Keywords: DED, death effector domain; DISC, death inducing signaling complex; TNF, tumor necrosis factor; TNFRI, tumor necrosis factor receptor I; Z-VAD-FMK, benzoxycarbonyl-Val-Ala-Asp-fluoromethyl ketoneApoptosis; Necrosis; Necroptosis; Autophagy
مقالات ISI (ترجمه نشده)
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Targeting apoptotic and autophagic pathways for cancer therapeutics
Keywords: Cancer; Apoptosis; Autophagy; PathwaysApaf-1, apoptotic protease activating factor-1; BH, Bcl-2homology; DISC, death inducing signaling complex; FADD, Fas-associated death domain protein; PARP, poly(ADP-ribose)polymerase; ICAD, inhibitor of caspase-activa
Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR2
Keywords: BS3, bis-(sulfosuccinimidyl)-suberate; CRD, cysteine rich domain; DISC, death inducing signaling complex; FADD, Fas-associating protein with death domain; FasL, Fas ligand; HEK, human embryonic kidney; KD, dissociation constant; mAb, monoclonal antibody;
Multistep and multitask Bax activation
Keywords: AIF, apoptosis inducing factor; ANT, adenine nucleotide translocator; AP-1, activator protein-1; Bax, Bcl-2 homolog X; Bcl-2, B-cell lymphoma-2; BH, Bcl-2-homology; DISC, death inducing signaling complex; ER, endoplasmic reticulum; IAP, inhibitor of apopt
FADD–calmodulin interaction: A novel player in cell cycle regulation
Keywords: GST, glutathione S-transferase; mFADD, murine FADD; dFADD, Drosophila FADD; CaM, calmodulin; DED, death effector domain; DD, death domain; DISC, death inducing signaling complex; CKIα, casein kinase I alpha; TNFRI, tumor necrosis factor receptor IFADD; Ca
Phenylarsine oxide interferes with the death inducing signaling complex and inhibits tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced apoptosis
Keywords: TNF, tumor necrosis factor; TRAIL, TNF-related apoptosis-inducing ligand; DISC, death inducing signaling complex; FADD, Fas-associated death domain; PTPase, protein tyrosine phosphatase; CRD, cysteine rich domain; ANT, adenine nucleotide transporter; PS,
A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells
Keywords: AICD, activation induced cell death; DISC, death inducing signaling complex; SH3, Src homology 3; ICD, intracellular domain; LC-MSMS, liquid chromatography coupled tandem mass spectrometry; IRES, internal ribosomal entry site; GST, glutathione-S-transfera
P60-c-src suppresses apoptosis through inhibition of caspase 8 activation in hepatoma cells, but not in primary hepatocytes
Keywords: AZD0530 and AZM475271, anilinoquinazoline inhibitors of c-Src; DISC, death inducing signaling complex; SFK, Src family kinase; PP2, 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine; TRAIL, tumor necrosis factor-related apoptosis inducing li
Exposure to inorganic mercury in vivo attenuates extrinsic apoptotic signaling in Staphylococcal aureus enterotoxin B stimulated T-cells
Keywords: Hg, mercury; HgIA, mercury induced autoimmunity; DISC, death inducing signaling complex; SEB, Staphylococcal aureus enterotoxin B; AICD, activation induced cell death; MFI, mean fluorescence intensity; ALPS, autoimmune lymphoproliferative syndromeT-cells;
Genetic Inactivation of RelA/p65 Sensitizes Adult Mouse Hepatocytes to TNF-induced Apoptosis In Vivo and In Vitro
Keywords: BHA, butylated hydroxyanisole; c-FLIP, cellular FLICE inhibitor protein; c-FLIPl, long splice form of c-FLIP; c-FLIPs, short splice form of c-FLIP; DD, death domain; DISC, death inducing signaling complex; FLICE, FADD-like Interleukin-1β-converting enzyme
Targeting Death Receptors in Bladder, Prostate and Renal Cancer
Keywords: bladder neoplasms; prostate neoplasms; kidney neoplasms; apoptosis; immune systemAR, androgen receptor; cFLIP, cellular FLICE-inhibitory protein; DcR, decoy receptor; DISC, death inducing signaling complex; DR, death receptor; FADD, FAS-associated death d