Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure
Keywords: دی متیل سولفوکسید; SARS-CoV, severe acute respiratory syndrome coronavirus; 3CLpro, 3C-like protease; RMSD, root-mean-square deviation; MES, 2-(N-morpholino)ethanesulfonic acid; PEG, polyethylene glycol; DTT, dithiothreitol; DMSO, dimethyl sulphoxide; EDTA, ethylene diamine