دانلود مقالات ISI درباره dCK، deoxycytidine kinase + ترجمه فارسی

رویکردهای تحلیلی مبتنی بر متابولومیکس به سرطان پانکراس

Analytical metabolomics-based approaches to pancreatic cancer

Keywords: dCK، deoxycytidine kinase; CDA, Cytidine deaminase; CP, Chronic pancreatitis; CT, Computed tomography; CTPS, Cytidine 5′-triphosphate synthetase; dCK, Deoxycytidine kinase; dFdC, 2′,2′-difluorodeoxycytidine or gemcitabine; dFdU, 2′,2′-difluorodeoxyuridine; hENT, Human equilibrative

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2014 سفارش ترجمه

IMP–GMP specific cytosolic 5′-nucleotidase regulates nucleotide pool and prodrug metabolism

Keywords: dCK، deoxycytidine kinase; cN-II, type II cytosolic 5′-nucleotidase; HGPRT, hypoxanthine-guanine phosphoribosyltransferase; ADA, adenosine deaminase; PNP, purine nucleoside phosphorylase; dCK, deoxycytidine kinase; CDA, deoxycytidine deaminase; GAPDH, glyceraldehyde-3-phosphate deh

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Gemcitabine-based therapy for pancreatic cancer using the squalenoyl nucleoside monophosphate nanoassemblies

Keywords: dCK، deoxycytidine kinase; dFdC, gemcitabine; dFdC-MP, gemcitabine monophosphate; dFdC-DP, gemcitabine diphosphate; dFdC-TP, gemcitabine triphosphate; dCK, deoxycytidine kinase; dFdU, 2′,2′-difluoro-2′-deoxyuridine; hENT1, human concentrative nucleoside transporter 1; PBS, phosphat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Differences in cytosolic and mitochondrial 5′-nucleotidase and deoxynucleoside kinase activities in Sprague–Dawley rat and CD-1 mouse tissues: Implication for the toxicity of nucleoside analogs in animal models

Keywords: dCK، deoxycytidine kinase; cN1, cytosolic 5′-nucleotidase 1; cN2, cytosolic 5′-nucleotidase 2; dNT, deoxynucleotidase; dCK, deoxycytidine kinase; TK1, thymidine kinase 1; TK2, thymidine kinase 2; AMP, adenosine monophosphate; (d)IMP, (deoxy)inosine monophosphate; dUMP, deoxyuridine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Modulation of human UMP/CMP kinase affects activation and cellular sensitivity of deoxycytidine analogs

Keywords: dCK، deoxycytidine kinase; 5-FU, 5-fluorouracil; 5-FUR, 5-fluorouridine; araC, 1-β-d-arabinofuranosylcytosine; dC, β-d-2′-deoxycytidine; Gem, 2′,2′-difluorodeoxycytidine, gemcitabine; MP, monophosphate; DP, diphosphate; TP, triphosphate; dCK, deoxycytidine kinase; CMPK, CMP kinase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Efficient overcoming of drug resistance to anticancer nucleoside analogs by nanodelivery of active phosphorylated drugs

Keywords: dCK، deoxycytidine kinase; dFdC, gemcitabine; araC, cytarabine; NATP, 5′-triphosphate of nucleoside analogs; CTP, cytidine 5′-triphosphate; dCK, deoxycytidine kinase; hENT1, human concentrative nucleoside transporter 1; NG, nanogel; PEI, polyethylenimine; MAL, maleimide; NHS, N-hyd

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of guanine-β-d-arabinofuranoside and deoxyguanosine to triphosphates by a common pathway blocks T lymphoblasts at different checkpoints

Keywords: dCK، deoxycytidine kinase; araG, guanine β-d-arabinofuranoside; araG-P, araG phosphates; araGTP, araG triphosphate; CdR, deoxycytidine; cyt, cytosolic; dATP, deoxyadenosine triphosphate; dCK, deoxycytidine kinase; dCTP, deoxycytidine triphosphate; dGK, deoxyguanosine kinase; dTMP,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Acute cytotoxicity of arabinofuranosyl nucleoside analogs is not dependent on mitochondrial DNA

Keywords: dCK، deoxycytidine kinase; araT, 1-β-D-arabinofuranosylthymine; araG, 9-β-D-arabinofuranosylguanine; EtBr, Ethidium bromide; BvDU, (E)-5-(2-bromovinyl)-2′-deoxyuridine; CdA, 2-chloro-2′-deoxyadenosine; Thd, Thymidine; dGK, deoxyguanosine kinase; dCK, deoxycytidine kinase; TK1, thym

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Mechanisms of anti-cancer action and pharmacology of clofarabine

