
Inhibition of in vitro metabolism of testosterone in human, dog and horse liver microsomes to investigate species differences
Keywords: CYPs, cytochrome P450 enzymes; DMSO, dimethyl-sulphoxide; OH-TES, hydroxytestosterone; 17β HSD type 2, hydroxysteroid (17β) dehydrogenase 2; hLM, human liver microsomes; cLM, canine liver microsomes; eLM, equine liver microsomes; NADPH, nicotinamide adeni