Targeting PI3 kinase in cancer
Keywords: PI3K pathway; Isoforms; Review; PI3K inhibitors; PI3K/Akt/mTORAE, Adverse event; ALT, Alanine transaminase; AST, Aspartate transaminase; CLL, Chronic lymphocytic leukemia; DLT, Dose-limiting toxicity; FDA, Food and Drug Administration; GIST, Gastrointesti