
Keywords: Aldose reductase inhibitors; 1-Hydroxypyrazole; Trifluoroacetylation; Sorbitol accumulation; Differential inhibitors; ALR2; aldose reductase; ALR1; aldehyde reductase; AP-1; activator protein 1; ARIs; aldose reductase inhibitors; DHN; 1,4-dihydroxynonene;