Effects of simvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, after oral and intravenous administration in rats: possible role of P-glycoprotein and CYP3A4 inhibition by simvastatin
Keywords: diltiazem; desacetyldiltiazem; simvastatin; CYP3A; P-gp; pharmacokinetics; bioavailability; rats