
Chitosan oligosaccharides reduce acetaminophen-induced hepatotoxicity by suppressing CYP-mediated bioactivation
Keywords: ALT, alanine aminotransferase; APAP, acetaminophen; COS, chitosan oligosaccharide; CYP, cytochrome P-450; DME, drug-metabolizing enzyme; EDTA, ethylenediaminetetraacetic acid; GSH, reduced glutathione; GST, glutathione S-transferase; HO-1, heme oxygenase