPP, cell penetrating peptide; Cyt c, cytochrome c; SPDP, N-succinimidyl 3-(2-pyridyldithio) propionate; SMPB, succimidyl 2-[p-maleimidophenyl]butyrateCytochrome c; Cell penetrating peptides; Oligoarginine; Apoptosis; Intracellular degradation