دانلود مقالات ISI درباره Cytochrome P450 3A + ترجمه فارسی

آیا ارتباطات بالینی متابولیسم مواد مخدر و داروهای گیاهی محدود به آب گریپ فروت و داروهای سینت جان است؟

Is the clinical relevance of drug-food and drug-herb interactions limited to grapefruit juice and Saint-John's Wort?

Keywords: HIV; Human Immunodeficiency Virus; CYP; Cytochrome P450; TKI; tyrosine kinase inhibitor; P-gp; P-glycoprotein; OATP; Organic Anion Transporting Polypeptide; INR; International Normalized Ratio; Drug-food interactions; Clinical practice; Cytochrome P450 3A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

کارکرد منطقی کشت سلولی نسبت به تکنیک های معمول در ارزیابی دارویی نانوذرات

Rationale employment of cell culture versus conventional techniques in pharmaceutical appraisal of nanocarriers

Keywords: P-gp; P-glycoproteins; BEs; bioactive excipients; AP; apical; BL; basolateral; Papp; apparent permeability; CYP3A4; cytochrome P450 3A; HCC; hepatocellular carcinoma; BBB; blood-brain barrier; ER; Estrogen receptor; Cell line; Nanomedicine; Permeability

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

پیشرفت های اخیر در تحویل داروهای ترکیبات اسید نوکلئیک برای درمان سرطان

Recent advances in delivery of drug-nucleic acid combinations for cancer treatment

Keywords: siRNA; small interfering RNA; AON; antisense oligonucleotides; shRNA; small hairpin RNA; pDNA; plasmid DNA; CYP3A; cytochrome P450 3A; MDR; multidrug resistance; MDR1; multidrug resistance protein 1; Pgp; P-glycoprotein; TRAIL; tumor necrosis factor-relat

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

Assessment of induced CYP3A activity in pregnant women using 4β-hydroxycholesterol: Cholesterol ratio as an appropriate metabolic marker

Keywords: Pregnancy; Cytochrome P450 3A; Metabolic markers; 4β-hydroxycholesterol/cholesterol; GC-MS;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of P-glycoprotein and CYP 3A by Coptidis Rhizoma in vivo: Using cyclosporine as a probe substrate in rats

Keywords: Cyclosporine; P-glycoprotein; Cytochrome P450 3A; Herb-drug interactions; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

The time-dependent effects of St John's wort on cytochrome P450, uridine diphosphate-glucuronosyltransferase, glutathione S-transferase, and NAD(P)H-quinone oxidoreductase in mice

Keywords: cytochrome P450 2C; cytochrome P450 3A; Hypericum perforatum; liver; kidney;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-κB signaling pathway in secondary hyperparathyroidism

Keywords: Chronic kidney disease; Cytochrome P450 3A; Cinacalcet; Parathyroid hormone; Secondary hyperparathyroidism;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Determinants of Intestinal Availability for P-glycoprotein Substrate Drugs Estimated by Extensive Simulation With Mathematical Absorption Models

Keywords: drug-drug interaction; P-glycoprotein; physiologically based pharmacokinetic model; modeling and simulation; intestinal absorption; substrate drug; CLh; hepatic clearance; CLr; renal clearance; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; EQ

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewInfluence of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on expression of P-glycoprotein and cytochrome P450 3A in sheep

Keywords: P-gp,MDR1,ABCB1; P-glycoprotein; CYP3A4; cytochrome P450 3A; VDR; vitamin D receptor; PXR; pregnane X receptor; RXR; αretinoid X receptor; BW; body weight; 25-OHD3; 25-hydroxyvitamin D3; 1,25-(OH)2D3; 1,25-dihydroxyvitamin D3; Cholecalciferol; Ruminant;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

An ultra-high performance liquid chromatography-tandem mass spectrometric assay for quantifying 3-ketocholanoic acid: Application to the human liver microsomal CYP3A-dependent lithocholic acid 3-oxidation assay

Keywords: CYP; cytochrome P450; CYP3A; cytochrome P450 3A; DMSO; dimethyl sulfoxide; HPLC-UV; high-performance liquid chromatography-ultraviolet spectroscopy; 3-KCA; 3-ketocholanoic acid; LC-MS/MS; liquid chromatography-tandem mass spectrometry; LCA; lithoc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Cyp3a deficiency enhances androgen receptor activity and cholesterol synthesis in the mouse prostate

Keywords: AR; androgen receptor; ARE; androgen response element; ChIP; chromatin immunoprecipitation; CYP3A; cytochrome P450 3A; Ddt; D-dopachrome tautomerase; Hmgcr; HMG-CoA reductase; Hmgcs1; HMG-CoA synthase 1; HPLC; high-performance liquid chromatography; Ldlr;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Influence of HIV antiretrovirals on methadone N-demethylation and transport

Keywords: Methadone; Hepatocytes; Protease inhibitors; Cytochrome P450 3A; CYP3A; Cytochrome P450 2B6; CYP2B6;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Role of CYP3A in Isoniazid Metabolism In Vivo

