
Cellular senescence involves an intracrine prostaglandin E2 pathway in human fibroblasts
Keywords: ROS; reactive oxygen species; PGE2; prostaglandin E2; mPGES; prostaglandin E synthase; COX-2; cyclooxygenase 2; EP; prostaglandin E receptor; NHDFs; normal human dermal fibroblasts; SA-β-Gal; senescence associated-β-galactosidase; HUVECs; human umbilica