دانلود مقالات ISI درباره DFO، deferoxamine + ترجمه فارسی

مسدود کننده های کانال کلسیم موجب کاهش فیبروز کبدی مرتبط با اضافه بار آهن توسط تغییر انتقال آهن و آپوپتوز سلول ستون شده

Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis

Keywords: DFO، deferoxamine; CCB, calcium channel blocker; HSCs, hepatic stellate cells; DFO, deferoxamine; Tf, transferrin; TfR, transmembrane transferrin receptor; Ft, ferritin; LVDCCs, L-type voltage-dependent calcium channels; DMT-1, divalent metal transporter-1; ECM, extracellul

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

دخالت کمبود آهن در لیپوکسیلیت التهاب پالمیته سلولهای بتا

Involvement of iron depletion in palmitate-induced lipotoxicity of beta cells

Keywords: DFO، deferoxamine; Apoptosis; Endoplasmic reticulum (ER) stress; Lipotoxicity; INS-1 beta cell; Iron; PalmitateATF6, activating transcription factor-6; CHOP, C/EBP homologous protein; DFO, deferoxamine; DS, deferasirox; ER, endoplasmic reticulum; FFA, free fatty acid; FTH,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

خلاصه ای از هیدروژل های تزریقی پلیمری برای مهندسی بافت

An overview of injectable polymeric hydrogels for tissue engineering

Keywords: DFO، deferoxamine; APMA, aminopropyl methacrylamide; ASCs, Adipose Stem Cells; BMP, bone morphogenetic protein; CCL-5, chemokine ligand-5; DA, Diels–Alder; DFO, deferoxamine; DMOG, dimethyloxallyl glycine; ECFC, endothelial colony-forming cells; ECM, extra cellular matrix;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه

فعالیت ضد انعقادی و پیامدهای درمانی پتاسیم تریس (4-متیل-1-پریازولیل) بورو هیدرید در کارسینوم سلولهای استخوانی

Antiproliferative activity and therapeutic implications of potassium tris(4-methyl-1-pyrazolyl) borohydride in hepatocellular carcinoma

Keywords: DFO، deferoxamine; DFO, deferoxamine; KTp4-Me, potassium tris(4-methyl-1-pyrazolyl)-borohydride; ROS, reactive oxygen species; HCC, hepatocellular carcinoma; DMEM, Dulbecco’s modified Eagle’s medium; FBS, fetal bovine serum; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltet

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

لاکتوفرین از گاستروان گاوی، فعالیت پرولییل هیدروکسی ... 2 را تنظیم می کند و از طریق پروتون - پروتئین متصل به سلول های عصبی از طریق پروتئین پریون سلولی جلوگیری می کند

Lactoferrin from bovine colostrum regulates prolyl hydroxylase 2 activity and prevents prion protein-mediated neuronal cell damage via cellular prion protein

Keywords: DFO، deferoxamine; CHX, cycloheximide; DFO, deferoxamine; DMOG, dimethyloxalylglycine; EDTA, ethylenediaminetetraacetic acid; FBS, fetal bovine serum; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HIF-1α, hypoxia-inducible factor-1 alpha; ODD, oxygen degradatio

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The action of HIF-3α variants on HIF-2α–HIF-1β heterodimer formation is directly probed in live cells

Keywords: DFO، deferoxamine; bHLH, basic helix-loop-helix; DFO, deferoxamine; FRET, fluorescence resonance energy transfer; HIF, hypoxia-inducible factor; IPAS, inhibitory PAS domain; ODDD, oxygen-dependent degradation domain; PAS, Per-ARNT-Sim; PHD, prolyl hydroxylase; TAD, transact

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Artesunate induces apoptosis via a ROS-independent and Bax-mediated intrinsic pathway in HepG2 cells

Keywords: DFO، deferoxamine; ARS, artesunate; ART, artemisinin; ARTs, ART compounds; BSO, L-buthionine-sulfoximine; CCK-8, Cell Counting Kit-8; DCF-DA, 2′,7′-dichlorodihydrofluorescein diacetate; DHA, dihydroartemisinin; DFO, deferoxamine; FITC, fluorescein isothiocyanate; FCM, flow

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Intranasally-administered deferoxamine mitigates toxicity of 6-OHDA in a rat model of Parkinson׳s disease

Keywords: DFO، deferoxamine; DFO, deferoxamine; IN, intranasal; 6-OHDA, 6 hydroxydopamine; PD, Parkinson׳s disease; AD, Alzheimer׳s disease; TH IR, tyrosine hydroxylase immunoreactive; PBS, phosphate buffered saline; ICV, intracerebroventricular; LIP, labile iron pool; GSK3β, glycoge

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain

Keywords: DFO، deferoxamine; Aβ, amyloid-β; AD, Alzheimer’s disease; APP, amyloid precursor protein; CDK5, cyclin dependent kinase 5; DFO, deferoxamine; DMT1, divalent metal transporter 1; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GSK3β, glycogen synthase kinase 3β; HRP, horse