Keywords: dCK، deoxycytidine kinase; ADA, adenosine deaminase; ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; AraC, cytarabine; CAFdA, clofarabine; CdA, cladribine; CLL, chronic lymphocytic leukemia; dCK, deoxycytidine kinase; dGK, deoxyguanosine kinase; DLT, dose-limiting t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Structural Basis for Substrate Promiscuity of dCK

Keywords: dCK، deoxycytidine kinase; dCK, deoxycytidine kinase; NA, nucleoside analog; C4S, a human dCK variant in which four cysteine residues (C9, C45, C59, and C146) were exchanged with serine; WT, wild typedeoxycytidine kinase; phosphoryl transfer; L-nucleosides; deoxyadenosine; crystal

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

Characterization of resistance to cytosine arabinoside (Ara-C) in NALM-6 human B leukemia cells

Keywords: dCK، deoxycytidine kinase; Ara-C, cytosine arabinoside (1-β-d-arabinofuranosylcytosine); ALL, acute lymphoblastic leukemia; RT-PCR, reverse transcription-polymerase chain reaction; hENT-1, human equilibrative nucleoside transporter-1; dCK, deoxycytidine kinase; CDA, cytidine deamin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Depletion of mtDNA: Syndromes and genes

Keywords: dCK، deoxycytidine kinase; mtDNA depletion; OXPHOS; Tissue specificityMDS, mtDNA depletion syndrome; DGUOK, deoxyguanosine kinase; TK2, thymidine kinase 2; POLG, DNA polymerase subunit γ1; SUCLA2, succinate-CoA ligase, ADP-forming, beta subunit; dCK, deoxycytidine kinase; SCAE, spi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Expression of deoxynucleoside kinases and 5′-nucleotidases in mouse tissues: Implications for mitochondrial toxicity

Keywords: dCK، deoxycytidine kinase; AMV-RT, avian myeloblastosis virus reverse transcriptase; cN-1b, cytosolic 5′-nucleotidase 1b; cN-2, cytosolic 5′-nucleotidase 2; dCK, deoxycytidine kinase; dGK, deoxyguanosine kinase; DNC, deoxynucleotide carrier; dNK, deoxynucleoside kinase; dNT-1, deox

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Depletion of mitochondrial DNA by down-regulation of deoxyguanosine kinase expression in non-proliferating HeLa cells

Keywords: dCK، deoxycytidine kinase; DGUOK, deoxyguanosine kinase; dCK, deoxycytidine kinase; araG, 9-β-d-arabinofuranosylguanine; TK1, thymidine kinase 1; TK2, thymidine kinase 2; mtDNA, mitochondrial DNA; siRNA, short interfering RNA; siDGUOK, short interfering RNA directed towards DGUOKMi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Structure-function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity

Keywords: dCK، deoxycytidine kinase; dNK, deoxyribonucleoside kinase; dN, deoxyribonucleoside; Mm-dAK, Mycoplasma mycoides subsp. mycoides small colony type deoxyadenosine kinase; dGK, deoxyguanosine kinase; dCK, deoxycytidine kinase; TK, thymidine kinase; TK1, thymidine kinase 1; TK2, thymi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The synergistic interaction of gemcitabine and cytosine arabinoside with the ribonucleotide reductase inhibitor triapine is schedule dependent

Keywords: dCK، deoxycytidine kinase; Gemcitabine; Cytosine arabinoside; Triapine; Synergistic interaction; Ribonucleotide reductase; Deoxycytidine kinasedFdC, gemcitabine (2′,2′-difluorodeoxycytidine; Gemzar); Ara-C, cytosine arabinoside; dCK, deoxycytidine kinase; dFdCDP, gemcitabine diphos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

An increase of cytochrome C oxidase mediated disruption of gemcitabine incorporation into DNA in a resistant KB clone

Keywords: dCK، deoxycytidine kinase; Gem, 2′,2′-dFdCyd,2,2-difluorodeoxycytidine, Gemcitabine; dCK, deoxycytidine kinase; dCMPK, dCMP kinase; NDPK, nucleoside diphosphate kinase; CK, cytidylate kinase; CCOX, cytochrome C oxidase; ENT, equilibrative nucleoside transporter; CNT, concentrative

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Comparative molecular field analysis and comparative molecular similarity indices analysis of human thymidine kinase 1 substrates

Keywords: dCK، deoxycytidine kinase; 3D-QSAR, three-dimensional quantitative structure-activity relationship; AZT, 3′-azido-2′,3′-dideoxythymidine; BNCT, boron neutron capture therapy; CoMFA, comparative molecular field analysis; CoMSIA, comparative molecular similarity indices analy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه