Keywords: Schistosoma mansoni; Nucleotide metabolism; Dihydrofolate reductase (DHFR); Isothermal titration calorimetry (ITC); X-ray crystallography; DHFR; dihydrofolate reductase; rSmDHFR; recombinant Schistosoma mansoni DHFR; NADPH and NADP+; nicotinamide adenine
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1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity
Keywords: Dihydrofolate reductase (DHFR); Antimycobacterial agent; Tuberculosis (TB); 1,3,5-triazaspiro[5.5]undeca-2,4-diene; DHFR; dihydrofolate reductase; DMPK; drug metabolism and pharmacokinetics; FRLM; female rat liver microsomes; HBA; hydrogen bond acceptors;
NOX isoforms in the development of abdominal aortic aneurysm
Keywords: Abdominal aortic aneurysms (AAA); Angiotensin II (Ang II); Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase/NOX); NOX1; NOX2; NOX4; p47phox; Endothelial nitric oxide synthase (eNOS) uncoupling; Dihydrofolate reductase (DHFR); Superoxide;
Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition
Keywords: Sanguinarine; Basal-like breast cancer; Dihydrofolate reductase (DHFR); STAT3; Apoptosis; Mice;
Identification and analysis of specific chromosomal region adjacent to exogenous Dhfr-amplified region in Chinese hamster ovary cell genome
Keywords: Bacterial artificial chromosome library; Chinese hamster ovary cell; Gene amplification; Dihydrofolate reductase (DHFR); Genome; Palindrome structure
Novel point mutations in sulfadoxine resistance genes of Plasmodium falciparum from India
Keywords: Plasmodium falciparum; Sulfadoxine; Pyrimethamine; Dihydrofolate reductase (DHFR); Dihydropteroate synthase (DHPS)
Mechanistic insights into folic acid-dependent vascular protection: Dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: A novel HPLC-based fluorescent assay for DHFR activity
Keywords: Folic acid (FA); Dihydrofolate reductase (DHFR); Endothelial nitric oxide synthase (eNOS); Nitric oxide (NO); Angiotensin II (Ang II); Tetrahydrofolic acid (THF)