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: Implication in autosomal recessive juvenile Parkinsonism

Keywords: DFO، deferoxamine; AR-JP, autosomal recessive familial Parkinsonism; DFO, deferoxamine; DAergic, dopaminergic; EC, epicathecin; EGCG, epigallocathecin gallate; GA, gallic acid; GFP, green fluorescent protein; OS, oxidative stress; PQ, Paraquat; PD, Parkinson's disease; PG,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

TNF-α-stimulated macrophages protect A549 lung cells against iron and oxidation

Keywords: DFO، deferoxamine; AMs, alveolar macrophages; AMC, 7-amino-4-methyl-coumarin; AO, acridine orange; DFO, deferoxamine; ELF, epithelial lining fluid; GAPDH, glycerylaldehyde-3-phosphate dehydrogenase; γ-GCS, γ-glutamylcysteine synthetase; GO, glucose oxidase; GSH, reduced glu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The role of HIF in cobalt-induced ischemic tolerance

Keywords: DFO، deferoxamine; ANOVA, analysis of variance; DAPI, 4,6-diamidino-2-phenylindole; DFO, deferoxamine; DMEM, Dulbecco’s-modified Eagle medium; DMOG, dimethyloxylalyglycine; EPO, erythropoietin; FBS, fetal bovine serum; FIH, factor inhibiting HIF; HIF, hypoxia-inducible fact

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Transferrin receptor-1 suppresses neurite outgrowth in neuroblastoma Neuro2A cells

Keywords: DFO، deferoxamine; α-MEM, alpha modified minimum essential medium; apo-Tf, apo-transferrin; ATRA, all-trans retinoic acid; Dcytb, duodenal cytochrome-b; DFO, deferoxamine; DIV, days in vitro; DMEM, Dulbecco’s modified Eagle’s medium; DMT1, divalent metal transporter-1; FBS,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Nuclear coded mitochondrial protein prohibitin is an iron regulated iron binding protein

Keywords: DFO، deferoxamine; PHB, prohibitin; UTR, untranslated region; IRE, iron-response element; IRP, iron regulatory protein; FAC, ferric ammonium citrate; DFO, deferoxamine; GST, glutathione S-transferase; IL-6, interleukin 6; DAB, 3,3-diaminobenzidine tetrahydrochloride; TBHP,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Exposure to chrysotile asbestos causes carbonylation of glucose 6-phosphate dehydrogenase through a reaction with lipid peroxidation products in human lung epithelial cells

Keywords: DFO، deferoxamine; GSH, glutathione; G6PDH, glucose 6-phosphate dehydrogenase; DFO, deferoxamine; 4-HNE, 4-hydroxy-2-nonenal; MDA, malondialdehyde; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; t-BHP, t-butylhydroperoxide; TBARS, thiobarbituric acid-r

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1α and induction of autophagy in SH-SY5Y cells

Keywords: DFO، deferoxamine; ALP, autophagy-lysosome pathway; AVO, acidic vesicular organelles; DFO, deferoxamine; GFP, green fluorescent protein; HIF1-α, hypoxia-inducible factor 1alpha; LC3, microtubule-associated protein light chain 3; MPP+, 1-methyl-4-phenylpyridinium ion; O2, Ox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Lipofuscin-bound iron is a major intracellular source of oxidants: Role in senescent cells

Keywords: DFO، deferoxamine; Ac-R-L-R-AMC, N-acetyl-Arg-Leu-Arg-7-amino-4-methylcoumarin; Ac-DEVD-AMC, N-acetyl-Asp-Glu-Val-Asp-7-amino-4-methylcoumarin; DCF, 2′,7′-dichlorofluorescein; DFO, deferoxamine; DMPO, 5,5-dimethyl-1-pyrroline-N-oxide; DMSO, dimethyl sulfoxide; DTT, dithioth

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone

Keywords: DFO، deferoxamine; CHAPS, [(cholamidopropyl)dimethylammonio]-1-propane-sulfonate; DFO, deferoxamine; DFP, deferiprone; FO, feroxamine; FP, feriprone; HPLC, high-performance liquid chromatography; HYSS, Hyperquad Simulation and Speciation program; LPI, labile plasma iron; ML

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Iron species-mediated dopamine oxidation, proteasome inhibition, and dopaminergic cell demise: Implications for iron-related dopaminergic neuron degeneration

Keywords: DFO، deferoxamine; AM, aminochrome; CV, column volume; DA, dopamine; DFO, deferoxamine; GSH, glutathione; GSSG, glutathione disulfide; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; SN, substantia nigra; PD, Parkinson disease; ROS, reactive oxygen specie

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons

Keywords: DFO، deferoxamine; ALS, amyotrophic lateral sclerosis; DFO, deferoxamine; DMT1, divalent metal-ion transporter 1; IRE, iron-responsive element; IRP1, iron regulatory protein 1; LDH, lactate dehydrogenase; TBARS, thiobarbituric acid-reactive substances; TfR, transferrin rece

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

New insight into the influence of carob extract and gallic acid on hemin induced modulation of HT29 cell growth parameters

Keywords: DFO، deferoxamine; CAL, calcein; CDKN1A, cyclin-dependent kinase inhibitor 1A; CE, carob extract; DFO, deferoxamine; FCS, fetal calf serum; GA, gallic acid; GAPDH, glycerinaldehyd-3-phosphat-dehydrogenase; H2O2, hydrogen peroxideColorectal cancer; Iron; Heme; Ceratonia sili

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Iron deficiency down-regulates the Akt/TSC1-TSC2/mammalian Target of Rapamycin signaling pathway in rats and in COS-1 cells

Keywords: DFO، deferoxamine; 4E-BP, eukaryote initiation factor 4E binding protein; DFO, deferoxamine; ID, iron deficiency; mTOR, mammalian Target of Rapamycin; Rheb, Ras homolog enriched in brain; S6K, S6 kinase; TSC, tuberous sclerosis complexIron deficiency (ID); mammalian Target

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

The role and regulation of hypoxia-inducible factor-1α expression in brain development and neonatal hypoxic–ischemic brain injury

Keywords: DFO، deferoxamine; ARD1, arrest-defective-1; ARNT, aryl hydrocarbon nuclear translocator; BBB, blood-brain barrier; BNIP3, BCL2/adenovirus E1B interacting protein 3; C-TAD, C-terminal domain; DFO, deferoxamine; 3,4-DHB, 3,4-dihydroxybenzoate; EPO, erythropoietin; EPOR, EPO

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Polyol pathway mediates iron-induced oxidative injury in ischemic–reperfused rat heart

Keywords: DFO، deferoxamine; AAR, area at risk; AR, aldose reductase; ARI, aldose reductase inhibitor; ATP, adenosine triphosphate; CAL, coronary artery ligation; DFO, deferoxamine; GAPDH, glyceraldehydes-3-phosphate dehydrogenase; GSH, glutathione; HR, heart rate; HIF-1α, hypoxia in

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Therapeutics for neonatal brain injury

Keywords: DFO، deferoxamine; AMPA, alpha-3amino-hydroxy-5-methyl-4-isoxazole propionic acid; CNS, central nervous system; DFO, deferoxamine; EPO, erythropoietin; GPx, glutathione peroxidase; HI, hypoxia-ischemia; HIF-1alpha, hypoxia inducible factor-1alpha; NMDA, N-methyl-d-aspartate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Regulation of hepcidin in HepG2 and RINm5F cells

Keywords: DFO، deferoxamine; IL-6, interleukin-6; LPS, lipopolysaccharide; Epo, erythropoietin; DFO, deferoxamine; TBST, tris-buffered saline containing Tween® 20Hepcidin; Pro-hepcidin; Iron metabolism; Pancreas; Liver

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Iron supplementation protects against lead-induced apoptosis through MAPK pathway in weanling rat cortex

Keywords: DFO، deferoxamine; CNS, central nervous system; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated protein kinase; JNK, c-Jun N-terminal kinase; TUNEL, terminal transferase-mediated dUTP nick end-labeling; DFO, deferoxamine; DAB, diaminobenzidineLea

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Vanadium Induces VL30 Retrotransposition at an Unusually High Level: A Possible Carcinogenesis Mechanism

Keywords: DFO، deferoxamine; VL30s, viral-like 30 elements; EGFP, enhanced green fluorescent protein; FACS, fluorescence-activated cell scanning; NAC, N-acetyl-cysteine; DFO, deferoxamine; enRTs, endogenous reverse transcriptases; DSB, double-strand break; ROS, reactive oxygen specie

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition

Keywords: DFO، deferoxamine; BQ, 1,4-benzoquinone; DFO, deferoxamine; DMNQ, 2,3-dimethoxy-1,4-naphthoquinone; DPI, diphenyleneiodonium chloride; GSH, reduced glutathione; GSSG, glutathione disulfide; LDH, lactate dehydrogenase; NAC, N-acetyl cysteine; ROS, reactive oxygen species; SK

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Iron chelator induces THP-1 cell differentiation potentially by modulating intracellular glutathione levels

Keywords: DFO، deferoxamine; DFO, deferoxamine; IL, interleukin; PMA, phorbol-12-myristate-13-acetate; MIM, mimosine; SR-A, scavenger receptor A; ERK, extracellular signal-regulated kinase; NAC, N-acetyl-cysteine; FC, ferric citrate; FN, fibronectine; DN, dominant-negative; PBS, phos

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

The superoxide dismutase inhibitor diethyldithiocarbamate has antagonistic effects on apoptosis by triggering both cytochrome c release and caspase inhibition

Keywords: DFO، deferoxamine; BHA, butylated hydroxyanisole; BSA, bovine serum albumin; Cyt c, cytochrome c; DCFH-DA, 2′,7′-dichlorodihydrofluorescein diacetate; DDC, diethyldithiocarbamate; DDT, dithiotreitol; DFO, deferoxamine; DiOC6(3), 3,3′-diethyloxacarbocyanine; DISC, death-indu

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه