Re-invigorating the insecticide discovery pipeline for vector control: GPCRs as targets for the identification of next gen insecticides
Keywords: AaDOP, Aedes aegypti dopamine receptor; AC, adenylyl cyclase; ADD, Academic Drug Discovery center; cAMP, cyclic AMP; CRC, concentration response curve assay; DAR, dopamine receptor; DHX, dihydrexidine; EC, effective concentration; FDA, Food and Drug Admin