Keywords: isoniazid; metabolism; cytochrome P450 3A; hepatotoxicity; mice;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Exposure to DEHP and MEHP from hatching to adulthood causes reproductive dysfunction and endocrine disruption in marine medaka (Oryzias melastigma)

Keywords: arα; androgen receptor α; BSI; brain somatic index; cyp3a; cytochrome P450 3a; cyp11b; cytochrome P450 11b; cyp17a1; cytochrome P450 17α-hydroxylase 1; cyp19; cytochrome P450 19; cyp21a; CYP450 21-α-hydroxylase; DEHP; di-(2-ethylhexyl)-phthalate; DMSO

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn

Keywords: Praeruptorin D; Pregnane X receptor (PXR); Cytochrome P450 3A; Induction; Herb-drug interaction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Concentration-dependent inhibitory effects of baicalin on the metabolism of dextromethorphan, a dual probe of CYP2D and CYP3A, in rats

Keywords: S. baicalensis; Scutellaria baicalensis; CYP; cytochrome P450; CYP2D; cytochrome P450 2D; CYP3A; cytochrome P450 3A; DXM; dextromethorphan; BG; baicalin; RLMs; rat liver microsomes; Km; substrate concentration at half-maximal product formation rate; Ki; i

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Stereoselective excretion and first-pass metabolism of clausenamide enantiomers

Keywords: Clausenamide enantiomers; Excretion; First-pass effect; Metabolism; Cytochrome P450 3A; Stereoselectivity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Enhanced intestinal absorption of etoposide by self-microemulsifying drug delivery systems: Roles of P-glycoprotein and cytochrome P450 3A inhibition

Keywords: Etoposide; Self-microemulsifying drug delivery system; Absorption; P-glycoprotein; Cytochrome P450 3A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

mRNA expression profiles of P450 3A enzymes in the liver and small intestine of the domestic pig

Keywords: Pig; Cytochrome P450 3A; Expression; Liver; Small intestine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Induction of cytochrome P450 3A by Shexiang Baoxin Pill and its main components

Keywords: P450; cytochrome P450; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; TCM; traditional Chinese medicine; SBP; Shexiang Baoxin Pill; MDZ; midazolam; CHD; coronary heart diseases; MUS; muscone; TES; testosterone; GRf; ginsenoside Rf; GRg1; ginseno

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Consumption of a high-fat diet during pregnancy decreases the activity of cytochrome P450 3a in the livers of offspring

Keywords: Cytochrome P450 3a; High-fat diet; Pregnancy; Liver; Offspring

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Post-translational modification of pregnane x receptor

Keywords: PXR; pregnane x receptor; NR; nuclear receptor; PCN; pregnenalone 16α-carbonitrile; Rif; rifampicin; G6Pase; glucose-6-phosphatase; PEPCK; phosphoenolpyruvate carboxykinase; CYP3A; cytochrome P450 3A; CREs; cyclic AMP response elements; PKA; cyclic AMP-d

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer––The Rotterdam Study

Keywords: Cytochrome P450 3A; Polymorphism; Prostate cancer; Steroid hormone levels

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs

Keywords: Cytochrome P450 3A; Ritonavir; Lopinavir

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Nonionic surfactants are strong inhibitors of cytochrome P450 3A biotransformation activity in vitro and in vivo

Keywords: Nonionic surfactants; Cytochrome P450 3A; Midazolam; Pharmacokinetics

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of synthetic polycyclic musks on estrogen receptor, vitellogenin, pregnane X receptor, and cytochrome P450 3A gene expression in the livers of male medaka (Oryzias latipes)

Keywords: Polycyclic musk fragrance; Oryzias latipes; Estrogen receptor α; Vitellogenin; Pregnane X receptor; Cytochrome P450 3A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Decreased Drug Penetration in Inflamed Tissue Related to Changed Mucosal Metabolism in Experimental Colitis

Keywords: colitis; inflammatory bowel disease; cytochrome P450 3A; tissue penetration; drug targeting;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Generation of specific antibodies and their use to characterize sex differences in four rat P450 3A enzymes following vehicle and pregnenolone 16α-carbonitrile treatment

Keywords: CYP3A; Cytochrome P450 3A; P450 3A1; P450 3A2; P450 3A9; P450 3A18; Specific antibody; Quantitative Western blot; Baculovirus expression system; Testosterone metabolism; Pregnenolone 16α-carbonitrile

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles

Keywords: Cytochrome P450 3A; Haplotype; Polymorphism; CYP3A4*1B; Phenotype-genotype associations; Quinine; Interethnic differences;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Chronic ethanol exposure downregulates hepatic expression of pregnane X receptor and P450 3A11 in female ICR mice

Keywords: Ethanol; Endotoxin; Pregnane X receptor; Cytochrome P450 3A; Kupffer cells;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta

Keywords: cDNA; complementary DNA; CYP3A; cytochrome P450 3A; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IL-1; interleukin-1; IL-6; interleukin-6; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; MDR1; multidrug resistance 1; NAC; N-acetylcyste

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه