
Structural and Functional Analysis of C2-Type Ketoreductases from Modular Polyketide Synthases
Keywords: PKS, modular polyketide synthase; 6-dEB, 6-deoxyerythronolide B; DEBS, 6-deoxyerythronolide B synthase; PIKS, pikromycin synthase; KS, ketosynthase; KR, ketoreductase; ACP, acyl carrier protein; TE, thioesterase LDD, DEBS1 loading didomain; CDD, DEBS1 C-t